Search Results - "Elisabete Amaral de Moraes, Maria"
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Evidence for Host Epigenetic Signatures Arising From Arbovirus Infections: A Systematic Review
Published in Frontiers in immunology (31-05-2019)“…Arbovirus infections have steadily become a major pandemic threat. This study aimed at investigating the existence of host epigenetic markers arising from the…”
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Vasorelaxant and antihypertensive effects of methanolic fraction of the essential oil of Alpinia zerumbet
Published in Vascular pharmacology (01-05-2013)“…Abstract Alpinia zerumbet is used in folk medicine in Brazil to treat hypertension. However, several pathways involved in the mechanism of vasorelaxation are…”
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Clinical trial for uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): adverse effects approach
Published in Anais brasileiros de dermatología (01-06-2018)“…The Clinical Trial for Uniform Multidrug Therapy for Leprosy Patients in Brazil (U-MDT/CT-BR), designed to evaluate the effectiveness of a six-months regimen,…”
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The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected
Published in PloS one (16-02-2011)“…Based on pre-DNA racial/color methodology, clinical and pharmacological trials have traditionally considered the different geographical regions of Brazil as…”
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Innovative Burn Treatment Using Tilapia Skin as a Xenograft: A Phase II Randomized Controlled Trial
Published in Journal of burn care & research (02-05-2020)“…Skin substitutes are considered a useful alternative for occlusive dressings in the treatment of superficial burns as they reduce the frequency of dressing…”
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Brazilian clinical trial of uniform multidrug therapy for leprosy patients - the correlation between clinical disease types and adverse effects
Published in Memórias do Instituto Oswaldo Cruz (01-12-2012)“…This study sought to verify the correlation between leprosy types and the adverse effects of treatment drugs. This quantitative, prospective, nested study was…”
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1,4-Naphthoquinone (CNN1) Induces Apoptosis through DNA Damage and Promotes Upregulation of H2AFX in Leukemia Multidrug Resistant Cell Line
Published in International journal of molecular sciences (23-07-2022)“…The multidrug resistance (MDR) phenotype is one of the major obstacles in the treatment of chronic myeloid leukemia (CML) in advantage stages such as blast…”
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Targeting aurora kinases as a potential prognostic and therapeutical biomarkers in pediatric acute lymphoblastic leukaemia
Published in Scientific reports (04-12-2020)“…Aurora kinases (AURKA and AURKB) are mitotic kinases with an important role in the regulation of several mitotic events, and in hematological malignancies,…”
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Solid Tumors and Kinase Inhibition: Management and Therapy Efficacy Evolution
Published in International journal of molecular sciences (30-03-2022)“…The increasing numbers of cancer cases worldwide and the exceedingly high mortality rates of some tumor subtypes raise the question about if the current…”
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Circadian Rhythm Dysregulation and Leukemia Development: The Role of Clock Genes as Promising Biomarkers
Published in International journal of molecular sciences (01-08-2022)“…The circadian clock (CC) is a daily system that regulates the oscillations of physiological processes and can respond to the external environment in order to…”
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Recalculating the Route: Repositioning Antimicrobial Peptides for Cancer Treatment
Published in Chemistry & biodiversity (01-02-2024)“…Resistance to antimicrobial drugs has been considered a public health problem. Likewise, the increasing resistance of cancer cells to drugs currently used in…”
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Impact of Bariatric Surgery on the Pharmacokinetics Parameters of Amoxicillin
Published in Obesity surgery (01-03-2019)“…Background Bariatric surgery leads to several anatomo-physiological modifications that may affect pharmacokinetic parameters and consequently alter the…”
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13
Long-COVID olfactory dysfunction: allele E4 of apolipoprotein E as a possible protective factor
Published in Arquivos de neuro-psiquiatria (01-09-2024)“…Olfactory dysfunction (OD) represents a frequent manifestation of the coronavirus disease 2019 (COVID-19). Apolipoprotein E (APOE) is a protein that interacts…”
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Acute toxicity study of the isomeric mixture of alpha and beta amyrin from Protium heptaphyllum (Aubl.) Marchand
Published in Acta scientiarum. Biological sciences (27-10-2023)“…The isomeric mixture of alpha and beta amyrin (AMY), present in the resin of Protium heptaphyllum, is popularly used as anti-inflammatory and anti-ulcer. The…”
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Leukemic Stem Cell: A Mini-Review on Clinical Perspectives
Published in Frontiers in oncology (24-06-2022)“…Hematopoietic stem cells (HSCs) are known for their ability to proliferate and self-renew, thus being responsible for sustaining the hematopoietic system and…”
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The Role of WRAP53 in Cell Homeostasis and Carcinogenesis Onset
Published in Current issues in molecular biology (01-11-2022)“…The WD repeat containing antisense to TP53 (WRAP53) gene codifies an antisense transcript for tumor protein p53 (TP53), stabilization (WRAP53α), and a…”
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Lyophilised tilapia skin as a xenograft for superficial partial thickness burns: a novel preparation and storage technique
Published in Journal of wound care (02-10-2020)“…Despite a considerable decrease in its incidence worldwide, burns remain the fourth most common type of trauma. The majority of burns are small, with 75% of…”
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Kinase Inhibitor Screening Displayed ALK as a Possible Therapeutic Biomarker for Gastric Cancer
Published in Pharmaceutics (01-09-2022)“…Despite advances in cancer chemotherapy, gastric cancer (GC) continues to have high recurrence rates and poor prognosis with limited treatment options…”
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PARP1 Is Overexpressed in Hematological Malignant Cell Lines: A Framework for Experimental Oncology
Published in Anticancer research (01-05-2021)“…Experimental oncology commonly uses cells as oncological models, providing a framework for the testing of drugs, and investigation of cytotoxicity, mutagenesis…”
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Comparison of BCR-ABL Transcript Variants Between Patients With Chronic Myeloid Leukaemia and Leukaemia Cell Lines
Published in In vivo (Athens) (01-07-2019)“…Chronic myeloid leukaemia (CML) is a myeloproliferative disorder characterized by the presence of breakpoint cluster region-Abelson murine leukemia (BCR-ABL1)…”
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