Search Results - "Ellisman, MH"

Structural basis for delta cell paracrine regulation in pancreatic islets by Arrojo e Drigo, Rafael, Jacob, Stefan, García-Prieto, Concha F., Zheng, Xiaofeng, Fukuda, Masahiro, Nhu, Hoa Tran Thi, Stelmashenko, Olga, Peçanha, Flavia Letícia Martins, Rodriguez-Diaz, Rayner, Bushong, Eric, Deerinck, Thomas, Phan, Sebastien, Ali, Yusuf, Leibiger, Ingo, Chua, Minni, Boudier, Thomas, Song, Sang-Ho, Graf, Martin, Augustine, George J., Ellisman, Mark H., Berggren, Per-Olof

“…Little is known about the role of islet delta cells in regulating blood glucose homeostasis in vivo. Delta cells are important paracrine regulators of beta…”
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High resolution three‐dimensional reconstruction of fibrotic skeletal muscle extracellular matrix by Gillies, Allison R., Chapman, Mark A., Bushong, Eric A., Deerinck, Thomas J., Ellisman, Mark H., Lieber, Richard L.

“…Key points Fibrosis occurs secondary to many skeletal muscle diseases and injuries, and can alter muscle function. It is unknown how collagen, the most…”
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STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane by ZHANG, Shenyuan L, YING YU, ROOS, Jack, ASHOT KOZAK, J, DEERINCK, Thomas J, ELLISMAN, Mark H, STAUDERMAN, Kenneth A, CAHALAN, Michael D

“…As the sole Ca2+ entry mechanism in a variety of non-excitable cells, store-operated calcium (SOC) influx is important in Ca2+ signalling and many other…”
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Bid, Bax, and Lipids Cooperate to Form Supramolecular Openings in the Outer Mitochondrial Membrane by Kuwana, Tomomi, Mackey, Mason R., Perkins, Guy, Ellisman, Mark H., Latterich, Martin, Schneiter, Roger, Green, Douglas R., Newmeyer, Donald D.

“…Bcl-2 family proteins regulate the release of proteins like cytochrome c from mitochondria during apoptosis. We used cell-free systems and ultimately a…”
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Protoplasmic Astrocytes in CA1 Stratum Radiatum Occupy Separate Anatomical Domains by Bushong, Eric A, Martone, Maryann E, Jones, Ying Z, Ellisman, Mark H

“…Protoplasmic astrocytes are increasingly thought to interact extensively with neuronal elements in the brain and to influence their activity. Recent reports…”
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Correlated light and electron microscopic imaging of multiple endogenous proteins using Quantum dots by Ellisman, Mark H, Giepmans, Ben N G, Deerinck, Thomas J, Smarr, Benjamin L, Jones, Ying Z

“…The importance of locating proteins in their context within cells has been heightened recently by the accomplishments in molecular structure and systems…”
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Disruption of Mitochondrial Function during Apoptosis Is Mediated by Caspase Cleavage of the p75 Subunit of Complex I of the Electron Transport Chain by Ricci, Jean-Ehrland, Muñoz-Pinedo, Cristina, Fitzgerald, Patrick, Bailly-Maitre, Béatrice, Perkins, Guy A, Yadava, Nagendra, Scheffler, Immo E, Ellisman, Mark H, Green, Douglas R

“…Mitochondrial outer membrane permeabilization and cytochrome c release promote caspase activation and execution of apoptosis through cleavage of specific…”
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Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptors by Malenka, Robert C, Ju, William, Morishita, Wade, Tsui, Jennifer, Gaietta, Guido, Deerinck, Thomas J, Adams, Stephen R, Garner, Craig C, Tsien, Roger Y, Ellisman, Mark H

“…Regulation of AMPA receptor (AMPAR) trafficking is important for neural plasticity. Here we examined the trafficking and synthesis of the GluR1 and GluR2…”
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Multicolor and Electron Microscopic Imaging of Connexin Trafficking by Gaietta, Guido, Deerinck, Thomas J., Adams, Stephen R., Bouwer, James, Tour, Oded, Laird, Dale W., Sosinsky, Gina E., Tsien, Roger Y., Ellisman, Mark H.

