Search Results - "Elizabeth Joubert"
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Multi-stakeholder value creation and appropriation from food-related health claims
Published in South African Journal of Science (01-05-2024)“…Health claims are considered a means to add value to food and beverages; however, it is not always evident which stakeholders benefit and to what extent they…”
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Healthy or Not Healthy? A Mixed-Methods Approach to Evaluate Front-of-Pack Nutrition Labels as a Tool to Guide Consumers
Published in Nutrients (08-07-2022)“…This study explored how South African food labels could be improved, to enhance customer evaluation of the overall healthiness of packaged food. Focus was…”
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Cyclopia intermedia (Honeybush) Induces Uncoupling Protein 1 and Peroxisome Proliferator-Activated Receptor Alpha Expression in Obese Diabetic Female db/db Mice
Published in International journal of molecular sciences (15-02-2023)“…Previously, we reported that a crude polyphenol-enriched fraction of (CPEF), a plant consumed as the herbal tea, commonly known as honeybush, reduced lipid…”
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Anti-Inflammatory Effects of Aspalathus linearis and Cyclopia spp. Extracts in a UVB/Keratinocyte (HaCaT) Model Utilising Interleukin-1α Accumulation as Biomarker
Published in Molecules (Basel, Switzerland) (02-10-2016)“…Ultraviolet B (UVB) radiation is one of the major predisposing risk factors of skin cancer. The anticancer and photoprotective effects of unoxidized rooibos (…”
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Comprehensive phenolic profiling of Cyclopia genistoides (L.) Vent. by LC-DAD-MS and -MS/MS reveals novel xanthone and benzophenone constituents
Published in Molecules (Basel, Switzerland) (07-08-2014)“…A high-performance liquid chromatographic (HPLC) method coupled with diode-array detection (DAD) was optimized for the qualitative analysis of aqueous extracts…”
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High-temperature oxidation reduces the bitterness of honeybush infusions depending on changes in phenolic composition
Published in Food science & technology (01-03-2021)“…Honeybush tea infusions, especially those prepared from Cyclopia genistoides, can be unacceptably bitter, given the association of this herbal tea with sweet…”
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Bitter Taste Impact and Thermal Conversion of a Naringenin Glycoside from Cyclopia genistoides
Published in Journal of natural products (Washington, D.C.) (28-12-2018)“…A naringenin derivative, isolated from Cyclopia genistoides, a bitter tasting herbal tea, especially when in green (unoxidized) form, was identified as…”
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Therapeutic effects of an aspalathin-rich green rooibos extract, pioglitazone and atorvastatin combination therapy in diabetic db/db mice
Published in PloS one (13-05-2021)“…Oral therapeutics used to treat type 2 diabetes and cardiovascular disease often fail to prevent the progression of disease and their comorbidities. Rooibos…”
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New Insights into the Efficacy of Aspalathin and Other Related Phytochemicals in Type 2 Diabetes-A Review
Published in International journal of molecular sciences (29-12-2021)“…In the pursuit of bioactive phytochemicals as a therapeutic strategy to manage metabolic risk factors for type 2 diabetes (T2D), aspalathin, -glucosyl…”
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Hyperglycemia-induced oxidative stress and heart disease-cardioprotective effects of rooibos flavonoids and phenylpyruvic acid-2- O -β-D-glucoside
Published in Nutrition & metabolism (10-07-2017)“…Diabetic patients are at an increased risk of developing heart failure when compared to their non-diabetic counter parts. Accumulative evidence suggests…”
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Aspalathin-Enriched Green Rooibos Extract Reduces Hepatic Insulin Resistance by Modulating PI3K/AKT and AMPK Pathways
Published in International journal of molecular sciences (01-02-2019)“…We previously demonstrated that an aspalathin-enriched green rooibos extract (GRE) reversed palmitate-induced insulin resistance in C2C12 skeletal muscle and…”
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Co-pigmentation of Pinotage anthocyanins with Cyclopia (honeybush) polyphenols in model wine solutions
Published in Food chemistry advances (01-12-2023)“…•Cyclopia subternata polyphenols can act as co-pigments for Pinotage anthocyanins.•A xanthone-enriched fraction (F2) exerted the strongest co-pigmentation…”
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Inhibitory Interactions of Aspalathus linearis (Rooibos) Extracts and Compounds, Aspalathin and Z-2-(β-d-Glucopyranosyloxy)-3-phenylpropenoic Acid, on Cytochromes Metabolizing Hypoglycemic and Hypolipidemic Drugs
Published in Molecules (Basel, Switzerland) (12-11-2016)“…Rooibos extract, due to its glucose and lipid lowering effects, has potential as a nutraceutical for improvement of metabolic dysfunction. Potential herb-drug…”
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Aspalathin Protects the Heart against Hyperglycemia-Induced Oxidative Damage by Up-Regulating Nrf2 Expression
Published in Molecules (Basel, Switzerland) (14-01-2017)“…Aspalathin (ASP) can protect H9c2 cardiomyocytes against high glucose (HG)-induced shifts in myocardial substrate preference, oxidative stress, and apoptosis…”
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Phenolic content and antioxidant activity of rooibos food ingredient extracts
Published in Journal of food composition and analysis (01-08-2012)“…Hot water extracts of the herbal tea, rooibos, are increasingly used as an ingredient in ready-to-drink beverages and a variety of food products. The quantity…”
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Adipose tissue as a possible therapeutic target for polyphenols: A case for Cyclopia extracts as anti-obesity nutraceuticals
Published in Biomedicine & pharmacotherapy (01-12-2019)“…[Display omitted] Obesity is a significant contributor to increased morbidity and premature mortality due to increasing the risk of many chronic metabolic…”
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Aspalathin, a natural product with the potential to reverse hepatic insulin resistance by improving energy metabolism and mitochondrial respiration
Published in PloS one (02-05-2019)“…Aspalathin is a rooibos flavonoid with established blood glucose lowering properties, however, its efficacy to moderate complications associated with hepatic…”
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Aspalathin improves glucose and lipid metabolism in 3T3‐L1 adipocytes exposed to palmitate
Published in Molecular nutrition & food research (01-11-2015)“…SCOPE: Saturated‐free fatty acids, such as palmitate, are associated with insulin resistance. This study aimed to establish if an aspalathin‐enriched green…”
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Aspalathin-Rich Green Rooibos Extract Lowers LDL-Cholesterol and Oxidative Status in High-Fat Diet-Induced Diabetic Vervet Monkeys
Published in Molecules (Basel, Switzerland) (02-05-2019)“…Type 2 diabetic patients possess a two to four fold-increased risk for Cardiovascular Diseases (CVD). Hyperglycemia, oxidative stress associated with…”
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Food ingredient extracts of Cyclopia subternata (Honeybush): variation in phenolic composition and antioxidant capacity
Published in Molecules (Basel, Switzerland) (07-12-2012)“…Cyclopia subternata plants are traditionally used for the production of the South African herbal tea, honeybush, and recently as aqueous extracts for the food…”
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