Search Results - "Elliott, M"

Mammalian phospholipase C by Kadamur, Ganesh, Ross, Elliott M

“…Phospholipase C (PLC) converts phosphatidylinositol 4,5-bisphosphate (PIP(2)) to inositol 1,4,5-trisphosphate (IP(3)) and diacylglycerol (DAG). DAG and IP(3)…”
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Precision medicine in cardiology by Antman, Elliott M., Loscalzo, Joseph

“…Key Points Precision medicine is an evolving strategy for disease prevention and tailored treatment that incorporates individual genetic, environmental, and…”
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Managing Stable Ischemic Heart Disease by Antman, Elliott M, Braunwald, Eugene

“…The preferred contemporary approach to the management of stable ischemic heart disease, also referred to as chronic coronary syndrome, 1 is not well defined…”
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Autophagy is required and protects against apoptosis during myoblast differentiation by McMillan, Elliott M, Quadrilatero, Joe

“…Several degradative systems assist in formation of multinucleated terminally differentiated myotubes. However, the role of autophagy in this process has not…”
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Evaluating the Cardiovascular Safety of Nonsteroidal Anti-Inflammatory Drugs by Antman, Elliott M

“…Some drugs used to treat noncardiovascular conditions may adversely impact the cardiovascular status of individuals both with and without known cardiovascular…”
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Binder jet 3D printing—Process parameters, materials, properties, modeling, and challenges by Mostafaei, Amir, Elliott, Amy M., Barnes, John E., Li, Fangzhou, Tan, Wenda, Cramer, Corson L., Nandwana, Peeyush, Chmielus, Markus

“…As a non-beam-based additive manufacturing (AM) method, binder jet 3D printing (BJ3DP) is a process in which a liquid binder is jetted on layers of powdered…”
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LRRK2 activation controls the repair of damaged endomembranes in macrophages by Herbst, Susanne, Campbell, Philip, Harvey, John, Bernard, Elliott M, Papayannopoulos, Venizelos, Wood, Nicholas W, Morris, Huw R, Gutierrez, Maximiliano G

“…Cells respond to endolysosome damage by either repairing the damage or targeting damaged endolysosomes for degradation via lysophagy. However, the signals…”
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NLRP12 senses heme and PAMPs to drive necrotic cell death and inflammation by Bernard, Elliott M, Broz, Petr

“…Red blood cell rupture (hemolysis) activates innate immunity and inflammation by releasing heme. Sundaram et al. implicate the immune sensor NLRP12 in…”
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Pooling Data From Individual Clinical Trials in the COVID-19 Era by Petkova, Eva, Antman, Elliott M, Troxel, Andrea B

“…This Viewpoint proposes principles and processes to allow pooling of individual patient data from clinical trials given decelerating participant recruitment at…”
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Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials by Ruff, Christian T, Dr, Giugliano, Robert P, MD, Braunwald, Eugene, Prof, Hoffman, Elaine B, PhD, Deenadayalu, Naveen, MPH, Ezekowitz, Michael D, Prof, Camm, A John, Prof, Weitz, Jeffrey I, Prof, Lewis, Basil S, Prof, Parkhomenko, Alexander, Prof, Yamashita, Takeshi, Prof, Antman, Elliott M, Prof

“…Summary Background Four new oral anticoagulants compare favourably with warfarin for stroke prevention in patients with atrial fibrillation; however, the…”
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Isotopic composition of passively collected nitrogen dioxide emissions: Vehicle, soil and livestock source signatures by Felix, J. David, Elliott, Emily M.

“…Quantifying contributions of local and regional NOx emission sources is an important initial step towards accurately assessing improvements in NOx emission…”
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Evolving concepts in dilated cardiomyopathy by Merlo, Marco, Cannatà, Antonio, Gobbo, Marco, Stolfo, Davide, Elliott, Perry M., Sinagra, Gianfranco

“…Dilated cardiomyopathy (DCM) represents a particular aetiology of systolic heart failure that frequently has a genetic background and usually affects young…”
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Activation and manipulation of inflammasomes and pyroptosis during bacterial infections by Bernard, Elliott M, Broz, Petr

“…Following detection of pathogen infection and disrupted cellular homeostasis, cells can activate a range of cell death pathways, such as apoptosis, necroptosis…”
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The Aspirin-NSAID Interaction: More Data, But a Lack of Clarity Remains by Antman, Elliott M.

“…[Display omitted]…”
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Isotopic advances in understanding reactive nitrogen deposition and atmospheric processing by Elliott, Emily M., Yu, Zhongjie, Cole, Amanda S., Coughlin, Justin G.

“…Recent advances in stable isotope measurements now allow for detailed investigations of the sources, transformations, and deposition of reactive nitrogen (N)…”
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Full Coverage for Preventive Medications after Myocardial Infarction by Choudhry, Niteesh K, Avorn, Jerry, Glynn, Robert J, Antman, Elliott M, Schneeweiss, Sebastian, Toscano, Michele, Reisman, Lonny, Fernandes, Joaquim, Spettell, Claire, Lee, Joy L, Levin, Raisa, Brennan, Troyen, Shrank, William H

“…In this trial, eliminating copayments for medications after hospitalization for MI did not reduce the primary outcome (first major vascular event or…”
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Improving care at the population and individual level: lessons from SWEDEHEART by Antman, Elliott M

“…Abstract…”
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Valvular Heart Disease Patients on Edoxaban or Warfarin in the ENGAGE AF-TIMI 48 Trial by De Caterina, Raffaele, MD, PhD, Renda, Giulia, MD, PhD, Carnicelli, Anthony P., MD, Nordio, Francesco, PhD, Trevisan, Marco, MSc, Mercuri, Michele F., MD, Ruff, Christian T., MD, MPH, Antman, Elliott M., MD, Braunwald, Eugene, MD, Giugliano, Robert P., MD, SM

“…Abstract Background The use of non-vitamin K antagonist oral anticoagulants (NOACs) instead of vitamin K antagonists (VKAs) in patients with atrial…”
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The Introduction and Clinical Use of Cardiac‐Specific Troponin Assays by Antman, Elliott M.

“…The earliest biomarkers introduced to diagnose myocardial infarction (MI) such as aspartate aminotransferase (AST) and lactic dehydrogenase (LDH) lacked…”
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Interfibrillar shear stress is the loading mechanism of collagen fibrils in tendon by Szczesny, Spencer E., Elliott, Dawn M.

“…[Display omitted] Despite the critical role tendons play in transmitting loads throughout the musculoskeletal system, little is known about the microstructural…”
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