Search Results - "Elia, J"

Acellular and cellular approaches to improve diabetic wound healing by Cho, Hongkwan, Blatchley, Michael R., Duh, Elia J., Gerecht, Sharon

“…Chronic diabetic wounds represent a huge socioeconomic burden for both affected individuals and the entire healthcare system. Although the number of available…”
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Diabetic retinopathy: current understanding, mechanisms, and treatment strategies by Duh, Elia J, Sun, Jennifer K, Stitt, Alan W

“…Diabetic retinopathy (DR) causes significant visual loss on a global scale. Treatments for the vision-threatening complications of diabetic macular edema (DME)…”
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Diabetic Retinopathy: A Position Statement by the American Diabetes Association by Solomon, Sharon D, Chew, Emily, Duh, Elia J, Sobrin, Lucia, Sun, Jennifer K, VanderBeek, Brian L, Wykoff, Charles C, Gardner, Thomas W

“…Diabetic retinopathy diagnostic assessment and treatment options have improved dramatically since the 2002 American Diabetes Association Position Statement…”
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Seeking clarity on retinal findings in patients with COVID-19 by Duh, Elia J

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ACE2 and TMPRSS2 are expressed on the human ocular surface, suggesting susceptibility to SARS-CoV-2 infection by Zhou, Lingli, Xu, Zhenhua, Castiglione, Gianni M., Soiberman, Uri S., Eberhart, Charles G., Duh, Elia J.

“…Conjunctival signs and symptoms are observed in a subset of patients with COVID-19, and SARS-CoV-2 has been detected in tears, raising concerns regarding the…”
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Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds by Castiglione, Gianni M., Xu, Zhenhua, Zhou, Lingli, Duh, Elia J.

“…Birds (Aves) display high metabolic rates and oxygen consumption relative to mammals, increasing reactive oxygen species (ROS) formation. Although excess ROS…”
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Nrf2 promotes reparative angiogenesis through regulation of NADPH oxidase-2 in oxygen-induced retinopathy by Wei, Yanhong, Gong, Junsong, Xu, Zhenhua, Duh, Elia J.

“…Revascularization of ischemic tissue is a highly desirable outcome in multiple diseases, including cardiovascular diseases and ischemic retinopathies…”
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Engineered human vascularized constructs accelerate diabetic wound healing by Shen, Yu-I, Cho, Hongkwan, Papa, Arianne E, Burke, Jacqueline A, Chan, Xin Yi, Duh, Elia J, Gerecht, Sharon

“…Abstract Stem cell-based therapy is emerging as a promising approach for chronic diabetic wounds, but strategies for optimizing both cellular differentiation…”
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Expression of the SARS-CoV-2 Receptor ACE2 in Human Retina and Diabetes—Implications for Retinopathy by Zhou, Lingli, Xu, Zhenhua, Guerra, James, Rosenberg, Avi Z., Fenaroli, Paride, Eberhart, Charles G., Duh, Elia J.

“…PurposeTo investigate the expression of angiotensin-converting enzyme 2 (ACE2), the receptor for SARS-CoV-2 in human retina. MethodsHuman post-mortem eyes from…”
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Exosomal MicroRNA-15a Transfer from the Pancreas Augments Diabetic Complications by Inducing Oxidative Stress by Kamalden, Tengku Ain, Macgregor-Das, Anne M, Kannan, Sangeetha Marimuthu, Dunkerly-Eyring, Brittany, Khaliddin, Nurliza, Xu, Zhenhua, Fusco, Anthony P, Yazib, Syatirah Abu, Chow, Rhuen Chiou, Duh, Elia J, Halushka, Marc K, Steenbergen, Charles, Das, Samarjit

“…MicroRNAs (miRNAs), one type of noncoding RNA, modulate post-transcriptional gene expression in various pathogenic pathways in type 2 diabetes (T2D)…”
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Nrf2 protects photoreceptor cells from photo-oxidative stress induced by blue light by Chen, Wan-Ju, Wu, Caiying, Xu, Zhenhua, Kuse, Yoshiki, Hara, Hideaki, Duh, Elia J.

