Search Results - "Elhefnawi, Mahmoud M"

In Silico and In Vivo Evaluation of SARS-CoV-2 Predicted Epitopes-Based Candidate Vaccine by Shehata, Mahmoud M., Mahmoud, Sara H., Tarek, Mohammad, Al-Karmalawy, Ahmed A., Mahmoud, Amal, Mostafa, Ahmed, M. Elhefnawi, Mahmoud, Ali, Mohamed A.

“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, the causative agent of coronavirus disease (COVID-19)) has caused relatively high mortality rates…”
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SIRT1 as a potential key regulator for mediating apoptosis in oropharyngeal cancer using cyclophosphamide and all-trans retinoic acid by Haggagy, Mahitab G., Ahmed, Lamiaa A., Sharaky, Marwa, Elhefnawi, Mahmoud M., Omran, Mervat M.

“…Although cyclophosphamide (CTX) has been used for recurrent or metastatic head and neck cancers, resistance is usually expected. Thus, we conducted this study…”
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Telaprevir is a potential drug for repurposing against SARS-CoV-2: computational and in vitro studies by Mahmoud, Amal, Mostafa, Ahmed, Al-Karmalawy, Ahmed A., Zidan, Ahmad, Abulkhair, Hamada S., Mahmoud, Sara H., Shehata, Mahmoud, Elhefnawi, Mahmoud M., Ali, Mohamed A.

“…Drug repurposing is an important approach to the assignment of already approved drugs for new indications. This technique bypasses some steps in the…”
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Progress, pitfalls, and path forward of drug repurposing for COVID-19 treatment by Taibe, Noha Samir, Kord, Maimona A., Badawy, Mohamed Ahmed, Shytaj, Iart Luca, Elhefnawi, Mahmoud M.

“…On 30 January 2020, the World Health Organization (WHO) declared the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic a public…”
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Down-regulation of circulating microRNA let-7a in Egyptian smokers by Rizk, Sanaa A., Metwally, Fateheya M., Elfiky, Asmaa M., Mahmoud, Asmaa A., Badawi, Nadia A., Sharaf, Nevin E., Elhefnawi, Mahmoud M.

“…Altered miRNAs were associated with cigarette smoking. The study aimed to examine the gene expression level of plasma let-7a among healthy smokers and compared…”
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Synthesis, pharmacological activity evaluation and molecular modeling of new polynuclear heterocyclic compounds containing benzimidazole derivatives by Bassyouni, Fatma A., Saleh, Tamer S., ElHefnawi, Mahmoud M., El-Moez, Sherein I. Abd, El-Senousy, Waled M., Abdel-Rehim, Mohamed E.

“…Novel heterocyclic compounds containing benzimidazole derivatives were synthesized from 2-(1 H benzimidazol-2-yl) acetonitrile ( 1 ) and arylhydrazononitrile…”
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Prediction of prognostic biomarkers for Interferon-based therapy to Hepatitis C Virus patients: a metaanalysis of the NS5A protein in subtypes 1a, 1b, and 3a by ElHefnawi, Mahmoud M, Zada, Suher, El-Azab, Iman A

“…Hepatitis C virus (HCV) is a worldwide health problem with no vaccine and the only approved therapy is Interferon-based plus Ribavarin. Response prediction to…”
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Expression profiling and analysis of some miRNAs in subcutaneous white adipose tissue during development of obesity by Youssef, Elham M, Elfiky, Asmaa M, BanglySoliman, Abu-Shahba, Nourhan, Elhefnawi, Mahmoud M

“…MicroRNAs are emerging as new mediators in the regulation of adipocyte physiology and have been approved to play a role in obesity. Despite several studies…”
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Altered expression of WFS1 and NOTCH2 genes associated with diabetic nephropathy in T2DM patients by Sharaf, Sahar A., Kantoush, Nagwa A., Ayoub, Dina F., Ibrahim, Alshaymaa A., Abdelaal, Amaal A., Aziz, Rokaya Abdel, ElHefnawi, Mahmoud M., Ahmed, Amira N.

“…The increased incidence of type 2 diabetes mellitus (T2DM) and the importance of early identification and management of its complications, especially diabetic…”
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Part I: Synthesis, cancer chemopreventive activity and molecular docking study of novel quinoxaline derivatives by Galal, Shadia A., Abdelsamie, Ahmed S., Tokuda, Harukuni, Suzuki, Nobutaka, Lida, Akira, ElHefnawi, Mahmoud M., Ramadan, Raghda A., Atta, Mona H.E., El Diwani, Hoda I.

“…The reaction of o-phenylene diamine and ethyl oxamate is reinvestigated and led to 3-aminoquinoxalin-2(1H)-one rather than benzimidazole-2-carboxamide as was…”
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MicroRNA-150 down Regulation in Acute Myeloid Leukaemia Patients and Its Prognostic Implication by Abdelhalim, Dalia A, Elgamal, Basma M, ElKafoury, Mona R, Hassan, Naglaa M, Hussein, Marwa M, Elhefnawi, Mahmoud M, Elfiky, Asmaa M, Nabil, Mohamed

“…MicroRNAs (miRNAs) are small, non-coding RNAs that are important for post-transcriptional gene regulation in both healthy and morbid conditions. Numerous…”
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An integrated methodology for mining promiscuous proteins: a case study of an integrative bioinformatics approach for hepatitis C virus non-structural 5A protein by Elhefnawi, Mahmoud M, Youssif, Aliaa A, Ghalwash, Atef Z, Behaidy, Wessam H El

“…A methodology for elucidation of structural, functional, and mechanistic knowledge on promiscuous proteins is proposed that constitutes a workflow of…”
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Prediction of prognostic biomarkers for interferon-based therapy to hepatitis C virus patients: a meta-analysis of the NS5A protein in subtypes 1a, 1b, and 3a by ElHefnawi, Mahmoud M, Zada, Suher, El-Azab, Iman A

“…Hepatitis C virus (HCV) is a worldwide health problem with no vaccine and the only approved therapy is Interferon-based plus Ribavarin. Response prediction to…”
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