Search Results - "Elliott, Melissa"

Allogeneic natural killer cell therapy by Berrien-Elliott, Melissa M., Jacobs, Miriam T., Fehniger, Todd A.

“…[Display omitted] Interest in adoptive cell therapy for treating cancer is exploding owing to early clinical successes of autologous chimeric antigen receptor…”
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Memory-like natural killer cells for cancer immunotherapy by Gang, Margery, Wong, Pamela, Berrien-Elliott, Melissa M., Fehniger, Todd A.

“…•NK cell are innate lymphoid cells that exhibit memory and memory-like responses.•Cytokine-induced memory-like (ML) NK cells are induced via IL-12, IL-15, and…”
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Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia by Romee, Rizwan, Rosario, Maximillian, Berrien-Elliott, Melissa M, Wagner, Julia A, Jewell, Brea A, Schappe, Timothy, Leong, Jeffrey W, Abdel-Latif, Sara, Schneider, Stephanie E, Willey, Sarah, Neal, Carly C, Yu, Liyang, Oh, Stephen T, Lee, Yi-Shan, Mulder, Arend, Claas, Frans, Cooper, Megan A, Fehniger, Todd A

“…Natural killer (NK) cells are an emerging cellular immunotherapy for patients with acute myeloid leukemia (AML); however, the best approach to maximize NK cell…”
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CAR-modified memory-like NK cells exhibit potent responses to NK-resistant lymphomas by Gang, Margery, Marin, Nancy D., Wong, Pamela, Neal, Carly C., Marsala, Lynne, Foster, Mark, Schappe, Timothy, Meng, Wei, Tran, Jennifer, Schaettler, Maximilian, Davila, Marco, Gao, Feng, Cashen, Amanda F., Bartlett, Nancy L., Mehta-Shah, Neha, Kahl, Brad S., Kim, Miriam Y., Cooper, Matthew L., DiPersio, John F., Berrien-Elliott, Melissa M., Fehniger, Todd A.

“…Natural killer (NK) cells are a promising cellular immunotherapy for cancer. Cytokine-induced memory-like (ML) NK cells differentiate after activation with…”
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Recurrent somatic mutations affecting B-cell receptor signaling pathway genes in follicular lymphoma by Krysiak, Kilannin, Gomez, Felicia, White, Brian S., Matlock, Matthew, Miller, Christopher A., Trani, Lee, Fronick, Catrina C., Fulton, Robert S., Kreisel, Friederike, Cashen, Amanda F., Carson, Kenneth R., Berrien-Elliott, Melissa M., Bartlett, Nancy L., Griffith, Malachi, Griffith, Obi L., Fehniger, Todd A.

“…Follicular lymphoma (FL) is the most common form of indolent non-Hodgkin lymphoma, yet it remains only partially characterized at the genomic level. To improve…”
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Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development by Dege, Carissa, Fegan, Katherine H., Creamer, J. Philip, Berrien-Elliott, Melissa M., Luff, Stephanie A., Kim, Darren, Wagner, Julia A., Kingsley, Paul D., McGrath, Kathleen E., Fehniger, Todd A., Palis, James, Sturgeon, Christopher M.

“…Natural killer (NK) cells are a critical component of the innate immune system. However, their ontogenic origin has remained unclear. Here, we report that NK…”
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Donor memory-like NK cells persist and induce remissions in pediatric patients with relapsed AML after transplant by Bednarski, Jeffrey J., Zimmerman, Clare, Berrien-Elliott, Melissa M., Foltz, Jennifer A., Becker-Hapak, Michelle, Neal, Carly C., Foster, Mark, Schappe, Timothy, McClain, Ethan, Pence, Patrick P., Desai, Sweta, Kersting-Schadek, Samantha, Wong, Pamela, Russler-Germain, David A., Fisk, Bryan, Lie, Wen-Rong, Eisele, Jeremy, Hyde, Stephanie, Bhatt, Sima T., Griffith, Obi L., Griffith, Malachi, Petti, Allegra A., Cashen, Amanda F., Fehniger, Todd A.

“…Pediatric and young adult (YA) patients with acute myeloid leukemia (AML) who relapse after allogeneic hematopoietic cell transplantation (HCT) have an…”
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First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation by Romee, Rizwan, Cooley, Sarah, Berrien-Elliott, Melissa M., Westervelt, Peter, Verneris, Michael R., Wagner, John E., Weisdorf, Daniel J., Blazar, Bruce R., Ustun, Celalettin, DeFor, Todd E., Vivek, Sithara, Peck, Lindsey, DiPersio, John F., Cashen, Amanda F., Kyllo, Rachel, Musiek, Amy, Schaffer, András, Anadkat, Milan J., Rosman, Ilana, Miller, Daniel, Egan, Jack O., Jeng, Emily K., Rock, Amy, Wong, Hing C., Fehniger, Todd A., Miller, Jeffrey S.

