Search Results - "Elhage, R."

Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice by ELHAGE, Rima, JAWIEN, Jacek, RUDLING, Mats, LJUNGGREN, Hans-Gustaf, TAKEDA, Kiyoshi, AKIRA, Shizuo, BAYARD, Francis, HANSSON, Göran K

“…Atherosclerosis is an inflammatory disease in which T helper 1 (Th1) immunity has been proposed to play an important role. Nai;ve CD4+ T cells differentiate…”
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Proatherogenic role of interleukin-18: effects on inflammation and action on vascular cells: AUTHORS' RETROSPECTIVE by Elhage, R., Ljunggren, H.-G., Hansson, G. K.

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C‐Terminal Cleavage of Human Foxp3 at a Proprotein Convertase Motif Abrogates its Suppressive Function by Elhage, R., Cheraï, M., Levacher, B., Darrasse‐Jeze, G., Baillou, C., Zhao, X., Khatib, A.‐M., Piaggio, E., Klatzmann, D.

“…Foxp3 plays a critical role in the development and function of regulatory T cells (Tregs). Differences in translational and post‐translational processing of…”
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Differential effects of interleukin-1 receptor antagonist and tumor necrosis factor binding protein on fatty-streak formation in apolipoprotein E-deficient mice by ELHAGE, R, MARET, A, PIERAGGI, M.-T, THIERS, J. C, ARNAL, J. F, BAYARD, F

“…The cytokines interleukin 1 (IL-1) and tumor necrosis factor (TNF) are secreted by the different cell populations of the vascular wall and have been suggested…”
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Involvement of interleukin-6 in atherosclerosis but not in the prevention of fatty streak formation by 17β-estradiol in apolipoprotein E-deficient mice by Elhage, R., Clamens, S., Besnard, S., Mallat, Z., Tedgui, A., Arnal, J.-F., Maret, A., Bayard, F.

“…Interleukin-6 (IL-6) gene expressed in bone marrow-derived stromal cells and osteoblasts contributes to the state of mineralization and its control by…”
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17β-estradiol prevents fatty streak formation in apolipoprotein E-deficient mice by ELHAGE, R, ARNAL, J.-F, PIERAGGI, M.-T, DUVERGER, N, FIEVET, C, FAYE, J.-C, BAYARD, F

“…Abstract The reality of the atheroprotective effect of estrogens is still a matter of debate, and its unknown mechanisms could involve favorable changes in…”
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Estrogens and atherosclerosis by ARNAL, J-F, GOURDY, P, PRATS, A-C, BAYARD, F, ELHAGE, R, GARMY-SUSINI, B, DELMAS, E, BROUCHET, L, CASTANO, C, BARREIRA, Y, COULOUMIERS, J. C, PRATS, H

“…Numerous epidemiological as well as experimental studies have suggested that estradiol (E2) prevents atherosclerosis development. However two controlled…”
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Prevention of fatty streak formation of 17β-estradiol is not mediated by the production of nitric oxide in apolipoprotein E-deficient mice by ELHAGE, R, BAYARD, F, RICHARD, V, HOLVOET, P, DUVERGER, N, FIEVET, C, ARNAL, J.-F

“…Background Estrogens have atheroprotective properties, the mechanisms of which remain obscure. Estrogens have recently been reported to increase endothelial NO…”
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Anti-Inflammatory and Antiatherogenic Effects of the NLRP3 Inflammasome Inhibitor Arglabin in ApoE2.Ki Mice Fed a High-Fat Diet by Abderrazak, Amna, Couchie, Dominique, Mahmood, Dler Faieeq Darweesh, Elhage, Rima, Vindis, Cécile, Laffargue, Muriel, Matéo, Véronique, Büchele, Berthold, Ayala, Monica Rubio, El Gaafary, Menna, Syrovets, Tatiana, Slimane, Mohamed-Naceur, Friguet, Bertrand, Fulop, Tamas, Simmet, Thomas, El Hadri, Khadija, Rouis, Mustapha

