Search Results - "Ell, Brian"

Tumor-Induced Osteoclast miRNA Changes as Regulators and Biomarkers of Osteolytic Bone Metastasis by Ell, Brian, Mercatali, Laura, Ibrahim, Toni, Campbell, Neil, Schwarzenbach, Heidi, Pantel, Klaus, Amadori, Dino, Kang, Yibin

“…Understanding the mechanism by which tumor cells influence osteoclast differentiation is crucial for improving treatment of osteolytic metastasis. Here, we…”
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Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization by Korpal, Manav, Ell, Brian J, Buffa, Francesca M, Ibrahim, Toni, Blanco, Mario A, Celià-Terrassa, Toni, Mercatali, Laura, Khan, Zia, Goodarzi, Hani, Hua, Yuling, Wei, Yong, Hu, Guohong, Garcia, Benjamin A, Ragoussis, Jiannis, Amadori, Dino, Harris, Adrian L, Kang, Yibin

“…The miR200 family regulates EMT through E-cadherin modulation and has been proposed to contribute to metastasis thusly. This report identifies a promoting role…”
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Hysteresis control of epithelial-mesenchymal transition dynamics conveys a distinct program with enhanced metastatic ability by Celià-Terrassa, Toni, Bastian, Caleb, Liu, Daniel D., Ell, Brian, Aiello, Nicole M., Wei, Yong, Zamalloa, Jose, Blanco, Andres M., Hang, Xiang, Kunisky, Dmitriy, Li, Wenyang, Williams, Elizabeth D., Rabitz, Herschel, Kang, Yibin

“…Epithelial-mesenchymal transition (EMT) have been extensively characterized in development and cancer, and its dynamics have been modeled as a non-linear…”
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Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling by Shen, Minhong, Jiang, Yi-Zhou, Wei, Yong, Ell, Brian, Sheng, Xinlei, Esposito, Mark, Kang, Jooeun, Hang, Xiang, Zheng, Hanqiu, Rowicki, Michelle, Zhang, Lanjing, Shih, Weichung J., Celià-Terrassa, Toni, Liu, Yirong, Cristea, IIeana, Shao, Zhi-Ming, Kang, Yibin

“…Triple-negative breast cancer (TNBC) patients have the worst prognosis and distant metastasis-free survival among all major subtypes of breast cancer. The poor…”
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The MicroRNA-23b/27b/24 Cluster Promotes Breast Cancer Lung Metastasis by Targeting Metastasis-suppressive Gene Prosaposin by Ell, Brian, Qiu, Qiong, Wei, Yong, Mercatali, Laura, Ibrahim, Toni, Amadori, Dino, Kang, Yibin

“…MicroRNAs (miRNAs) have been shown to function as key regulators of tumor progression and metastasis. Recent studies have indicated that the miRNAs comprising…”
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Vascular endothelial‐cadherin stimulates syndecan‐1‐coupled insulin‐like growth factor‐1 receptor and cross‐talk between αVβ3 integrin and vascular endothelial growth factor receptor 2 at the onset of endothelial cell dissemination during angiogenesis by Rapraeger, Alan C., Ell, Brian J., Roy, Madhuchhanda, Li, Xuehui, Morrison, Orrianne R., Thomas, Grant M., Beauvais, DeannaLee M.

“…Vascular endothelial growth factor (VEGF)‐stimulated angiogenesis depends on a cross‐talk mechanism involving VEGF receptor 2 (VEGFR2), vascular endothelial…”
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Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells by Celià-Terrassa, Toni, Meca-Cortés, Oscar, Mateo, Francesca, Martínez de Paz, Alexia, Rubio, Nuria, Arnal-Estapé, Anna, Ell, Brian J, Bermudo, Raquel, Díaz, Alba, Guerra-Rebollo, Marta, Lozano, Juan José, Estarás, Conchi, Ulloa, Catalina, Álvarez-Simón, Daniel, Milà, Jordi, Vilella, Ramón, Paciucci, Rosanna, Martínez-Balbás, Marian, de Herreros, Antonio García, Gomis, Roger R, Kang, Yibin, Blanco, Jerónimo, Fernández, Pedro L, Thomson, Timothy M

“…Malignant progression in cancer requires populations of tumor-initiating cells (TICs) endowed with unlimited self renewal, survival under stress, and…”
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Author Correction: Hysteresis control of epithelial-mesenchymal transition dynamics conveys a distinct program with enhanced metastatic ability by Celià-Terrassa, Toni, Bastian, Caleb, Liu, Daniel D., Ell, Brian, Aiello, Nicole M., Wei, Yong, Zamalloa, Jose, Blanco, Andres M., Hang, Xiang, Kunisky, Dmitriy, Li, Wenyang, Williams, Elizabeth D., Rabitz, Herschel, Kang, Yibin

