Search Results - "Elies, Jacobo"
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Degradation and Characterisation of Electrospun Polycaprolactone (PCL) and Poly(lactic-co-glycolic acid) (PLGA) Scaffolds for Vascular Tissue Engineering
Published in Materials (24-08-2021)“…The current study aimed to evaluate the characteristics and the effects of degradation on the structural properties of Poly(lactic-co-glycolic acid) (PLGA)-…”
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Editorial: Trends post-COVID-19 attack: the cardiocerebral system safety remains of utmost concern
Published in Frontiers in physiology (11-07-2023)Get full text
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Fabrication and Characterization of PCL/PLGA Coaxial and Bilayer Fibrous Scaffolds for Tissue Engineering
Published in Materials (22-10-2021)“…Electrospinning is an innovative new fibre technology that aims to design and fabricate membranes suitable for a wide range of tissue engineering (TE)…”
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Co-Loading of Black Phosphorus Nanoflakes and Doxorubicin in Lysolipid Temperature-Sensitive Liposomes for Combination Therapy in Prostate Cancer
Published in International journal of molecular sciences (21-12-2023)“…Black phosphorus (BP) is one of the most promising nanomaterials for cancer therapy. This 2D material is biocompatible and has strong photocatalytic activity,…”
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Downregulation of Vascular Hemeoxygenase-1 Leads to Vasculopathy in Systemic Sclerosis
Published in Frontiers in physiology (05-05-2022)“…Systemic sclerosis (SSc) is a terminal disease characterized by vasculopathy, tissue fibrosis, and autoimmunity. Although the exact etiology of SSc remains…”
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TRPA1–FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p
Published in Nature communications (16-10-2017)“…Recent evidence suggests that the ion channel TRPA1 is implicated in lung adenocarcinoma (LUAD), where its role and mechanism of action remain unknown. We have…”
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Encapsulation and Delivery of Mitoxantrone Using Zirconium-Based Metal–Organic Frameworks (MOFs) and Their Cytotoxic Potential in Breast Cancer Cells
Published in Applied sciences (01-02-2024)“…Mitoxantrone (MTX) is a drug employed in breast cancer treatment, but its application is largely limited due to side effects. A controlled delivery approach…”
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Investigation of Cell Adhesion and Cell Viability of the Endothelial and Fibroblast Cells on Electrospun PCL, PLGA and Coaxial Scaffolds for Production of Tissue Engineered Blood Vessel
Published in Journal of functional biomaterials (01-12-2022)“…Endothelialization of artificial scaffolds is considered an effective strategy for increasing the efficiency of vascular transplantation. This study aimed to…”
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PKA and Epac activation mediates cAMP-induced vasorelaxation by increasing endothelial NO production
Published in Vascular pharmacology (01-03-2014)“…Abstract Vascular relaxation induced by 3′,5′-cyclic adenosine monophosphate (cAMP) is both endothelium-dependent and endothelium-independent, although the…”
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Effects of trans-and cis-resveratrol on Ca2+ handling in A7r5 vascular myocytes
Published in European journal of pharmacology (22-12-2007)“…Although the natural polyphenol resveratrol posses a direct vasorelaxant effect, its effects on cytoplasmic Ca(2+) concentration ([Ca(2+)](i)) in vascular…”
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Trans-resveratrol simultaneously increases cytoplasmic Ca2+ levels and nitric oxide release in human endothelial cells
Published in Molecular nutrition & food research (01-08-2011)“…Scope: The aim of this study was to investigate whether the dietary polyphenol trans‐resveratrol (t‐Resv) increases [Ca2+]c in endothelial cells, leading to a…”
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Cyclic AMP relaxation of rat aortic smooth muscle is mediated in part by decrease of depletion of intracellular Ca2+ stores and inhibition of capacitative calcium entry
Published in Vascular pharmacology (01-01-2013)“…Despite a large number of studies, the mechanism by which 3′,5′-cyclic monophosphate (cAMP) induces vasorelaxation is not fully understood. The comparison…”
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Oligo(styryl)benzenes liposomal AIE-dots for bioimaging and phototherapy in an in vitro model of prostate cancer
Published in Journal of colloid and interface science (15-09-2024)“…[Display omitted] Whilst the development of advanced organic dots with aggregation-induced emission characteristics (AIE-dots) is being intensively studied,…”
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Engineering PSMA-targeted nanoparticles co-encapsulating mitoxantrone and indocyanine green for precise combinatory therapy in prostate cancer
Published in Journal of drug delivery science and technology (01-12-2024)“…Prostate cancer is the 2nd most common cancer in men worldwide. Chemotherapeutic treatment of prostate cancer with mitoxantrone (MTX) has limited efficacy due…”
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Scleroderma fibroblasts suppress angiogenesis via TGF-β/caveolin-1 dependent secretion of pigment epithelium-derived factor
Published in Annals of the rheumatic diseases (01-03-2018)“…Systemic sclerosis (SSc) is characterised by tissue fibrosis and vasculopathy with defective angiogenesis. Transforming growth factor beta (TGF-β) plays a…”
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Regulation of the T‐type Ca2+ channel Cav3.2 by hydrogen sulfide: emerging controversies concerning the role of H2S in nociception
Published in The Journal of physiology (01-08-2016)“…Ion channels represent a large and growing family of target proteins regulated by gasotransmitters such as nitric oxide, carbon monoxide and, as described more…”
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Abstract 4386: Comparison of cytotoxicity of anthracycline based antineoplastic drugs in breast cancer
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Mitoxantrone (MTX) is used for the chemotherapeutic treatment of breast cancer, but it has a dose-limiting cardiotoxicity. One of the mechanisms of…”
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Hydrogen sulfide inhibits Cav3.2 T‐type Ca2+ channels
Published in The FASEB journal (01-12-2014)“…The importance of H2S as a physiological signaling molecule continues to develop, and ion channels are emerging as a major family of target proteins through…”
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Regulation of the T‐type Ca 2+ channel Cav3.2 by hydrogen sulfide: emerging controversies concerning the role of H 2 S in nociception
Published in The Journal of physiology (01-08-2016)“…Abstract Ion channels represent a large and growing family of target proteins regulated by gasotransmitters such as nitric oxide, carbon monoxide and, as…”
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Regulation of the T-type Ca super(2+) channel Cav3.2 by hydrogen sulfide: emerging controversies concerning the role of H sub(2)S in nociception
Published in The Journal of physiology (01-08-2016)“…Ion channels represent a large and growing family of target proteins regulated by gasotransmitters such as nitric oxide, carbon monoxide and, as described more…”
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