Search Results - "Eller, Leigh Anne"

Systematic comparison of HIV-1 Envelope-specific IgG responses induced by different vaccination regimens: Can we steer IgG recognition towards regions of viral vulnerability? by Horvath, Augusta, Rogers, Lisa, Pollakis, Georgios, Baranov, Olga, Pieroth, Nora, Joseph, Sarah, Chachage, Mkunde, Heitzer, Asli, Maganga, Lucas, Msafiri, Frank, Joachim, Agricola, Viegas, Edna, Eller, Leigh-Anne, Kibuuka, Hannah, Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Nitayapan, Sorachai, Dhitavat, Jittima, Premsri, Nakorn, Fidler, Sarah, Shattock, Robin J, Robb, Merlin Lee, Weber, Jonathan, McCormack, Sheena, Munseri, Patricia Jane, Lyamuya, Eligius, Nilsson, Charlotta, Kroidl, Arne, Hoelscher, Michael, Wagner, Ralf, Geldmacher, Christof, Held, Kathrin

“…Immunogens and vaccination regimens can influence patterns of immune-epitope recognition, steering them towards or away from epitopes of potential viral…”
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A Phase 1/2 Study of a Multiclade HIV-1 DNA Plasmid Prime and Recombinant Adenovirus Serotype 5 Boost Vaccine in HIV-Uninfected East Africans (RV 172) by Kibuuka, Hannah, Kimutai, Robert, Maboko, Leonard, Sawe, Fred, Schunk, Mirjam S., Kroidl, Arne, Shaffer, Douglas, Eller, Leigh Anne, Kibaya, Rukia, Eller, Michael A., Schindler, Karin B., Schuetz, Alexandra, Millard, Monica, Kroll, Jason, Dally, Len, Hoelscher, Michael, Bailer, Robert, Cox, Josephine H., Marovich, Mary, Birx, Deborah L., Graham, Barney, Michael, Nelson L., de Souza, Mark S., Robb, Merlin L.

“…Background. Human immunodeficiency virus (HIV) vaccine development remains a global priority. We describe the safety and immunogenicity of a multiclade DNA…”
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Human Immunodeficiency Virus Type 1 Infection Is Associated with Increased NK Cell Polyfunctionality and Higher Levels of KIR3DL1+ NK Cells in Ugandans Carrying the HLA-B Bw4 Motif by ELLER, Michael A, KOEHLER, Rebecca N, CURRIER, Jeffrey R, SANDBERG, Johan K, KIJAK, Gustavo H, ANNE ELLER, Leigh, GUWATUDDE, David, MAROVICH, Mary A, MICHAEL, Nelson L, DE SOUZA, Mark S, WABWIRE-MANGEN, Fred, ROBB, Merlin L

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Long-term sequelae after Ebola virus disease in Bundibugyo, Uganda: a retrospective cohort study by Clark, Danielle V, Dr, Kibuuka, Hannah, MD, Millard, Monica, MPH, Wakabi, Salim, MD, Lukwago, Luswa, MPH, Taylor, Alison, BS, Eller, Michael A, PhD, Eller, Leigh Anne, PhD, Michael, Nelson L, MD, Honko, Anna N, PhD, Olinger, Gene G, PhD, Schoepp, Randal J, PhD, Hepburn, Matthew J, MD, Hensley, Lisa E, PhD, Robb, Merlin L, MD

“…Summary Background The limited data available for long-term Ebola virus disease health outcomes suggest that sequelae persist for longer than 1 year after…”
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Protective Efficacy of a Global HIV-1 Mosaic Vaccine against Heterologous SHIV Challenges in Rhesus Monkeys by Barouch, Dan H., Stephenson, Kathryn E., Borducchi, Erica N., Smith, Kaitlin, Stanley, Kelly, McNally, Anna G., Liu, Jinyan, Abbink, Peter, Maxfield, Lori F., Seaman, Michael S., Dugast, Anne-Sophie, Alter, Galit, Ferguson, Melissa, Li, Wenjun, Earl, Patricia L., Moss, Bernard, Giorgi, Elena E., Szinger, James J., Eller, Leigh Anne, Billings, Erik A., Rao, Mangala, Tovanabutra, Sodsai, Sanders-Buell, Eric, Weijtens, Mo, Pau, Maria G., Schuitemaker, Hanneke, Robb, Merlin L., Kim, Jerome H., Korber, Bette T., Michael, Nelson L.