“…Recombinant proteins containing tetracysteine tags can be successively labeled in living cells with different colors of biarsenical fluorophores so that older…”
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JNK1 Is Required for Maintenance of Neuronal Microtubules and Controls Phosphorylation of Microtubule-Associated Proteins by Chang, Lufen, Jones, Ying, Ellisman, Mark H., Goldstein, Lawrence S.B., Karin, Michael

“…Microtubules (MTs) play an important role in elaboration and maintenance of axonal and dendritic processes. MT dynamics are modulated by MT-associated proteins…”
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Crosstalk between Nitric Oxide and Zinc Pathways to Neuronal Cell Death Involving Mitochondrial Dysfunction and p38-Activated K+ Channels by Bossy-Wetzel, Ella, Talantova, Maria V, Lee, Wilson D, Schölzke, Marion N, Harrop, Anne, Mathews, Emily, Götz, Thomas, Han, Jiahuai, Ellisman, Mark H, Perkins, Guy A, Lipton, Stuart A

“…Nitric oxide (NO) and zinc (Zn2+) are implicated in the pathogenesis of cerebral ischemia and neurodegenerative diseases. However, their relationship and the…”
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Differential distribution of closely related potassium channels in rat Schwann cells by Mi, H, Deerinck, TJ, Ellisman, MH, Schwarz, TL

“…Closely related K+ channels can coassemble to form heteromultimers in expression systems, as well as in vivo. Whether in vivo this coassembly is random and…”
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The Arg451Cys-Neuroligin-3 Mutation Associated with Autism Reveals a Defect in Protein Processing by Comoletti, Davide, De Jaco, Antonella, Jennings, Lori L, Flynn, Robyn E, Gaietta, Guido, Tsigelny, Igor, Ellisman, Mark H, Taylor, Palmer

“…The neuroligins are a family of postsynaptic transmembrane proteins that associate with presynaptic partners, the beta-neurexins. Neurexins and neuroligins…”
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Maturation of astrocyte morphology and the establishment of astrocyte domains during postnatal hippocampal development by Bushong, Eric A., Martone, Maryann E., Ellisman, Mark H.

“…Mature protoplasmic astrocytes exhibit an extremely dense ramification of fine processes, yielding a ‘spongiform’ morphology. This complex morphology enables…”
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Axonal activation-induced calcium transients in myelinating Schwann cells, sources, and mechanisms by Lev-Ram, V, Ellisman, MH

“…We have investigated the role of myelinating glia in events associated with propagation of the action potential at nodes of Ranvier using combinations of…”
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Spatial mapping of integrin interactions and dynamics during cell migration by image correlation microscopy by Wiseman, Paul W, Brown, Claire M, Webb, Donna J, Hebert, Benedict, Johnson, Natalie L, Squier, Jeff A, Ellisman, Mark H, Horwitz, A F

“…Image correlation microscopy methodology was extended and used to determine retrospectively the density, dynamics and interactions of alpha5-integrin in…”
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Author Correction: Structural basis for delta cell paracrine regulation in pancreatic islets by e Drigo, Rafael Arrojo, Jacob, Stefan, García-Prieto, Concha F., Zheng, Xiaofeng, Fukuda, Masahiro, Nhu, Hoa Tran Thi, Stelmashenko, Olga, Peçanha, Flavia Letícia Martins, Rodriguez-Diaz, Rayner, Bushong, Eric, Deerinck, Thomas, Phan, Sebastien, Ali, Yusuf, Leibiger, Ingo, Chua, Minni, Boudier, Thomas, Song, Sang-Ho, Graf, Martin, Augustine, George J., Ellisman, Mark H., Berggren, Per-Olof

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Transform-based backprojection for volume reconstruction of large format electron microscope tilt series by Lawrence, Albert, Bouwer, James C., Perkins, Guy, Ellisman, Mark H.

“…Alignment of the individual images of a tilt series is a critical step in obtaining high-quality electron microscope reconstructions. We report on general…”
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e-Neuroscience: challenges and triumphs in integrating distributed data from molecules to brains by Ellisman, Mark H, Martone, Maryann E, Gupta, Amarnath

“…Imaging, from magnetic resonance imaging (MRI) to localization of specific macromolecules by microscopies, has been one of the driving forces behind…”
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Evidence for Ectopic Neurotransmission at a Neuronal Synapse by Coggan, Jay S, Bartol, Thomas M, Esquenazi, Eduardo, Stiles, Joel R, Lamont, Stephan, Martone, Maryann E, Berg, Darwin K, Ellisman, Mark H, Sejnowski, Terrence J

“…Neurotransmitter release is well known to occur at specialized synaptic regions that include presynaptic active zones and postsynaptic densities. At…”
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