Hyperleukocytosis: A Rare Manifestation of Autoimmune Hemolytic Anemia

Autoimmune hemolytic anemia (AIHA) is described by destruction of Red Blood Cells (RBCs) as a result of binding of antibodies to red blood cell surface antigens. White blood cells are usually normal and hyperleukocytosis is rare. The most common microorganism that has been associated with these hemo...

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Bibliographic Details
Published in:	Pakistan Journal of Medicine and Dentistry Vol. 9; no. 4
Main Authors:	Sema Yilmaz, Ilknur Uzunoglu, Nursima Cukadar, Egemen Tavrak, Elif Suleymanoglu
Format:	Journal Article
Language:	English
Published:	ziauddin University 01-05-2024
Subjects:	autoimmune hemolytic anemia, child, leukocytosis, mycoplasma
Online Access:	Get full text
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Summary:	Autoimmune hemolytic anemia (AIHA) is described by destruction of Red Blood Cells (RBCs) as a result of binding of antibodies to red blood cell surface antigens. White blood cells are usually normal and hyperleukocytosis is rare. The most common microorganism that has been associated with these hemolytic processes is Mycoplasma pneumoniae. We presented a case study, a 4-year-old boy child who was diagnosed AIHA by warm antibody testing with high leukocyte count. The patient was treated with methylprednisolone, intravenous immunoglobulin and clarithromycin. During treatment, the leukocytosis became normal. The clinical condition and vital signs improved. The purpose of this study was to highlight hyperleukocytosis in AIHA caused by Mycoplasma pneumoniae. Keywords: Autoimmune Hemolytic Anemia, Child, Leukocyte, Mycoplasma.
ISSN:	2313-7371 2308-2593
DOI:	10.36283/PJMD9-4/016