Search Results - "Elias, Paul Z."

Pre-malignant conditions diagnosed following a positive cancer signal from a multi-cancer early detection test by Choudhry, Omair A., Kharge, Angana B., Rego, Seema P., Elias, Paul Z., Buchanan, Adam H., Lennon, Anne Marie, Papadopoulos, Nickolas, Diehl, Frank, Beer, Tomasz M.

“…Blood-based tests for multi-cancer early detection (MCED) are being developed to facilitate the detection of various cancer types. The Detecting cancers…”
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Viscoelastic characterization of rat cerebral cortex and type I collagen scaffolds for central nervous system tissue engineering by Elias, Paul Z., Spector, Myron

“…In the field of tissue engineering and regenerative medicine for the central nervous system, therapeutic strategies may involve implantation of biomaterial…”
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Implantation of a collagen scaffold seeded with adult rat hippocampal progenitors in a rat model of penetrating brain injury by Elias, Paul Z., Spector, Myron

“…► We seeded collagen scaffolds with adult rat hippocampal progenitor cells. ► We implanted cell-seeded scaffolds into a rat model of penetrating brain injury…”
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A functionalized, injectable hydrogel for localized drug delivery with tunable thermosensitivity: Synthesis and characterization of physical and toxicological properties by Elias, Paul Z., Liu, Gary W., Wei, Hua, Jensen, Michael C., Horner, Philip J., Pun, Suzie H.

“…Thermosensitive injectable hydrogels have been used for the delivery of pharmacological and cellular therapies in a variety of soft tissue applications. A…”
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Multiyear Clinical Outcomes of Cancers Diagnosed Following Detection by a Blood-Based Multicancer Early Detection Test by Buchanan, Adam H, Lennon, Anne M, Choudhry, Omair A, Elias, Paul Z, Rego, Seema P, Sadler, Jennifer R, Roberta, Julia, Zhang, Yongqiang, Flake, 2nd, Darl D, Salvati, Zachary M, Wagner, Eric S, Fishman, Elliot K, Papadopoulos, Nickolas, Beer, Tomasz M

“…In the US, <20% of cancers are diagnosed by standard-of-care (SoC) screening. Multicancer early detection (MCED) tests offer the opportunity to expand cancer…”
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Treatment of penetrating brain injury in a rat model using collagen scaffolds incorporating soluble Nogo receptor by Elias, Paul Z., Spector, Myron

“…Injuries and diseases of the central nervous system (CNS) have the potential to cause permanent loss of brain parenchyma, with severe neurological…”
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Characterization of a bilateral penetrating brain injury in rats and evaluation of a collagen biomaterial for potential treatment by Elias, Paul Z, Spector, Myron

“…Penetrating brain injury (PBI) encountered in both the military and civilian sectors results in high morbidity and mortality due to the absence of effective…”
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Incremental adaptation to yaw head turns during 30 RPM centrifugation by Elias, Paul Z., Jarchow, Thomas, Young, Laurence R.

“…A 3-day incremental protocol was conducted with the aim of adapting human subjects to make head movements comfortably during 30 RPM centrifugation. With motion…”
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Effect of loading rate on the compressive mechanics of the immature baboon cervical spine by Elias, Paul Z, Nuckley, David J, Ching, Randal P

“…Thirty-four cervical spine segments were harvested from 12 juvenile male baboons and compressed to failure at displacement rates of 5, 50, 500, or 5000 mm/s…”
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Modeling sensory conflict and motion sickness in artificial gravity by Elias, Paul Z., Jarchow, Thomas, Young, Laurence R.

“…It is necessary to characterize the vestibular response associated with head movements for various centrifuge rotation rates if one is to explore short-radius…”
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Long-term clinical outcomes of cancers diagnosed following detection by a blood-based multi-cancer early detection (MCED) test by Buchanan, Adam H, Lennon, Anne Marie, Rego, Seema P, Choudhry, Omair A, Elias, Paul Z, Sadler, Jennifer R, Cohen, Joshua D, Douville, Christopher B, Honushefsky, Ashley M, Klein, Alison, Salvati, Zachary M, Sheridan, Kathleen, Tomasetti, Cristian, Wagner, Eric S, Walter, Carroll N, Fishman, Elliot K., Kinzler, Kenneth W., Vogelstein, Bert, Beer, Tomasz M., Papadopoulos, Nickolas

“…3037 Background: Less than 20% of cancers are diagnosed as a result of standard-of-care (SOC) screening in the US. MCED tests may expand screening to more…”
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Outcomes in participants with a false positive multi-cancer early detection (MCED) test: Results from >4 years follow-up from DETECT-A, the first large, prospective, interventional MCED study by Lennon, Anne Marie, Buchanan, Adam H, Rego, Seema P, Choudhry, Omair A, Elias, Paul Z, Sadler, Jennifer R, Cohen, Joshua D, Douville, Christopher B, Honushefsky, Ashley M, Klein, Alison, Salvati, Zachary M, Sheridan, Kathleen, Tomasetti, Cristian, Wagner, Eric S, Walter, Carroll N, Fishman, Elliot K., Kinzler, Kenneth W., Vogelstein, Bert, Beer, Tomasz M., Papadopoulos, Nickolas

“…3039 Background: Recommended standard of care (SOC) early detection tests are solely available for four cancer types and fewer than 20% of incident cancers in…”
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Treatment of penetrating brain injury in a rat model using collagen scaffolds incorporating soluble Nogo receptor: Treatment of penetrating brain injury using collagen scaffolds and Nogo receptor by Elias, Paul Z., Spector, Myron

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Abstract 2449: Case report: DETECT-A participants with pre-malignant conditions by Choudhry, Omair A., Kharge, Angana, Rego, Seema P., Elias, Paul Z., Buchanan, Adam H., Lennon, Anne Marie, Papadopoulos, Nickolas, Diehl, Frank, Beer, Tomasz M.

“…Abstract Background: Blood based tests for multi-cancer early detection (MCED) are being developed to facilitate the earlier detection of various cancer types…”
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Abstract A064: Lung cancer screening adherence among participants in DETECT-A, the first prospective interventional trial of a multi-cancer early detection (MCED) blood test by Buchanan, Adam H., Lennon, Anne Marie, Elias, Paul Z., Lehman, Amy M., Zhang, Yongqiang, Flake, Darl D., Wagner, Eric S., Rego, Seema P., Choudhry, Omair A., Papadopoulos, Nickolas, Beer, Tomasz M.

“…Abstract Background: Lung cancer is the leading cause of cancer death in the US. Adherence to guideline- recommended low-dose computed tomography screening is…”
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