“…The global diversity of HIV-1 represents a critical challenge facing HIV-1 vaccine development. HIV-1 mosaic antigens are bioinformatically optimized…”
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HIV virologic failure and its predictors among HIV-infected adults on antiretroviral therapy in the African Cohort Study by Kiweewa, Francis, Esber, Allahna, Musingye, Ezra, Reed, Domonique, Crowell, Trevor A, Cham, Fatim, Semwogerere, Michael, Namagembe, Rosemary, Nambuya, Alice, Kafeero, Cate, Tindikahwa, Allan, Eller, Leigh Anne, Millard, Monica, Gelderblom, Huub C, Keshinro, Babajide, Adamu, Yakubu, Maswai, Jonah, Owuoth, John, Sing'oei, Valentine Chepkorir, Maganga, Lucas, Bahemana, Emmanuel, Khamadi, Samoel, Robb, Merlin L, Ake, Julie A, Polyak, Christina S, Kibuuka, Hannah

“…The 2016 WHO consolidated guidelines on the use of antiretroviral drugs defines HIV virologic failure for low and middle income countries (LMIC) as plasma…”
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Evolution of Antibody Responses in HIV-1 CRF01_AE Acute Infection: Founder Envelope V1V2 Impacts the Timing and Magnitude of Autologous Neutralizing Antibodies by Kuriakose Gift, Syna, Wieczorek, Lindsay, Sanders-Buell, Eric, Zemil, Michelle, Molnar, Sebastian, Donofrio, Gina, Townsley, Samantha, Chenine, Agnes L, Bose, Meera, Trinh, Hung V, Barrows, Brittani M, Sriplienchan, Somchai, Kitsiripornchai, Suchai, Nitayapan, Sorachai, Eller, Leigh-Anne, Rao, Mangala, Ferrari, Guido, Michael, Nelson L, Ake, Julie A, Krebs, Shelly J, Robb, Merlin L, Tovanabutra, Sodsai, Polonis, Victoria R

“…Understanding the dynamics of early immune responses to HIV-1 infection, including the evolution of initial neutralizing and antibody-dependent cellular…”
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Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection by Lal, Kerri G., Kim, Dohoon, Costanzo, Margaret C., Creegan, Matthew, Leeansyah, Edwin, Dias, Joana, Paquin-Proulx, Dominic, Eller, Leigh Anne, Schuetz, Alexandra, Phuang-ngern, Yuwadee, Krebs, Shelly J., Slike, Bonnie M., Kibuuka, Hannah, Maganga, Lucas, Nitayaphan, Sorachai, Kosgei, Josphat, Sacdalan, Carlo, Ananworanich, Jintanat, Bolton, Diane L., Michael, Nelson L., Shacklett, Barbara L., Robb, Merlin L., Eller, Michael A., Sandberg, Johan K.

“…Mucosa-associated invariant T (MAIT) cell loss in chronic HIV-1 infection is a significant insult to antimicrobial immune defenses. Here we investigate the…”
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Safety and immunogenicity of Ebola virus and Marburg virus glycoprotein DNA vaccines assessed separately and concomitantly in healthy Ugandan adults: a phase 1b, randomised, double-blind, placebo-controlled clinical trial by Kibuuka, Hannah, MMed, Berkowitz, Nina M, MPH, Millard, Monica, MPH, Enama, Mary E, MA, Tindikahwa, Allan, MPH, Sekiziyivu, Arthur B, MSc, Costner, Pamela, BSN, Sitar, Sandra, MS, Glover, Deline, BS, Hu, Zonghui, PhD, Joshi, Gyan, MPH, Stanley, Daphne, MS, Kunchai, Meghan, MPH, Eller, Leigh Anne, PhD, Bailer, Robert T, PhD, Koup, Richard A, MD, Nabel, Gary J, MD, Mascola, John R, MD, Sullivan, Nancy J, PhD, Graham, Barney S, MD, Roederer, Mario, PhD, Michael, Nelson L, MD, Robb, Merlin L, MD, Ledgerwood, Julie E, Dr

