Search Results - "Elisa Principi"

Mesenchymal Stem Cell‐Derived Extracellular Vesicles as Mediators of Anti‐Inflammatory Effects: Endorsement of Macrophage Polarization by Lo Sicco, Claudia, Reverberi, Daniele, Balbi, Carolina, Ulivi, Valentina, Principi, Elisa, Pascucci, Luisa, Becherini, Pamela, Bosco, Maria Carla, Varesio, Luigi, Franzin, Chiara, Pozzobon, Michela, Cancedda, Ranieri, Tasso, Roberta

“…Mesenchymal Stem Cells (MSCs) are effective therapeutic agents enhancing the repair of injured tissues mostly through their paracrine activity. Increasing…”
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Effects of 5-fluorouracil on morphology, cell cycle, proliferation, apoptosis, autophagy and ROS production in endothelial cells and cardiomyocytes by Focaccetti, Chiara, Bruno, Antonino, Magnani, Elena, Bartolini, Desirée, Principi, Elisa, Dallaglio, Katiuscia, Bucci, Eraldo O, Finzi, Giovanna, Sessa, Fausto, Noonan, Douglas M, Albini, Adriana

“…Antimetabolites are a class of effective anticancer drugs interfering in essential biochemical processes. 5-Fluorouracil (5-FU) and its prodrug Capecitabine…”
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eATP/P2X7R Axis: An Orchestrated Pathway Triggering Inflammasome Activation in Muscle Diseases by Panicucci, Chiara, Raffaghello, Lizzia, Bruzzone, Santina, Baratto, Serena, Principi, Elisa, Minetti, Carlo, Gazzerro, Elisabetta, Bruno, Claudio

“…In muscle ATP is primarily known for its function as an energy source and as a mediator of the "excitation-transcription" process, which guarantees muscle…”
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The effect of late-life environmental enrichment on stress and anxiety: The role of sex and age-related differences in coping with aversive stimuli by Balietti, Marta, Principi, Elisa, Giacomini, Luca, Giorgetti, Belinda, Conti, Fiorenzo

“…Anxiety significantly diminishes the quality of life in older adults, and the drugs used for its treatment often come with risky side effects…”
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Fenretinide (4-HPR) Targets Caspase-9, ERK 1/2 and the Wnt3a/β-Catenin Pathway in Medulloblastoma Cells and Medulloblastoma Cell Spheroids by Bassani, Barbara, Bartolini, Desirèe, Pagani, Arianna, Principi, Elisa, Zollo, Massimo, Noonan, Douglas M, Albini, Adriana, Bruno, Antonino

“…Medulloblastoma (MB), a neuroectodermal tumor arising in the cerebellum, represents the most frequent childhood brain malignancy. Current treatments for MB…”
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P2X7 Receptor Antagonist Reduces Fibrosis and Inflammation in a Mouse Model of Alpha-Sarcoglycan Muscular Dystrophy by Raffaghello, Lizzia, Principi, Elisa, Baratto, Serena, Panicucci, Chiara, Pintus, Sara, Antonini, Francesca, Del Zotto, Genny, Benzi, Andrea, Bruzzone, Santina, Scudieri, Paolo, Minetti, Carlo, Gazzerro, Elisabetta, Bruno, Claudio

“…Limb-girdle muscular dystrophy R3, a rare genetic disorder affecting the limb proximal muscles, is caused by mutations in the α-sarcoglycan gene (Sgca) and…”
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Systemic distribution of single-walled carbon nanotubes in a novel model: alteration of biochemical parameters, metabolic functions, liver accumulation, and inflammation in vivo by Principi, Elisa, Girardello, Rossana, Bruno, Antonino, Manni, Isabella, Gini, Elisabetta, Pagani, Arianna, Grimaldi, Annalisa, Ivaldi, Federico, Congiu, Terenzio, De Stefano, Daniela, Piaggio, Giulia, de Eguileor, Magda, Noonan, Douglas M, Albini, Adriana