“…New therapies for patients with hematologic malignancies who relapse after allogeneic hematopoietic cell transplantation (allo-HCT) are needed. Interleukin 15…”
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Immunotherapeutic approach to reduce senescent cells and alleviate senescence‐associated secretory phenotype in mice by Shrestha, Niraj, Chaturvedi, Pallavi, Zhu, Xiaoyun, Dee, Michael J., George, Varghese, Janney, Christopher, Egan, Jack O., Liu, Bai, Foster, Mark, Marsala, Lynne, Wong, Pamela, Cubitt, Celia C., Foltz, Jennifer A., Tran, Jennifer, Schappe, Timothy, Hsiao, Karin, Leclerc, Gilles M., You, Lijing, Echeverri, Christian, Spanoudis, Catherine, Carvalho, Ana, Kanakaraj, Leah, Gilkes, Crystal, Encalada, Nicole, Kong, Lin, Wang, Meng, Fang, Byron, Wang, Zheng, Jiao, Jin‐an, Muniz, Gabriela J., Jeng, Emily K., Valdivieso, Nicole, Li, Liying, Deth, Richard, Berrien‐Elliott, Melissa M., Fehniger, Todd A., Rhode, Peter R., Wong, Hing C.

“…Accumulation of senescent cells (SNCs) with a senescence‐associated secretory phenotype (SASP) has been implicated as a major source of chronic sterile…”
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Systemic IL-15 promotes allogeneic cell rejection in patients treated with natural killer cell adoptive therapy by Berrien-Elliott, Melissa M., Becker-Hapak, Michelle, Cashen, Amanda F., Jacobs, Miriam, Wong, Pamela, Foster, Mark, McClain, Ethan, Desai, Sweta, Pence, Patrick, Cooley, Sarah, Brunstein, Claudio, Gao, Feng, Abboud, Camille N., Uy, Geoffrey L., Westervelt, Peter, Jacoby, Meagan A., Pusic, Iskra, Stockerl-Goldstein, Keith E., Schroeder, Mark A., DiPersio, John F., Soon-Shiong, Patrick, Miller, Jeffrey S., Fehniger, Todd A.

“…Natural killer (NK) cells are a promising alternative to T cells for cancer immunotherapy. Adoptive therapies with allogeneic, cytokine-activated NK cells are…”
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Combining AFM13, a Bispecific CD30/CD16 Antibody, with Cytokine-Activated Blood and Cord Blood-Derived NK Cells Facilitates CAR-like Responses Against CD30 + Malignancies by Kerbauy, Lucila N, Marin, Nancy D, Kaplan, Mecit, Banerjee, Pinaki P, Berrien-Elliott, Melissa M, Becker-Hapak, Michelle, Basar, Rafet, Foster, Mark, Garcia Melo, Luciana, Neal, Carly C, McClain, Ethan, Daher, May, Nunez Cortes, Ana Karen, Desai, Sweta, Inng Lim, Francesca Wei, Mendt, Mayela Carolina, Schappe, Timothy, Li, Li, Shaim, Hila, Shanley, Mayra, Ensley, Emily L, Uprety, Nadima, Wong, Pamela, Liu, Enli, Ang, Sonny O, Cai, Rong, Nandivada, Vandana, Mohanty, Vakul, Miao, Qi, Shen, Yifei, Baran, Natalia, Fowlkes, Natalie W, Chen, Ken, Muniz-Feliciano, Luis, Champlin, Richard E, Nieto, Yago L, Koch, Joachim, Treder, Martin, Fischer, Wolfgang, Okamoto, Oswaldo Keith, Shpall, Elizabeth J, Fehniger, Todd A, Rezvani, Katayoun

“…Natural killer (NK)-cell recognition and function against NK-resistant cancers remain substantial barriers to the broad application of NK-cell immunotherapy…”
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Mir-223 regulates the number and function of myeloid-derived suppressor cells in multiple sclerosis and experimental autoimmune encephalomyelitis by Cantoni, Claudia, Cignarella, Francesca, Ghezzi, Laura, Mikesell, Bob, Bollman, Bryan, Berrien-Elliott, Melissa M., Ireland, Aaron R., Fehniger, Todd A., Wu, Gregory F., Piccio, Laura

“…Myeloid-derived cells play important modulatory and effector roles in multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis…”
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MicroRNA-146a deficiency enhances host protection against murine cytomegalovirus by Wong, Pamela, Leong, Jeffrey W, Sohn, Hyogon, Chang, Lily, Keppel, Catherine R, Neal, Carly C, Cubitt, Celia C, Yao, Tony, Keppel, Molly P, Tran, Jennifer, Burdi, Allison, Hwang, Kimberly, Fogel, Leslie A, Schappe, Timothy, Marsala, Lynne, Berrien-Elliott, Melissa M, Wagner, Julia A, Schneider, Stephanie E, Sullivan, Ryan P, Pingel, Jeanette T, Cooper, Megan A, French, Anthony R, Fehniger, Todd A

