Search Results - "Elkomy, Mohammed H."

Polymeric Nanoparticles for Delivery of Natural Bioactive Agents: Recent Advances and Challenges by Elmowafy, Mohammed, Shalaby, Khaled, Elkomy, Mohammed H, Alsaidan, Omar Awad, Gomaa, Hesham A M, Abdelgawad, Mohamed A, Mostafa, Ehab M

“…In the last few decades, several natural bioactive agents have been widely utilized in the treatment and prevention of many diseases owing to their unique and…”
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Changing the Drug Delivery System: Does It Add to Non-Compliance Ramifications Control? A Simulation Study on the Pharmacokinetics and Pharmacodynamics of Atypical Antipsychotic Drug by Elkomy, Mohammed H

“…This study investigates the pharmacokinetic (PK) and pharmacodynamic (PD) consequences of shifting from Quetiapine fumarate immediate-release (IR) to…”
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Surface-Modified Bilosomes Nanogel Bearing a Natural Plant Alkaloid for Safe Management of Rheumatoid Arthritis Inflammation by Elkomy, Mohammed H, Alruwaili, Nabil K, Elmowafy, Mohammed, Shalaby, Khaled, Zafar, Ameeduzzafar, Ahmad, Naveed, Alsalahat, Izzeddin, Ghoneim, Mohammed M, Eissa, Essam M, Eid, Hussein M

“…Rheumatoid arthritis (RA) is a chronic inflammatory illness affecting the joints. The characteristic of RA is gradual joint deterioration. Current RA treatment…”
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Lipid Nanocarriers Overlaid with Chitosan for Brain Delivery of Berberine via the Nasal Route by Abo El-Enin, Hadel A, Elkomy, Mohammed H, Naguib, Ibrahim A, Ahmed, Marwa F, Alsaidan, Omar A, Alsalahat, Izzeddin, Ghoneim, Mohammed M, Eid, Hussein M

“…This research aimed to design, optimize, and evaluate berberine-laden nanostructured lipid carriers overlaid with chitosan (BER-CTS-NLCs) for efficient brain…”
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Berberine Encapsulated Lecithin–Chitosan Nanoparticles as Innovative Wound Healing Agent in Type II Diabetes by Panda, Dibya Sundar, Eid, Hussein M., Elkomy, Mohammed H., Khames, Ahmed, Hassan, Randa M., Abo El-Ela, Fatma I., Yassin, Heba A.

“…The aim of this research is to formulate a lecithin–chitosan based nanoparticulate system loaded with berberine (BER-LC-CTS-NPs) that could be integrated into…”
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Role of ADMA/DDAH-1 and iNOS/eNOS signaling in the gastroprotective effect of tadalafil against indomethacin-induced gastric injury by Mohamed, Yasmin T., Naguib, Ibrahim A., Abo-Saif, Ali A., Elkomy, Mohammed H., Alghamdi, Badrah S., Mohamed, Wafaa R.

“…Non-steroidal anti-inflammatory drugs (NSAIDs)-induced gastric ulcers represent a significant clinical concern and adversely affect the quality of life…”
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Quality by design (QbD) based development and validation of bioanalytical RP-HPLC method for dapagliflozin: Forced degradation and preclinical pharmacokinetic study by Ameeduzzafar, El-Bagory, Ibrahim, Alruwaili, Nabil K., Imam, Syed Sarim, Alomar, Fadhel Ahmed, Elkomy, Mohammed H., Ahmad, Naveed, Elmowafy, Mohammed

“…A rapid, sensitive, and reliable quality by design (QbD) based bioanalytical HPLC method was developed and validated for quantification of dapagliflozin (DFG)…”
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Bilosomes as a promising nanoplatform for oral delivery of an alkaloid nutraceutical: improved pharmacokinetic profile and snowballed hypoglycemic effect in diabetic rats by Elkomy, Mohammed H., Eid, Hussein M., Elmowafy, Mohammed, Shalaby, Khaled, Zafar, Ameeduzzafar, Abdelgawad, Mohamed A., Rateb, Mostafa E., Ali, Mohammed R.A., Alsalahat, Izzeddin, Abou-Taleb, Heba A.

“…Diabetes mellitus is a life-threatening metabolic disease. At the moment, there is no effective treatment available to combat it. In this study, we aimed to…”
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Intranasal Delivery of Granisetron to the Brain via Nanostructured Cubosomes-Based In Situ Gel for Improved Management of Chemotherapy-Induced Emesis by Eissa, Essam M., Elkomy, Mohammed H., Eid, Hussein M., Ali, Adel A., Abourehab, Mohammed A. S., Alsubaiyel, Amal M., Naguib, Ibrahim A., Alsalahat, Izzeddin, Hassan, Amira H.

“…This research aimed to boost granisetron (GS) delivery to the brain via the intranasal route to better manage chemotherapy-induced emesis. Glycerol monooleate…”
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Innovative pulmonary targeting of terbutaline sulfate-laded novasomes for non-invasive tackling of asthma: statistical optimization and comparative in vitro/in vivo evaluation by Elkomy, Mohammed H., El Menshawe, Shahira F., Kharshoum, Rasha M., Abdeltwab, Amany M., Hussein, Raghda R. S., Hamad, Doaa S., Alsalahat, Izzeddin, Aboud, Heba M.