“…Summary Background Ebola virus and Marburg virus cause serious disease outbreaks with high case fatality rates. We aimed to assess the safety and…”
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Expansion of Stem Cell-Like CD4 + Memory T Cells during Acute HIV-1 Infection Is Linked to Rapid Disease Progression by Pušnik, Jernej, Eller, Michael A, Tassaneetrithep, Boonrat, Schultz, Bruce T, Eller, Leigh Anne, Nitayaphan, Sorachai, Kosgei, Josphat, Maganga, Lucas, Kibuuka, Hannah, Alter, Galit, Michael, Nelson L, Robb, Merlin L, Streeck, Hendrik

“…Acute HIV-1 infection is characterized by high viremia and massive depletion of CD4 T cells throughout all tissue compartments. During this time the latent…”
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HIV incidence and its associated factors among young adults with multiple sexual partners in Maputo, Mozambique: a vaccine preparedness study by Macicame, Ivalda, Bhatt, Nilesh, Viegas, Edna, Yates, Adam, Nwoga, Chiaka, Chissumba, Raquel Matavele, Monteiro, Vanessa, Imbach, Michelle, Milazzo, Mark, Li, Qun, Schech, Steven, Mebrahtu, Tsedal, Eller, Leigh Anne, Swann, Edith, Michael, Nelson L, Robb, Merlin L, Crowell, Trevor A, Polyak, Christina S, Jani, Ilesh

“…Sub-Saharan Africa has a high burden of HIV, particularly among female sex workers (FSW) and men who have sex with men (MSM). Future clinical trials to…”
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Molecular dating and viral load growth rates suggested that the eclipse phase lasted about a week in HIV-1 infected adults in East Africa and Thailand by Rolland, Morgane, Tovanabutra, Sodsai, Dearlove, Bethany, Li, Yifan, Owen, Christopher L, Lewitus, Eric, Sanders-Buell, Eric, Bose, Meera, O'Sullivan, AnneMarie, Rossenkhan, Raabya, Labuschagne, Jan Phillipus Lourens, Edlefsen, Paul T, Reeves, Daniel B, Kijak, Gustavo, Miller, Shana, Poltavee, Kultida, Lee, Jenica, Bonar, Lydia, Harbolick, Elizabeth, Ahani, Bahar, Pham, Phuc, Kibuuka, Hannah, Maganga, Lucas, Nitayaphan, Sorachai, Sawe, Fred K, Eller, Leigh Anne, Gramzinski, Robert, Kim, Jerome H, Michael, Nelson L, Robb, Merlin L

“…Most HIV-1 infected individuals do not know their infection dates. Precise infection timing is crucial information for studies that document transmission…”
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Effect of Human Immunodeficiency Virus Type 1 (HIV-1) Subtype on Disease Progression in Persons from Rakai, Uganda, with Incident HIV-1 Infection by Kiwanuka, Noah, Laeyendecker, Oliver, Robb, Merlin, Kigozi, Godfrey, Arroyo, Miguel, McCutchan, Francine, Eller, Leigh Anne, Eller, Michael, Makumbi, Fred, Birx, Deborah, Wabwire-Mangen, Fred, Serwadda, David, Sewankambo, Nelson K., Quinn, Thomas C., Wawer, Maria, Gray, Ronald

“…Background. Human immunodeficiency virus type 1 (HIV-1) subtypes differ in biological characteristics that may affect pathogenicity. Methods. We determined the…”
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HIV-1 infections with multiple founders associate with the development of neutralization breadth by Lewitus, Eric, Townsley, Samantha M, Li, Yifan, Donofrio, Gina C, Dearlove, Bethany L, Bai, Hongjun, Sanders-Buell, Eric, O'Sullivan, Anne Marie, Bose, Meera, Kibuuka, Hannah, Maganga, Lucas, Nitayaphan, Sorachai, Sawe, Fredrick K, Eller, Leigh Anne, Michael, Nelson L, Polonis, Victoria R, Ake, Julie A, Vasan, Sandhya, Robb, Merlin L, Tovanabutra, Sodsai, Krebs, Shelly J, Rolland, Morgane

