Search Results - "Elkord, E."

In‐vitro effect of pembrolizumab on different T regulatory cell subsets by Toor, S. M., Syed Khaja, A. S., Alkurd, I., Elkord, E.

“…Summary Programmed death‐1 (PD‐1) and interactions with PD‐ligand 1 (PD‐L1) play critical roles in the tumour evasion of immune responses through different…”
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Phase II trial of imiquimod and HPV therapeutic vaccination in patients with vulval intraepithelial neoplasia by Daayana, S, Elkord, E, Winters, U, Pawlita, M, Roden, R, Stern, P L, Kitchener, H C

“…Background: Vulval intraepithelial neoplasia (VIN) is a premalignant condition, which is frequently associated with type HPV16 infection, and multifocal…”
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Effect of pembrolizumab on CD4+CD25+, CD4+LAP+ and CD4+TIM‐3+ T cell subsets by Toor, S. M., Sasidharan Nair, V., Pfister, G., Elkord, E.

“…Summary Tumor immune evasion involves the expansion of avidly proliferating immunosuppressive cells and inhibition of effector T cell proliferation. Immune…”
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A combination of T regulatory cell-specific markers to determine the expanded subsets in cancer patients by Elkord, E, Abd Al Samid, M, Chaudhary, B, Yazan, K, Ammori, B

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Immunology and immunotherapy approaches for prostate cancer by Elkord, E

“…Several mechanisms that impair the immune response to promote tumour progression are reported. These mechanisms aim to reduce the ability of antigen-presenting…”
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Novel therapeutic strategies by regulatory T cells in allergy by Elkord, E

“…Natural CD4+CD25+FoxP3+ regulatory T cells (Treg) actively suppress physiological and pathological responses, therefore playing a critical role in controlling…”
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Novel IFNγ ELISPOT Assay for Detection of Functional Carcinoembryonic Antigen‐Specific Chimeric Antigen Receptor‐Redirected T Cells by Elkord, E., Burt, D. J.

“…We here describe the development of a novel ELISPOT assay for the detection and enumeration of IFNγ‐secreting functional chimeric antigen receptor…”
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5T4 oncofetal antigen is expressed in high risk of relapse childhood pre-B acute lymphoblastic leukemia and is associated with a more invasive and chemotactic phenotype by Castro, F V, McGinn, O J, Krishnan, S, Marinov, G, Li, J, Rutkowski, A J, Elkord, E, Burt, D J, Holland, M, Vaghjiani, R, Gallego, A, Saha, V, Stern, P L

“…Although the overall prognosis in childhood acute lymphoblastic leukemia (ALL) is good, outcome after relapse is poor. Recurrence is frequently characterized…”
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Frequency of human T regulatory cells in peripheral blood is significantly reduced by cryopreservation by Elkord, Eyad

“…Cryopreservation of peripheral blood mononuclear cells (PBMC) is essential for many clinical and research assays. Some studies reported consistent changes in…”
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An MVA based vaccine targeting the oncofoetal antigen 5T4 in patients undergoing surgical resection of colorectal cancer liver metastases by Stern, P.L, Elkord, E, Dangoor, A, Drury, N.L, Harrop, R, Burt, D.J, Drifjhout, J.W, Naylor, S, Sherlock, D, Hawkins, R.E

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900 - A combination of T regulatory cell-specific markers to determine the expanded subsets in cancer patients by Elkord, E., Abd Al Samid, M., Chaudhary, B., Yazan, K., Ammori, B.

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5-AZA treatment induces cytotoxicity and in vitro expression of immunogenic NY-ESO-1 antigen in non-small lung cancer cell NCI-H1975 by Inchakalody, V.P., Taleb, S., Sherif, S., Fernandes, Q., Sahir, F., Sivaraman, S.K., Khan, A.Q., Nair, V. Sasidharan, Ashi, E.A.A., Al-Zaidan, L.S., Iskandarani, A., Krishnankutty, R., Therachiyil, L., Raza, A., Merhi, M., Uddin, S., Elkord, E., Dermime, S.

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Enhancing NY-ESO-1 antigen expression in lung cancer cells through gene hypomethylation using 5-Aza-2′-deoxycytidine by Dermime, S., Inchakalody, V., Nair, V., El-Ashi, A., Taleb, S., Fernandes, Q., Al-Zaidan, L., Iskandarani, A., Sivaraman, S., Sahir, F., Krishnankutty, R., Therachiyil, L., Merhi, M., Raza, A., Uddin, S., Elkord, E., Knuth, A.

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103PEnhancing NY-ESO-1 antigen expression in lung cancer cells through gene hypomethylation using 5-Aza-2′-deoxycytidine by Dermime, S, Inchakalody, V, Nair, V, El-Ashi, A, Taleb, S, Fernandes, Q, Al-Zaidan, L, Iskandarani, A, Sivaraman, S, Sahir, F, Krishnankutty, R, Therachiyil, L, Merhi, M, Raza, A, Uddin, S, Elkord, E, Knuth, A

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Human monocyte isolation methods influence cytokine production from in vitro generated dendritic cells by Elkord, Eyad, Williams, Paul E., Kynaston, Howard, Rowbottom, Anthony W.

“…Summary There is growing interest in the in vitro generation of dendritic cells (DC) from peripheral blood monocytes, but the effect of the method chosen to…”
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An MVA-based vaccine targeting the oncofetal antigen 5T4 in patients undergoing surgical resection of colorectal cancer liver metastases by Elkord, Eyad, Dangoor, Adam, Drury, Noel L, Harrop, Richard, Burt, Deborah J, Drijfhout, Jan W, Hamer, Caroline, Andrews, Danielle, Naylor, Stuart, Sherlock, David, Hawkins, Robert E, Stern, Peter L

“…We investigated the use of a therapeutic vaccine, TroVax in patients undergoing surgical resection of colorectal cancer liver metastases. Systemic immunity…”
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Correlation between CD8 super(+) T cells specific for prostate-specific antigen and level of disease in patients with prostate cancer by Elkord, E, Rowbottom, A W, Kynaston, H, Williams, P E

“…Modest work has been performed to improve the sensitivity of residual disease detection or investigate the contribution that the immune system makes in…”
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Correlation between CD8+ T cells specific for prostate-specific antigen and level of disease in patients with prostate cancer by Elkord, Eyad, Rowbottom, Anthony W., Kynaston, Howard, Williams, Paul E.

“…Modest work has been performed to improve the sensitivity of residual disease detection or investigate the contribution that the immune system makes in…”
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CD4 super(+) T-cell recognition of human 5T4 oncofoetal antigen: implications for initial depletion of CD25 super(+) T cells by Elkord, Eyad, Burt, Deborah J, Drijfhout, Jan W, Hawkins, Robert E, Stern, Peter L

“…Background: The human 5T4 (h5T4) oncofoetal antigen is expressed by a wide variety of human carcinomas including colorectal, ovarian, gastric and renal, but…”
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Differential CTLs specific for prostate-specific antigen in healthy donors and patients with prostate cancer by Elkord, Eyad, Williams, Paul E., Kynaston, Howard, Rowbottom, Anthony W.

“…Induction of CTL responses specific for prostate-specific antigen (PSA)-derived peptides in healthy individuals and patients with prostate cancer (PC) was…”
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