Search Results - "Elkordy, Amal Ali"
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Liposomal Drug Delivery Systems and Anticancer Drugs
Published in Molecules (Basel, Switzerland) (14-04-2018)“…Cancer is a life-threatening disease contributing to ~3.4 million deaths worldwide. There are various causes of cancer, such as smoking, being overweight or…”
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A review of emerging technologies enabling improved solid oral dosage form manufacturing and processing
Published in Advanced drug delivery reviews (01-11-2021)“…Emerging technologies enabling improved solid oral dosage form manufacturing and processing. [Display omitted] Tablets are the most widely utilized solid oral…”
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Evaluation of novel cationic gene based liposomes with cyclodextrin prepared by thin film hydration and microfluidic systems
Published in Scientific reports (22-10-2019)“…In gene delivery, non-viral vectors have become the preferred carrier system for DNA delivery. They can overcome major viral issues such as immunogenicity and…”
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Brief Insights into mRNA Vaccines: Their Successful Production and Nanoformulation for Effective Response against COVID-19 and Their Potential Success for Influenza A and B
Published in Pathogens (Basel) (12-06-2024)“…A mRNA vaccine is a type of vaccine that induces an immune response. Antigen-encoding mRNA is delivered via vaccine carriers into the immune cells, which are…”
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An Overview of the Antioxidant Effects of Ascorbic Acid and Alpha Lipoic Acid (in Liposomal Forms) as Adjuvant in Cancer Treatment
Published in Antioxidants (25-04-2020)“…Antioxidants are known to minimize oxidative stress by interacting with free radicals produced as a result of cell aerobic reactions. Oxidative stress has long…”
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Insights into Asymmetric Liposomes as a Potential Intervention for Drug Delivery Including Pulmonary Nanotherapeutics
Published in Pharmaceutics (15-01-2023)“…Liposome-based drug delivery systems are nanosized spherical lipid bilayer carriers that can encapsulate a broad range of small drug molecules (hydrophilic and…”
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The Effects of Hydration Parameters and Co-Surfactants on Methylene Blue-Loaded Niosomes Prepared by the Thin Film Hydration Method
Published in Pharmaceuticals (Basel, Switzerland) (29-03-2019)“…This work aimed to investigate and optimise the effects of co-surfactants, hydration volume, and time on the entrapment of methylene blue (MB) within niosomes…”
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Liposomal Drug Delivery against Helicobacter pylori Using Furazolidone and N-Acetyl Cysteine in Augmented Therapy
Published in Pharmaceutics (26-08-2024)“…( ) infection is a significant global health concern, affecting approximately 50% of the world's population and leading to gastric ulcers, gastritis, and…”
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Brief on Recent Application of Liposomal Vaccines for Lower Respiratory Tract Viral Infections: From Influenza to COVID-19 Vaccines
Published in Pharmaceuticals (Basel, Switzerland) (17-11-2021)“…Vaccination is the most effective means of preventing infectious diseases and saving lives. Modern biotechnology largely enabled vaccine development. In the…”
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Brief Effect of a Small Hydrophobic Drug (Cinnarizine) on the Physicochemical Characterisation of Niosomes Produced by Thin-Film Hydration and Microfluidic Methods
Published in Pharmaceutics (13-10-2018)“…Novel niosomal formulations containing cinnarizine were developed to enhance its drug characteristics. In this work, niosomes (non-ionic surfactant vesicles)…”
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Liposomes and Their Therapeutic Applications in Enhancing Psoriasis and Breast Cancer Treatments
Published in Nanomaterials (Basel, Switzerland) (01-11-2024)“…Psoriasis and breast cancer are two examples of diseases where associated inflammatory pathways within the body’s immune system are implicated. Psoriasis is a…”
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Dendrimers-Based Drug Delivery System: A Novel Approach in Addressing Parkinson’s Disease
Published in Future pharmacology (01-12-2022)“…Parkinson’s disease (PD) is a progressive neurodegenerative disease that is characterized by the loss of dopamine. Since dopamine has trouble entering the…”
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Combination of lactose (as a carrier) with Cremophor® EL (as a liquid vehicle) to enhance dissolution of griseofulvin
Published in Powder technology (01-09-2013)“…Liquisolid technique is an approach to enhance dissolution of hydrophobic drugs. Most of liquisolid formulations are prepared with microcrystalline cellulose…”
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Design and evaluation of effervescent floating tablets based on hydroxyethyl cellulose and sodium alginate using pentoxifylline as a model drug
Published in Drug design, development and therapy (01-01-2015)“…The aim of this work was to design and evaluate effervescent floating gastro-retentive drug delivery matrix tablets with sustained-release behavior using a…”
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Feasibility of Using Gluconolactone, Trehalose and Hydroxy-Propyl Gamma Cyclodextrin to Enhance Bendroflumethiazide Dissolution Using Lyophilisation and Physical Mixing Techniques
Published in Pharmaceutics (01-02-2018)“…Hydrophobic drugs are facing a major challenge in dissolution rate enhancement and solubility in aqueous solutions; therefore, a variety of methods have been…”
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In vitro characterisation of Span 65 niosomal formulations containing proteins
Published in Current drug delivery (01-01-2015)“…Proteins can be encapsulated in niosomes as they are known to protect proteins against the surrounding environment. Niosomes of Span 65/cholesterol/pluronic F…”
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Insights into the Influences of Carboxymethyl-β-Cyclodextrin on DNA Formulations Characteristics and Gene Transfection Efficiency
Published in Current drug delivery (01-01-2018)“…Gene therapy is an expanding field and it can treat genetic and acquired diseases. It was found that formulations with DNA: CM-β-CD…”
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Fabrication and physicochemical characterisation of novel pimozide loaded PLGA nanoparticles
Published in British Journal of Pharmacy (17-04-2019)“…Cancer has always been a big concern for human health. There is always an increased need for fabrication of newer drugs or repurposing existing drugs to treat…”
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Effects of preparation methods on the characteristics of niosomes
Published in British Journal of Pharmacy (17-04-2019)“…Niosomes are colloidal vesicles capable of encapsulating drugs as a carrier for drug delivery systems. They are formed by self-assembly of a non-ionic…”
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Preparation, characterisation and cell transfection of cationic liposomes in gene therapy
Published in British Journal of Pharmacy (17-04-2019)“…Cationic lipid-mediated gene transfer is one of the most commonly used non-viral vectors. It has been shown to be a safe and effective carrier. However, its…”
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