“…Oxidative stress plays a key role in age-related macular degeneration and hereditary retinal degenerations. Light damage in rodents has been used extensively…”
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Nrf2 acts cell-autonomously in endothelium to regulate tip cell formation and vascular branching by Wei, Yanhong, Gong, Junsong, Thimmulappa, Rajesh K, Kosmider, Beata, Biswal, Shyam, Duh, Elia J

“…Angiogenesis, in which new blood vessels form via endothelial cell (EC) sprouting from existing vessels, is a critical event in embryonic development and…”
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Anaerobic Digestion for Producing Renewable Energy-The Evolution of This Technology in a New Uncertain Scenario by Sevillano, Cristián Arenas, Pesantes, Alby Aguilar, Peña Carpio, Elizabeth, Martínez, Elia J, Gómez, Xiomar

“…Anaerobic digestion is a well-known technology with wide application in the treatment of high-strength organic wastes. The economic feasibility of this type of…”
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Suppression of inner blood-retinal barrier breakdown and pathogenic Müller glia activation in ischemia retinopathy by myeloid cell depletion by Zhou, Lingli, Xu, Zhenhua, Lu, Haining, Cho, Hongkwan, Xie, Yangyiran, Lee, Grace, Ri, Kaoru, Duh, Elia J

“…Ischemic retinopathies including diabetic retinopathy are major causes of vision loss. Inner blood-retinal barrier (BRB) breakdown with retinal vascular…”
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NRF2 plays a protective role in diabetic retinopathy in mice by Xu, Zhenhua, Wei, Yanhong, Gong, Junsong, Cho, Hongkwan, Park, James K., Sung, Ee-Rah, Huang, Hu, Wu, Lijuan, Eberhart, Charles, Handa, James T., Du, Yunpeng, Kern, Timothy S., Thimmulappa, Rajesh, Barber, Alistair J., Biswal, Shyam, Duh, Elia J.

“…Aims/hypothesis Although much is known about the pathophysiological processes contributing to diabetic retinopathy (DR), the role of protective pathways has…”
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Transcription Factor MEF2C Suppresses Endothelial Cell Inflammation via Regulation of NF-κB and KLF2 by Xu, Zhenhua, Yoshida, Takeshi, Wu, Lijuan, Maiti, Debasish, Cebotaru, Liudmila, Duh, Elia J.

“…Endothelial cells play a major role in the initiation and perpetuation of the inflammatory process in health and disease, including their pivotal role in…”
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Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A by Wei, Yanhong, Gong, Junsong, Xu, Zhenhua, Thimmulappa, Rajesh K., Mitchell, Katherine L., Welsbie, Derek S., Biswal, Shyam, Duh, Elia J.

“…Delayed revascularization of ischemic neural tissue is a major impediment to preservation of function in central nervous system (CNS) diseases including stroke…”
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Modified Thermodilution for Simultaneous Cardiac Output and Recirculation Assessment in Veno-venous Extracorporeal Membrane Oxygenation: a prospective diagnostic accuracy study by Berger, David, Stanger, Elia J, Jenni, Hansjörg, Fried, Philipp D, Bachmann, Kaspar F

“…Thermodilution is unreliable in veno-venous extracorporeal membrane oxygenation (VV-ECMO). Systemic oxygenation depends on recirculation fractions and ratios…”
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Deletion of placental growth factor prevents diabetic retinopathy and is associated with Akt activation and HIF1α-VEGF pathway inhibition by Huang, Hu, He, Jianbo, Johnson, Da'Kuawn, Wei, Yanhong, Liu, Ying, Wang, Shuang, Lutty, Gerard A, Duh, Elia J, Semba, Richard D

“…A new diabetic mouse strain, the Akita.PlGF knockout ((-/-)), was generated to study the role of placental growth factor (PlGF) in the pathogenesis of diabetic…”
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Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4 by Xin, Xiaoban, Rodrigues, Murilo, Umapathi, Mahaa, Kashiwabuchi, Fabiana, Ma, Tao, Babapoor-Farrokhran, Savalan, Wang, Shuang, Hu, Jiadi, Bhutto, Imran, Welsbie, Derek S, Duh, Elia J, Handa, James T, Eberhart, Charles G, Lutty, Gerard, Semenza, Gregg L, Montaner, Silvia, Sodhi, Akrit

“…Vision loss from ischemic retinopathies commonly results from the accumulation of fluid in the inner retina [macular edema (ME)]. Although the precise events…”
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