“…The increasing use of carbon nanotubes (CNTs) in several industrial applications raises concerns on their potential toxicity due to factors such as tissue…”
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Environmental impact of multi-wall carbon nanotubes in a novel model of exposure: systemic distribution, macrophage accumulation, and amyloid deposition by Albini, Adriana, Pagani, Arianna, Pulze, Laura, Bruno, Antonino, Principi, Elisa, Congiu, Terenzio, Gini, Elisabetta, Grimaldi, Annalisa, Bassani, Barbara, De Flora, Silvio, de Eguileor, Magda, Noonan, Douglas M

“…Carbon nanotubes (CNTs) have been extensively investigated and employed for industrial use because of their peculiar physical properties, which make them ideal…”
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Interactions of single-wall carbon nanotubes with endothelial cells by Albini, Adriana, PhD, Mussi, Valentina, PhD, Parodi, Alessandro, PhD, Ventura, Agostina, PhD, Principi, Elisa, MS, Tegami, Sara, MS, Rocchia, Massimiliano, PhD, Francheschi, Enrico, PhD, Sogno, Ilaria, MS, Cammarota, Rosaria, MS, Finzi, Giovanna, MD, PhD, Sessa, Fausto, MD, Noonan, Douglas McClain, PhD, Valbusa, Ugo, PhD

“…Abstract Single-wall carbon nanotubes (SWCNTs) could be promising delivery vehicles for cancer therapy. These carriers are generally introduced intravenously,…”
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The role of the P2X7 receptor in myeloid-derived suppressor cells and immunosuppression by Principi, Elisa, Raffaghello, Lizzia

“…•Myeloid derived suppressor cells are immature myeloid cells with potent immunosuppressive activity.•Myeloid derived suppressor cells play an important role in…”
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LCN2 overexpression in bone enhances the hematopoietic compartment via modulation of the bone marrow microenvironment by Costa, Delfina, Principi, Elisa, Lazzarini, Edoardo, Descalzi, Fiorella, Cancedda, Ranieri, Castagnola, Patrizio, Tavella, Sara

“…Lipocalin‐2 (LCN2) is a member of the lipocalin family whose expression is modulated in several conditions, including cell differentiation, innate immunity,…”
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First Characterization of Human Amniotic Fluid Stem Cell Extracellular Vesicles as a Powerful Paracrine Tool Endowed with Regenerative Potential by Balbi, Carolina, Piccoli, Martina, Barile, Lucio, Papait, Andrea, Armirotti, Andrea, Principi, Elisa, Reverberi, Daniele, Pascucci, Luisa, Becherini, Pamela, Varesio, Luigi, Mogni, Massimo, Coviello, Domenico, Bandiera, Tiziano, Pozzobon, Michela, Cancedda, Ranieri, Bollini, Sveva

“…Human amniotic fluid stem cells (hAFS) have shown a distinct secretory profile and significant regenerative potential in several preclinical models of disease…”
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BV2-derived extracellular vesicles modulate microglia inflammatory profile, neuronal plasticity, and behavioural performances in late adult mice by Rinaldi, Arianna, Balietti, Marta, Principi, Elisa, De Luca, Mariassunta, De Felice, Eleonora, Narcisi, Francesca Michela, Vilardo, Laura, Rosito, Maria, Piacentini, Roberto, D’Alessandro, Giuseppina, D’Agnano, Igea, Maggi, Laura, Conti, Fiorenzo, Limatola, Cristina, Catalano, Myriam

“…[Display omitted] •Microglia-derived extracellular vesicles reduce the inflammatory phenotype of microglia in late adult male and female mice.•Extracellular…”
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Comprehensive Phenotyping of Peripheral Blood T Lymphocytes in Healthy Mice by Del Zotto, Genny, Principi, Elisa, Antonini, Francesca, Baratto, Serena, Panicucci, Chiara, Bruno, Claudio, Raffaghello, Lizzia