“…Asthma represents a globally serious non-communicable ailment with significant public health outcomes for both pediatrics and adults triggering vast morbidity…”
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Development of thermosensitive hydrogel of Amphotericin-B and Lactoferrin combination-loaded PLGA-PEG-PEI nanoparticles for potential eradication of ocular fungal infections: In-vitro , ex-vivo and in-vivo studies by Elhabal, Sammar Fathy, Ghaffar, Shrouk A, Hager, Raghda, Elzohairy, Nahla A, Khalifa, Mohamed Mansour, Mohie, Passant M, Gad, Rania A, Omar, Nasreen N, Elkomy, Mohammed H, Khasawneh, Mohammad Ahmad, Abdelaal, Nashwa

“…The most prevalent conditions among ocular surgery and COVID-19 patients are fungal eye infections, which may cause inflammation and dry eye, and may cause…”
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Loratadine bioavailability via buccal transferosomal gel: formulation, statistical optimization, in vitro/in vivo characterization, and pharmacokinetics in human volunteers by Elkomy, Mohammed H., El Menshawe, Shahira F., Abou-Taleb, Heba A., Elkarmalawy, Marwa H.

“…Loratadine (LTD) is an antihistaminic drug that suffers limited solubility, poor oral bioavailability (owing to extensive first-pass metabolism), and highly…”
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Fabrication and In Vitro/In Vivo Appraisal of Metronidazole Intra-Gastric Buoyant Sustained-Release Tablets in Healthy Volunteers by Elkomy, Mohammed H, Abou-Taleb, Heba A, Eid, Hussein M, Yassin, Heba A

“…is thought to be the most common cause of peptic and duodenal ulcers. Eradication of this organism is now considered one of the lines of treatment of gastric…”
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Intratracheally Inhalable Nifedipine-Loaded Chitosan-PLGA Nanocomposites as a Promising Nanoplatform for Lung Targeting: Snowballed Protection via Regulation of TGF-β/β-Catenin Pathway in Bleomycin-Induced Pulmonary Fibrosis by Elkomy, Mohammed H, Khallaf, Rasha A, Mahmoud, Mohamed O, Hussein, Raghda R S, El-Kalaawy, Asmaa M, Abdel-Razik, Abdel-Razik H, Aboud, Heba M

“…Pulmonary fibrosis is a serious ailment that may progress to lung remodeling and demolition, where the key participants in its incidence are fibroblasts…”
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Pharmacokinetics and placental transfer of magnesium sulfate in pregnant women by Brookfield, Kathleen F., MD, PhD, MPH, Su, Felice, MD, Elkomy, Mohammed H., PhD, Drover, David R., MD, Lyell, Deirdre J., MD, Carvalho, Brendan, MBBCh, FRCA

“…Background Magnesium sulfate is one of the most commonly prescribed intravenous medications in obstetrics. Despite its widespread use, there are limited data…”
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Arabinoxylan-Carboxymethylcellulose Composite Films for Antibiotic Delivery to Infected Wounds by Alruwaili, Nabil K, Ahmad, Naveed, Alzarea, Abdulaziz I, Alomar, Fadhel A, Alquraini, Ali, Akhtar, Sultan, Shahari, Muhammad Syafiq Bin, Zafar, Ameeduzzafar, Elmowafy, Mohammed, Elkomy, Mohammed H, Dolzhenko, Anton V, Iqbal, Mohammad Saeed

“…Modern dressings should provide for local delivery of antibiotics and protect the wound from bacterial infection, dehydration and environmental factors to…”
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Antibiotic-Loaded Psyllium Husk Hemicellulose and Gelatin-Based Polymeric Films for Wound Dressing Application by Ahmad, Naveed, Ahmad, Muhammad Masood, Alruwaili, Nabil K, Alrowaili, Ziyad Awadh, Alomar, Fadhel Ahmed, Akhtar, Sultan, Alsaidan, Omar Awad, Alhakamy, Nabil A, Zafar, Ameeduzzafar, Elmowafy, Mohammed, Elkomy, Mohammed H

“…Wound infections are one of the major reasons for the delay in the healing of chronic wounds and can be overcome by developing effective wound dressings…”
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Intranasal Nanotransferosomal Gel for Quercetin Brain Targeting: I. Optimization, Characterization, Brain Localization, and Cytotoxic Studies by Elkomy, Mohammed H, Zaki, Randa Mohammed, Alsaidan, Omar A, Elmowafy, Mohammed, Zafar, Ameeduzzafar, Shalaby, Khaled, Abdelgawad, Mohamed A, Abo El-Ela, Fatma I, Rateb, Mostafa E, Naguib, Ibrahim A, Eid, Hussein M

“…Numerous neurological disorders have a pathophysiology that involves an increase in free radical production in the brain. Quercetin (QER) is a nutraceutical…”
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Intranasal Nanotransferosomal Gel for Quercetin Brain Targeting: II. Antidepressant Effect in an Experimental Animal Model by Elkomy, Mohammed H, Abo El-Ela, Fatma I, Zaki, Randa Mohammed, Alsaidan, Omar A, Elmowafy, Mohammed, Zafar, Ameeduzzafar, Shalaby, Khaled, Abdelgawad, Mohamed A, Omar, Hany A, Salama, Rania, Eid, Hussein M

“…Depression is a serious mental disorder and the most prevalent cause of disability and suicide worldwide. Quercetin (QER) demonstrated antidepressant effects…”
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Tunable Polymeric Mixed Micellar Nanoassemblies of Lutrol F127/Gelucire 44/14 for Oral Delivery of Praziquantel: A Promising Nanovector against Hymenolepis nana in Experimentally-Infected Rats by Arafa, Waleed M., Elkomy, Mohammed H., Aboud, Heba M., Ali, Mona Ibrahim, Abdel Gawad, Samah S., Aboelhadid, Shawky M., Mahdi, Emad A., Alsalahat, Izzeddin, Abdel-Tawab, Heba

“…Hymenolepiasis represents a parasitic infection of common prevalence in pediatrics with intimidating impacts, particularly amongst immunocompromised patients…”
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