Search Results - "Elhassanny, Ahmed E.M."

In vitro and in vivo activities of the carbonic anhydrase inhibitor, dorzolamide, against vancomycin-resistant enterococci by Abutaleb, Nader S, Elhassanny, Ahmed E M, Flaherty, Daniel P, Seleem, Mohamed N

“…Vancomycin-resistant enterococci (VRE) are a serious public health threat and a leading cause of healthcare-associated infections. Bacterial resistance to…”
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Cilostazol protects against acetic acid-induced colitis in rats: Possible role for cAMP/SIRT1 pathway by Elshazly, Shimaa M., Elhassanny, Ahmed E.M., Mahmoud, Nevertyty M.

“…The phosphodiesterase-3 inhibitor, cilostazol has been recently shown to protect against chemically induced colitis in animal models. However, whether cyclic…”
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In vivo efficacy of acetazolamide in a mouse model of Neisseria gonorrhoeae infection by Abutaleb, Nader S., Elhassanny, Ahmed E.M., Seleem, Mohamed N.

“…Gonococcal infections represent an urgent public health threat worldwide due to the increasing incidence of infections that has been accompanied by an increase…”
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Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae by Abutaleb, Nader S., Elhassanny, Ahmed E. M., Nocentini, Alessio, Hewitt, Chad S., Elkashif, Ahmed, Cooper, Bruce R., Supuran, Claudiu T., Seleem, Mohamed N., Flaherty, Daniel P.

“…Neisseria gonorrhoeae is a high-priority pathogen of concern due to the growing prevalence of resistance development against approved antibiotics. Herein, we…”
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Auranofin exerts antibacterial activity against Neisseria gonorrhoeae in a female mouse model of genital tract infection by Elhassanny, Ahmed E M, Abutaleb, Nader S, Seleem, Mohamed N

“…Neisseria gonorrhoeae has been classified by the U.S. Centers for Disease Control and Prevention as an urgent threat due to the rapid development of antibiotic…”
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Impaired mitochondrial function of alveolar macrophages in carbon nanotube-induced chronic pulmonary granulomatous disease by Soliman, Eman, Elhassanny, Ahmed E.M., Malur, Anagha, McPeek, Matthew, Bell, Aaron, Leffler, Nancy, Van Dross, Rukiyah, Jones, Jacob L., Malur, Achut G., Thomassen, Mary Jane

“…•MWCNT induces chronic pulmonary granulomatous inflammation.•MWCNT reduces mitochondrial fatty acid oxidation in alveolar macrophages.•MWCNT induces pulmonary…”
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Substituted salicylic acid analogs offer improved potency against multidrug-resistant Neisseria gonorrhoeae and good selectivity against commensal vaginal bacteria by Almolhim, Hanan, Elhassanny, Ahmed E. M., Abutaleb, Nader S., Abdelsattar, Abdallah S., Seleem, Mohamed N., Carlier, Paul R.

“…Drug-resistant Neisseria gonorrhoeae represents a major threat to public health; without new effective antibiotics, untreatable gonococcal infections loom as a…”
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Myeloid ABCG1 Deficiency Enhances Apoptosis and Initiates Efferocytosis in Bronchoalveolar Lavage Cells of Murine Multi-Walled Carbon Nanotube-Induced Granuloma Model by Soliman, Eman, Bhalla, Sophia, Elhassanny, Ahmed E M, Malur, Anagha, Ogburn, David, Leffler, Nancy, Malur, Achut G, Thomassen, Mary Jane

“…The use of carbon nanotubes has increased in the past few decades. Carbon nanotubes are implicated in the pathogenesis of pulmonary sarcoidosis, a chronic…”
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Heme-Dependent ER Stress Apoptosis: A Mechanism for the Selective Toxicity of the Dihydroartemisinin, NSC735847, in Colorectal Cancer Cells by Elhassanny, Ahmed E. M., Soliman, Eman, Marie, Mona, McGuire, Paul, Gul, Waseem, ElSohly, Mahmoud, Van Dross, Rukiyah

“…Colorectal cancer (CRC) is a leading cause of cancer death in the United States. Artemisinin derivatives, including the dihydroartemisinin (DHA) monomers, are…”
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Structure–Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against Neisseria gonorrhoeae by Hewitt, Chad S, Abutaleb, Nader S, Elhassanny, Ahmed E. M, Nocentini, Alessio, Cao, Xufeng, Amos, Devon P, Youse, Molly S, Holly, Katrina J, Marapaka, Anil Kumar, An, Weiwei, Kaur, Jatinder, Krabill, Aaron D, Elkashif, Ahmed, Elgammal, Yehia, Graboski, Amanda L, Supuran, Claudiu T, Seleem, Mohamed N, Flaherty, Daniel P

“…Neisseria gonorrhoeae is an urgent threat to public health in the United States and around the world. Many of the current classes of antibiotics to treat N…”
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Prostaglandin D 2 -ethanolamide induces skin cancer apoptosis by suppressing the activity of cellular antioxidants by Elhassanny, Ahmed E M, Ladin, Daniel A, Soliman, Eman, Albassam, Hussam, Morris, Andrew, Kobet, Robert, Thayne, Kathleen, Burns, Colin, Danell, Allison S, Van Dross, Rukiyah

“…The combined incidence of melanoma and non-melanoma skin cancer (NMSC) is greater than the incidence of all other malignancies in the US. Previously, we…”
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The ferrous iron transporter FtrABCD is required for the virulence of Brucella abortus 2308 in mice by Elhassanny, Ahmed E. M., Anderson, Eric S., Menscher, Evan A., Roop, R. Martin

“…Summary Iron transport has been linked to the virulence of Brucella strains in both natural and experimental hosts. The genes designated BAB2_0837–0840 in the…”
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Prostaglandin D2-ethanolamide induces skin cancer apoptosis by suppressing the activity of cellular antioxidants by Elhassanny, Ahmed E.M., Ladin, Daniel A., Soliman, Eman, Albassam, Hussam, Morris, Andrew, Kobet, Robert, Thayne, Kathleen, Burns, Colin, Danell, Allison S., Van Dross, Rukiyah

“…•PGD2-EA causes apoptotic cell death in melanoma and non-melanoma skin cancer cells.•PGD2-EA is metabolized to J-series prostaglandin-ethanolamides in skin…”
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Diverse Genetic Regulon of the Virulence-Associated Transcriptional Regulator MucR in Brucella abortus 2308 by Caswell, Clayton C, Elhassanny, Ahmed E M, Planchin, Emilie E, Roux, Christelle M, Weeks-Gorospe, Jenni N, Ficht, Thomas A, Dunman, Paul M, Roop, 2nd, R Martin

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Ultra performance liquid chromatography-tandem mass spectrometeric analysis of ethyl acetate fraction from saudi Lavandula coronopifolia Poir and evaluation of its cytotoxic and antioxidant activities by Abdelaziz, Sahar, Hassan, Wafaa H. B., Elhassanny, Ahmed E. M., Al-Yousef, Hanan M., Elsayed, May A., Adel, Rasha

“…Introduction: The ethyl acetate fraction of the Saudi Lavandula coronopifolia Poir has been previously reported to have hepatoprotective activity against…”
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