“…BACKGROUND—This study was designed to evaluate the effect of arglabin on the NLRP3 inflammasome inhibition and atherosclerotic lesion in ApoE2Ki mice fed a…”
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Estrogens modulate bovine vascular endothelial cell permeability and HSP 25 expression concomitantly by Delarue, F, Daunes, S, Elhage, R, Garcia, A, Bayard, F, Faye, J

“…The atheroprotective properties of estrogens are supported by clinical data from postmenopausal women who use estrogen replacement therapy. However, the…”
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Transfer of CD4+ T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice by XINGHUA ZHOU, NICOLETTI, Antonino, ELHAGE, Rima, HANSSON, Göran K

“…Atherosclerosis is associated with immune responses to oxidized lipoproteins and certain microorganisms, but the role of specific immunity has remained…”
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CD1d-dependent activation of NKT cells aggravates atherosclerosis by Tupin, Emmanuel, Nicoletti, Antonino, Elhage, Rima, Rudling, Mats, Ljunggren, Hans-Gustaf, Hansson, Göran K, Berne, Gabrielle Paulsson

“…Adaptive and innate immunity have been implicated in the pathogenesis of atherosclerosis. Given their abundance in the lesion, lipids might be targets of the…”
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Proatherogenic role of interleukin-18: effects on inflammation and action on vascular cells by Elhage, R, Ljunggren, HG, Hansson, GK

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Deleting TCR alpha beta+ or CD4+ T lymphocytes leads to opposite effects on site-specific atherosclerosis in female apolipoprotein E-deficient mice by Elhage, Rima, Gourdy, Pierre, Brouchet, Laurent, Jawien, Jacek, Fouque, Marie-José, Fiévet, Catherine, Huc, Xavier, Barreira, Yara, Couloumiers, Jean Claude, Arnal, Jean-François, Bayard, Francis

“…Recent studies have demonstrated the importance of lymphocytes, especially CD4(+) T cells, in early lesions of atherosclerosis in hypercholesterolemic mice…”
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17 beta-estradiol prevents fatty streak formation in apolipoprotein E-deficient mice by Elhage, R, Arnal, J F, Pieraggi, M T, Duverger, N, Fiévet, C, Faye, J C, Bayard, F

“…The reality of the atheroprotective effect of estrogens is still a matter of debate, and its unknown mechanisms could involve favorable changes in blood lipids…”
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The Atheroprotective Effect of 17β-Estradiol Depends on Complex Interactions in Adaptive Immunity by Elhage, Rima, Gourdy, Pierre, Jawien, Jacek, Brouchet, Laurent, Castano, Caroine, Fievet, Catherine, Hansson, Göran K., Arnal, Jean-François, Bayard, Francis

“…Estradiol prevents fatty streak formation in chow-fed atherosclerosis-prone apolipoprotein E (ApoE)-deficient mice. We previously reported that fatty streak…”
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Estrogens and atherosclerosis by Bayard, F, Gourdy, P, Elhage, R, Brouchet, L, Garmy-Susini, B, Castano, C, Barreira, Y, Couloumiers, J C, Arnal, J F

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Loss of atheroprotective effect of estradiol in immunodeficient mice by Elhage, R, Clamens, S, Reardon-Alulis, C, Getz, G S, Fievet, C, Maret, A, Arnal, J F, Bayard, F

“…Estradiol significantly decreases fatty streak formation in the aortic root of chow-fed apolipoprotein E-deficient mice. In contrast, immunodeficient mice with…”
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Transfer of CD4+ T cells aggravates atherosclerosis in immunodeficient apoE−/− mice by Zhou, X., Nicoletti, A., Elhage, R., Hansson, G.K.

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The atheroprotective effect of 17beta-estradiol depends on complex interactions in adaptive immunity by Elhage, Rima, Gourdy, Pierre, Jawien, Jacek, Brouchet, Laurent, Castano, Caroine, Fievet, Catherine, Hansson, Göran K, Arnal, Jean-François, Bayard, Francis

“…Estradiol prevents fatty streak formation in chow-fed atherosclerosis-prone apolipoprotein E (ApoE)-deficient mice. We previously reported that fatty streak…”
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