“…The original version of this Article contained an error in the spelling of the author Daniel D. Liu, which was incorrectly given as Daniel Liu. This has now…”
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MicroRNAs as regulators of bone homeostasis and bone metastasis by Ell, Brian, Kang, Yibin

“…MicroRNAs (miRNAs) are short, endogenous RNAs that have essential roles in regulating gene expression through the disruption of target genes. The miRNA-induced…”
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Transcriptional control of cancer metastasis by Ell, Brian, Kang, Yibin

“…Highlights • Transcription factors (TFs) are key players and therapeutic targets in metastasis. • Oncogenic and tumor-suppressive TFs can also affect…”
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SnapShot: Bone Metastasis by Ell, Brian, Kang, Yibin

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Syndecan-1 regulates αvβ3 and αvβ5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor by Beauvais, DeannaLee M., Ell, Brian J., McWhorter, Andrea R., Rapraeger, Alan C.

“…Syndecan-1 (Sdc1) is a matrix receptor shown to associate via its extracellular domain with the αvβ3 and αvβ5 integrins, potentially regulating cell adhesion,…”
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MicroRNAs as regulators of tumor-associated stromal cells by Ell, Brian, Kang, Yibin

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Skin Immuno-CometChip in 3D vs. 2D Cultures to Screen Topical Toxins and Skin-Specific Cytochrome Inducers by Rosenthal, Dean S, Kuo, Li-Wei, Seagrave, Sarah L, Soni, Vikas, Islam, Nusrat, Minsky, Geetanjali, Dussan-Cuellar, Lucia, Ell, Brian, Simbulan-Rosenthal, Cynthia M, Sykora, Peter

“…The targets of topical genotoxic agents are basal and stem cells of the skin. These cells may misrepair DNA lesions, resulting in deleterious mutations of…”
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Vascular endothelial-cadherin stimulates syndecan-1-coupled insulin-like growth factor-1 receptor and cross-talk between [alpha]V[beta]3 integrin and vascular endothelial growth factor receptor 2 at the onset of endothelial cell dissemination during angiogenesis by Rapraeger, Alan C, Ell, Brian J, Roy, Madhuchhanda, Li, Xuehui, Morrison, Orrianne R, Thomas, Grant M, Beauvais, DeannaLee M

“…Vascular endothelial growth factor (VEGF)-stimulated angiogenesis depends on a cross-talk mechanism involving VEGF receptor 2 (VEGFR2), vascular endothelial…”
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VE-cadherin Stimulates Syndecan-1-Coupled IGF1R and Cross-Talk between alphaVbeta3 Integrin and VEGFR2 During the Onset of Endothelial Cell Dissemination in Angiogenesis by Rapraeger, Alan C., Ell, Brian J., Roy, Madhuchhanda, Li, Xuehui, Morrison, Orrianne R., Thomas, Grant M., Beauvais, DeannaLee M.

“…VEGF-stimulated angiogenesis depends on a cross-talk mechanism involving VEGF receptor 2 (VEGFR2), vascular endothelial (VE)-cadherin and the αVβ3 integrin…”
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Tumor-intrinsic and -extrinsic mechanisms in breast cancer metastasis by Ell, Brian

“…In breast cancer, mortality is predominantly associated with metastasis, cancerous spread to distant organs. Understanding tumor dissemination is vitally…”
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Syndecan-1 regulates I- sub(v)I2 sub(3) and I- sub(v)I2 sub(5) integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor by Beauvais, DeannaLee M, Ell, Brian J, McWhorter, Andrea R, Rapraeger, Alan C

“…Syndecan-1 (Sdc1) is a matrix receptor shown to associate via its extracellular domain with the I- sub(v)I2 sub(3) and I- sub(v)I2 sub(5) integrins,…”
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Syndecan-1 regulates α v β 3 and α v β 5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor by Beauvais, DeannaLee M., Ell, Brian J., McWhorter, Andrea R., Rapraeger, Alan C.

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Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells by Celia-Terrassa, Toni, Meca-Cortes, Oscar, Mateo, Francesca, De Paz, Alexia Martinez, Rubio, Nuria, Arnal-Estape, Anna, Ell, Brian J, Bermudo, Raquel, Diaz, Alba, Guerra-Rebollo, Marta, Lozano, Juan Jose, Estaras, Conchi, Ulloa, Catalina, Alvarez-Simon, Daniel, Mila, Jordi, Vilella, Ramon, Paciucci, Rosanna, Martinez-Balbas, Marian, De Herreros, Antonio Garcia, Gomis, Roger R, Kang, Yibin, Blanco, Jeronimo, Fernondez, Pedro L, Thomson, Timothy M

“…Malignant progression in cancer requires populations of tumor-initiating cells (TICs) endowed with unlimited self renewal, survival under stress, and…”
Get full text