Search Results - "Elhajmoussa, Yasmin"
-
1
Spred1 deficit promotes treatment resistance and transformation of chronic phase CML
Published in Leukemia (01-02-2022)“…Spred1 is highly expressed in normal hematopoietic stem cells (HSCs). Lack of Spred1 function has been associated with aberrant hematopoiesis and acute…”
Get full text
Journal Article -
2
Microrna-142 Deficiency Promotes Chronic Myeloid Leukemia (CML) Transformation from Chronic Phase (CP) to Blast Crisis (BC)
Published in Blood (05-11-2020)“…Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm resulting from the BCR-ABL1 fusion gene that encodes a constitutively activated tyrosine kinase…”
Get full text
Journal Article -
3
Spred1 Insufficiency in the Hematopoietic and/or Vascular Compartments of the Bone Marrow (BM) Niche Promotes Aggressive Leukemogenesis in Chronic Myelogenous Leukemia (CML)
Published in Blood (13-11-2019)“…Spred1, a member of the Sprouty family of proteins and a negative regulator of RAS-MAPK signaling, is highly expressed in normal hematopoietic stem cells…”
Get full text
Journal Article -
4
Requirement of GTP binding for TIF‐90‐regulated ribosomal RNA synthesis and oncogenic activities in human colon cancer cells
Published in Journal of cellular physiology (01-10-2020)“…Transcription initiation factor 90 (TIF‐90), an alternatively spliced variant of TIF‐IA, differs by a 90 base pair deletion of exon 6. TIF‐90 has been shown to…”
Get full text
Journal Article