“…T lymphocytes play a central role in antigen‐specific immune responses. They modulate the function of different immune cells both through a direct contact…”
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Rebalancing expression of HMGB1 redox isoforms to counteract muscular dystrophy by Careccia, Giorgia, Saclier, Marielle, Tirone, Mario, Ruggieri, Elena, Principi, Elisa, Raffaghello, Lizzia, Torchio, Silvia, Recchia, Deborah, Canepari, Monica, Gorzanelli, Andrea, Ferrara, Michele, Castellani, Patrizia, Rubartelli, Anna, Rovere-Querini, Patrizia, Casalgrandi, Maura, Preti, Alessandro, Lorenzetti, Isabella, Bruno, Claudio, Bottinelli, Roberto, Brunelli, Silvia, Previtali, Stefano Carlo, Bianchi, Marco Emilio, Messina, Graziella, Vénéreau, Emilie

“…Muscular dystrophies (MDs) are a group of genetic diseases characterized by progressive muscle wasting associated to oxidative stress and persistent…”
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Proteomics profiling and machine learning in nusinersen-treated patients with spinal muscular atrophy by Panicucci, Chiara, Sahin, Eray, Bartolucci, Martina, Casalini, Sara, Brolatti, Noemi, Pedemonte, Marina, Baratto, Serena, Pintus, Sara, Principi, Elisa, D’Amico, Adele, Pane, Marika, Sframeli, Marina, Messina, Sonia, Albamonte, Emilio, Sansone, Valeria A., Mercuri, Eugenio, Bertini, Enrico, Sezerman, Ugur, Petretto, Andrea, Bruno, Claudio

“…Aim The availability of disease-modifying therapies and newborn screening programs for spinal muscular atrophy (SMA) has generated an urgent need for reliable…”
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Anthropometric and glucometabolic changes in an aged mouse model of lipocalin-2 overexpression by Principi, Elisa, Buschiazzo, Ambra, Papait, Andrea, Castagnola, Patrizio, Costa, Delfina, Pece, Roberta, Maric, Irena, Scussolini, Mara, Marini, Cecilia, Sambuceti, Gianmario, Strollo, Felice, Tavella, Sara

“…Background: Lipocalin-2 (LCN2) is widely expressed in the organism with pleiotropic roles. In particular, its overexpression correlates with tissue stress…”
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Targeting of Ubiquitin E3 Ligase RNF5 as a Novel Therapeutic Strategy in Neuroectodermal Tumors by Principi, Elisa, Sondo, Elvira, Bianchi, Giovanna, Ravera, Silvia, Morini, Martina, Tomati, Valeria, Pastorino, Cristina, Zara, Federico, Bruno, Claudio, Eva, Alessandra, Pedemonte, Nicoletta, Raffaghello, Lizzia

“…RNF5, an endoplasmic reticulum (ER) E3 ubiquitin ligase, participates to the ER-associated protein degradation guaranteeing the protein homeostasis. Depending…”
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Fenretinide (4-HPR) Targets Caspase-9, ERK 1/2 and the Wnt3a/[beta]-Catenin Pathway in Medulloblastoma Cells and Medulloblastoma Cell Spheroids by Bassani, Barbara, Bartolini, Desirèe, Pagani, Arianna, Principi, Elisa, Zollo, Massimo, Noonan, Douglas M, Albini, Adriana, Bruno, Antonino

“…Medulloblastoma (MB), a neuroectodermal tumor arising in the cerebellum, represents the most frequent childhood brain malignancy. Current treatments for MB…”
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Abstract 2328: Targeting angiogenesis: Anti-docking site peptides to Met receptor and nanotechnology by Cantelmo, Anna Rita, Sogno, Ilaria, Noonan, Douglas M., Focaccetti, Chiara, Principi, Elisa, Albini, Adriana

“…The Met tyrosine kinase receptor is involved in different cell responses during development and pathological conditions. In cancer, Met can promote growth,…”
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