“…Eliciting broadly neutralizing antibodies (bnAbs) is a cornerstone of HIV-1 vaccine strategies. Comparing HIV-1 envelope (env) sequences from the first weeks…”
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Safety and Immunogenicity of PENNVAX-G DNA Prime Administered by Biojector 2000 or CELLECTRA Electroporation Device With Modified Vaccinia Ankara-CMDR Boost by Ake, Julie A., Schuetz, Alexandra, Pegu, Poonam, Wieczorek, Lindsay, Eller, Michael A., Kibuuka, Hannah, Sawe, Fredrick, Maboko, Leonard, Polonis, Victoria, Karasavva, Nicos, Weiner, David, Sekiziyivu, Arthur, Kosgei, Josphat, Missanga, Marco, Kroidl, Arne, Mann, Philipp, Ratto-Kim, Silvia, Eller, Leigh Anne, Earl, Patricia, Moss, Bernard, Dorsey-Spitz, Julie, Milazzo, Mark, Ouedraogo, G. Laissa, Rizvi, Farrukh, Yan, Jian, Khan, Amir S., Peel, Sheila, Sardesai, Niranjan Y., Michael, Nelson L., Ngauy, Viseth, Marovich, Mary, Robb, Merlin L.

“…In this phase 1 human immunodeficiency virus vaccine trial of PENNVAX-G DNA, administered by Biojector 2000 or CELLECTRA electroporation device, boosted by…”
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Clinical laboratory reference values in adults in Kisumu County, Western Kenya; hematology, chemistry and CD4 by Sing'oei, Valentine, Ochola, Jew, Owuoth, John, Otieno, June, Rono, Eric, Andagalu, Ben, Otieno, Lucas, Nwoga, Chiaka, Copeland, Nathanial K, Lawlor, John, Yates, Adam, Imbach, Michelle, Crowell, Trevor A, Eller, Leigh Anne, Kamau, Edwin, Modjarrad, Kayvon, Cowden, Jessica, Ake, Julie, Robb, Merlin L, Polyak, Christina S

“…Clinical laboratory reference intervals (RIs) are essential for diagnosing and managing patients in routine clinical care as well as establishing eligibility…”
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Associations Between Antibody Fc-Mediated Effector Functions and Long-Term Sequelae in Ebola Virus Survivors by Paquin-Proulx, Dominic, Gunn, Bronwyn M., Alrubayyi, Aljawharah, Clark, Danielle V., Creegan, Matthew, Kim, Dohoon, Kibuuka, Hannah, Millard, Monica, Wakabi, Salim, Eller, Leigh Anne, Michael, Nelson L., Schoepp, Randal J., Hepburn, Matthew J., Hensley, Lisa E., Robb, Merlin L., Alter, Galit, Eller, Michael A.

“…Antibodies that mediate non-neutralizing functions play an important role in the immune response to Ebola virus (EBOV) and are thought to impact disease…”
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Evolution of HIV-1 within untreated individuals and at the population scale in Uganda by Raghwani, Jayna, Redd, Andrew D, Longosz, Andrew F, Wu, Chieh-Hsi, Serwadda, David, Martens, Craig, Kagaayi, Joseph, Sewankambo, Nelson, Porcella, Stephen F, Grabowski, Mary K, Quinn, Thomas C, Eller, Michael A, Eller, Leigh Anne, Wabwire-Mangen, Fred, Robb, Merlin L, Fraser, Christophe, Lythgoe, Katrina A

“…HIV-1 undergoes multiple rounds of error-prone replication between transmission events, resulting in diverse viral populations within and among individuals. In…”
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HIV prevalence and risk behavior among male and female adults screened for enrolment into a vaccine preparedness study in Maputo, Mozambique by Macicame, Ivalda, Bhatt, Nilesh, Matavele Chissumba, Raquel, Eller, Leigh Anne, Viegas, Edna, Araújo, Khelvon, Nwoga, Chiaka, Li, Qun, Milazzo, Mark, Hills, Nancy K, Lindan, Christina, Michael, Nelson L, Robb, Merlin L, Jani, Ilesh, Polyak, Christina S

“…Mozambique continues to have a significant burden of HIV. Developing strategies to control the HIV epidemic remains a key priority for the Mozambican public…”
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Determining hematological, biochemical and immunological reference values in healthy adults with high-risk for HIV acquisition in Mozambique by Cumbane, Victória, Imbach, Michelle, Chissumba, Raquel Matavele, Macicame, Ivalda, Eller, Leigh Anne, Lawlor, John, Milazzo, Mark, Li, Qun, Crowell, Trevor, Mutombene, Mirna, Guiliche, Onélia, Viegas, Edna, Nwoga, Chiaka, Yates, Adam, Michael, Nelson, Robb, Merlin, Polyak, Christina S, Jani, Ilesh V, Bhatt, Nilesh

“…In many African countries, laboratory reference values are not established for the local healthy adult population. In Mozambique, reference values are known…”
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