“…Natural killer (NK) cells are innate lymphoid cells that protect a host from viral infections and malignancies. MicroRNA-146a (miR-146a) is an important…”
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CD56bright NK cells exhibit potent antitumor responses following IL-15 priming by Wagner, Julia A, Rosario, Maximillian, Romee, Rizwan, Berrien-Elliott, Melissa M, Schneider, Stephanie E, Leong, Jeffrey W, Sullivan, Ryan P, Jewell, Brea A, Becker-Hapak, Michelle, Schappe, Timothy, Abdel-Latif, Sara, Ireland, Aaron R, Jaishankar, Devika, King, Justin A, Vij, Ravi, Clement, Dennis, Goodridge, Jodie, Malmberg, Karl-Johan, Wong, Hing C, Fehniger, Todd A

“…NK cells, lymphocytes of the innate immune system, are important for defense against infectious pathogens and cancer. Classically, the CD56dim NK cell subset…”
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Costimulatory domains direct distinct fates of CAR-driven T-cell dysfunction by Selli, Mehmet Emrah, Landmann, Jack H., Terekhova, Marina, Lattin, John, Heard, Amanda, Hsu, Yu-Sung, Chang, Tien-Ching, Chang, Jufang, Warrington, John, Ha, Helen, Kingston, Natalie, Hogg, Graham, Slade, Michael, Berrien-Elliott, Melissa M., Foster, Mark, Kersting-Schadek, Samantha, Gruszczynska, Agata, DeNardo, David, Fehniger, Todd A., Artyomov, Maxim, Singh, Nathan

“…•Chronic stimulation of CD28-based CARs drives T cells to become exhausted, but 41BB-based CARs direct a novel state of T-cell dysfunction.•41BB-driven T-cell…”
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Memory-like Differentiation Enhances NK Cell Responses to Melanoma by Marin, Nancy D, Krasnick, Bradley A, Becker-Hapak, Michelle, Conant, Leah, Goedegebuure, Simon P, Berrien-Elliott, Melissa M, Robbins, Keenan J, Foltz, Jennifer A, Foster, Mark, Wong, Pamela, Cubitt, Celia C, Tran, Jennifer, Wetzel, Christopher B, Jacobs, Miriam, Zhou, Alice Y, Russler-Germain, David, Marsala, Lynne, Schappe, Timothy, Fields, Ryan C, Fehniger, Todd A

“…Treatment of advanced melanoma is a clinical challenge. Natural killer (NK) cells are a promising cellular therapy for T cell-refractory cancers, but are…”
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Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia by Berrien-Elliott, Melissa M, Foltz, Jennifer A, Russler-Germain, David A, Neal, Carly C, Tran, Jennifer, Gang, Margery, Wong, Pamela, Fisk, Bryan, Cubitt, Celia C, Marin, Nancy D, Zhou, Alice Y, Jacobs, Miriam T, Foster, Mark, Schappe, Timothy, McClain, Ethan, Kersting-Schadek, Samantha, Desai, Sweta, Pence, Patrick, Becker-Hapak, Michelle, Eisele, Jeremy, Mosior, Matthew, Marsala, Lynne, Griffith, Obi L, Griffith, Malachi, Khan, Saad M, Spencer, David H, DiPersio, John F, Romee, Rizwan, Uy, Geoffrey L, Abboud, Camille N, Ghobadi, Armin, Westervelt, Peter, Stockerl-Goldstein, Keith, Schroeder, Mark A, Wan, Fei, Lie, Wen-Rong, Soon-Shiong, Patrick, Petti, Allegra A, Cashen, Amanda F, Fehniger, Todd A

“…Natural killer (NK) cells are innate lymphoid cells that eliminate cancer cells, produce cytokines, and are being investigated as a nascent cellular…”
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Synthetic Cationic Peptide IDR-1002 Provides Protection against Bacterial Infections through Chemokine Induction and Enhanced Leukocyte Recruitment by Nijnik, Anastasia, Madera, Laurence, Ma, Shuhua, Waldbrook, Matthew, Elliott, Melissa R, Easton, Donna M, Mayer, Matthew L, Mullaly, Sarah C, Kindrachuk, Jason, Jenssen, Havard, Hancock, Robert E. W

“…With the rapid rise in the incidence of multidrug resistant infections, there is substantial interest in host defense peptides as templates for production of…”
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The Evolution of Longitudinal Strain Across Various Univentricular Morphologies Prior to Superior Cavopulmonary Anastomosis by Buddhavarapu, Amulya, Chauhan, Dhaval, Erickson, Lori A., Elliott, Melissa D., Warren, Matthew, Forsha, Daniel E.

“…Infants with single-ventricle physiology have increased morbidity, mortality, and ventricular dysfunction in the pre–superior cavopulmonary anastomosis…”
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MIR142 Loss-of-Function Mutations Derepress ASH1L to Increase HOXA Gene Expression and Promote Leukemogenesis by Trissal, Maria C, Wong, Terrence N, Yao, Juo-Chin, Ramaswamy, Rahul, Kuo, Iris, Baty, Jack, Sun, Yaping, Jih, Gloria, Parikh, Nishi, Berrien-Elliott, Melissa M, Fehniger, Todd A, Ley, Timothy J, Maillard, Ivan, Reddy, Pavan R, Link, Daniel C

“…Point mutations in the seed sequence of miR-142-3p are present in a subset of acute myelogenous leukemia (AML) and in several subtypes of B-cell lymphoma…”
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