Search Results - "Ellingrod, V."

Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Tricyclic Antidepressants by Hicks, J K, Swen, J J, Thorn, C F, Sangkuhl, K, Kharasch, E D, Ellingrod, V L, Skaar, T C, Müller, D J, Gaedigk, A, Stingl, J C

“…Polymorphisms in CYP2D6 and CYP2C19 affect the efficacy and safety of tricyclics, with some drugs being affected by CYP2D6 only, and others by both polymorphic…”
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Endothelial nitric oxide synthetase genetic variants, metabolic syndrome and endothelial function in schizophrenia by Burghardt, KJ, Grove, TB, Ellingrod, VL

“…Objective: The increasing rates of metabolic syndrome and cardiovascular disease in schizophrenia led to investigation into their causes, including atypical…”
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Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update by Hicks, J K, Sangkuhl, K, Swen, J J, Ellingrod, V L, Müller, D J, Shimoda, K, Bishop, J R, Kharasch, E D, Skaar, T C, Gaedigk, A, Dunnenberger, H M, Klein, T E, Caudle, K E, Stingl, J C

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Aberrant Brain Signal Variability and COMT Genotype in Chronic TMD Patients by Lim, M., Nascimento, T.D., Kim, D.J., Ellingrod, V.L., DaSilva, A.F.

“…The analysis of brain signal variability is a promising approach to understand pathological brain function related to chronic pain. This study investigates…”
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µ-Opioid Activity in Chronic TMD Pain Is Associated with COMT Polymorphism by Nascimento, T.D., Yang, N., Salman, D., Jassar, H., Kaciroti, N., Bellile, E., Danciu, T., Koeppe, R., Stohler, C., Zubieta, J.K., Ellingrod, V., DaSilva, A.F.

“…Clinicians have the dilemma of prescribing opioid or nonopioid analgesics to chronic pain patients; however, the impact of pain on our endogenous µ-opioid…”
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Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update by Hicks, JK, Sangkuhl, K, Swen, JJ, Ellingrod, VL, Müller, DJ, Shimoda, K, Bishop, JR, Kharasch, ED, Skaar, TC, Gaedigk, A, Dunnenberger, HM, Klein, TE, Caudle, KE, Stingl, JC

“…CYP2D6 and CYP2C19 polymorphisms affect the exposure, efficacy and safety of tricyclic antidepressants (TCAs), with some drugs being affected by CYP2D6 only…”
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The influence of metabolic syndrome, physical activity and genotype on catechol-O-methyl transferase promoter-region methylation in schizophrenia by Lott, S A, Burghardt, P R, Burghardt, K J, Bly, M J, Grove, T B, Ellingrod, V L

“…The catechol-O-methyl transferase ( COMT) 158Val/Met variant has been suggested to play a role in COMT function. Epigenetic regulation of COMT may further…”
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Pooled Analysis of Antidepressant Levels in Lactating Mothers, Breast Milk, and Nursing Infants by Weissman, Alicia M., Levy, Barcey T., Hartz, Arthur J., Bentler, Suzanne, Donohue, Micca, Ellingrod, Vicki L., Wisner, Katherine L.

“…OBJECTIVE: The available data on antidepressant levels in nursing infants were analyzed in order to calculate average infant drug levels and determine what…”
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IL-6 is associated with metabolic syndrome in bipolar disorder by Prossin, A, McInnis, M, Zalcman, S, Ellingrod, V

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The Influence of the Brain-Derived Neurotropic Factor Val66Met -Genotype and HMG-CoA Reductase Inhibitors on Insulin Resistance in the Schizophrenia and Bipolar Populations by Burghardt, K.J., Pop-Busui, R., Bly, M.J., Grove, T.B., Taylor, S.F., Ellingrod, V.L.

“…Introduction: The brain‐derived neurotrophic factor (BDNF) Val66Met variant and HMG‐COA reductase inhibitors (statins) have been implicated in insulin…”
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Venlafaxine: a heterocyclic antidepressant by Ellingrod, V L, Perry, P J

“…The pharmacology, pharmacokinetics, and clinical efficacy of venlafaxine hydrochloride, a new antidepressant, are described. Venlafaxine inhibits the reuptake…”
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Pharmacotherapy of Primary Obsessive-Compulsive Disorder: Review of the Literature by Ellingrod, Vicki L.

“…Obsessive‐compulsive disorder (OCD) is a chronic illness that affects 2–3% of Americans during their lifetime. It is characterized by recurrent obtrusive…”
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Nefazodone: a new antidepressant by Ellingrod, V L, Perry, P J

“…The chemistry, pharmacology, pharmacokinetics, and clinical efficacy of nefazodone hydrochloride, a new antidepressant, are described. Nefazodone enhances…”
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Abnormal Movements and Tardive Dyskinesia in Smokers and Nonsmokers with Schizophrenia Genotyped for Cytochrome P450 2D6 by Ellingrod, Vicki L., Schultz, Susan K., Arndt, Stephan

“…Study Objective. To investigate the relationships between cytochrome P450 (CYP) 2D6 genotype, antipsychotic drug exposure, abnormal movements and tardive…”
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Lack of menstrual cycle effects on hypothalamic‐ pituitary‐adrenal axis response to insulin‐induced hypoglycaemia by Long, Teresa D., Ellingrod, Vicki L., Kathol, Roger G., Christensen, Laura E., Resch, David S., Perry, Paul J.

“…Summary OBJECTIVE Limited data are available on the effects of the menstrual cycle on the hypothalamic‐pituitary‐adrenal axis (HPA) function. This study…”
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Pharmacogenetic screening for susceptibility to fetal malformations in women by Van Dyke, DC, Ellingrod, VL, Berg, MJ, Niebyl, , JR, Sherbondy, AL, Trembath, DG

“…OBJECTIVE: To present a review of the literature and research on the pharmacogenetics of congenital defects, with a focus on the need for predictive maternal…”
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Risk factors associated with metabolic syndrome in bipolar and schizophrenia subjects treated with antipsychotics: the role of folate pharmacogenetics by Ellingrod, Vicki L, Taylor, Stephan F, Dalack, Gregory, Grove, Tyler B, Bly, Michael J, Brook, Robert D, Zöllner, Sebastian K, Pop-Busui, Rodica

“…Folate has been implicated in cardiovascular disease with atypical antipsychotic (AAPs) use, and individuals with methylenetetrahydrofolate reductase (MTHFR)…”
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The association between risk factors for tardive dyskinesia and phenylalanine-induced abnormal movements in schizophrenia by Schultz, S. K., Ellingrod, V., Fleming, F. W., Andreasen, N. C.

“…We examined whether an oral challenge dose of the amino acid phenylalanine (a dopamine precursor) exacerbates the abnormal movements of tardive dyskinesia…”
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Association between cytochrome P4502D6 (CYP2D6) genotype, antipsychotic exposure, and abnormal involuntary movement scale (AIMS) score by Ellingrod, V L, Schultz, S K, Arndt, S

“…Antipsychotic metabolism cosegregates with the polymorphic cytochrome P4502D6 (CYP2D6) hepatic enzyme. Approximately 5-10% of Caucasians show impaired…”
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Comparison of Risperidone with Olanzapine in Elderly Patients with Dementia and Psychosis by Ellingrod, Vicki L., Schultz, Susan K., Ekstam-Smith, Karen, Kutscher, Eric, Turvey, Carolyn, Arndt, Stephan

“…Study Objectives. To compare the effects of risperidone and olanzapine on cognition in elderly patients with dementia and psychosis, and to compare the side…”
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