Search Results - "Elhady, Sameh S"

Molecular Docking and Dynamics Simulation Revealed the Potential Inhibitory Activity of ACEIs Against SARS-CoV-2 Targeting the hACE2 Receptor by Al-Karmalawy, Ahmed A., Dahab, Mohammed A., Metwaly, Ahmed M., Elhady, Sameh S., Elkaeed, Eslam B., Eissa, Ibrahim H., Darwish, Khaled M.

“…The rapid and global spread of a new human coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has produced an immediate urgency to…”
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Calendulaglycoside A showing potential activity against SARS-CoV-2 main protease: Molecular docking, molecular dynamics, and SAR studies by Zaki, Ahmed A., Ashour, Ahmed, Elhady, Sameh S., Darwish, Khaled M., Al-Karmalawy, Ahmed A.

“…Background and aim: The discovery of drugs capable of inhibiting SARS-CoV-2 is a priority for human beings due to the severity of the global health pandemic…”
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Valorization of Pimenta racemosa Essential Oils and Extracts: GC-MS and LC-MS Phytochemical Profiling and Evaluation of Helicobacter pylori Inhibitory Activity by Ayoub, Iriny M, Abdel-Aziz, Marwa M, Elhady, Sameh S, Bagalagel, Alaa A, Malatani, Rania T, Elkady, Wafaa M

“…is a commonly known spice used in traditional medicine to treat several ailments. In this study, comprehensive phytochemical profiling of the essential oils…”
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Computational and Biological Evaluation of β -Adrenoreceptor Blockers as Promising Bacterial Anti-Virulence Agents by Almalki, Ahmad J, Ibrahim, Tarek S, Elhady, Sameh S, Hegazy, Wael A H, Darwish, Khaled M

“…Bacterial resistance to antibiotics is an increasing public health threat as it has the potential to affect people at any stage of life, as well as veterinary…”
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In Silico and In Vitro Studies for Benzimidazole Anthelmintics Repurposing as VEGFR-2 Antagonists: Novel Mebendazole-Loaded Mixed Micelles with Enhanced Dissolution and Anticancer Activity by Elmaaty, Ayman Abo, Darwish, Khaled M, Chrouda, Amani, Boseila, Amira A, Tantawy, Mohamed A, Elhady, Sameh S, Shaik, Afzal B, Mustafa, Muhamad, Al-Karmalawy, Ahmed A

“…Cancer is a leading cause of death worldwide and its incidence is unfortunately anticipated to rise in the next years. On the other hand, vascular endothelial…”
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Anti- Cryptosporidium parvum activity of Artemisia judaica L. and its fractions: in vitro and in vivo assays by Ahmed, Shahira A, Eltamany, Enas E, Nafie, Mohamed S, Elhady, Sameh S, Karanis, Panagiotis, Mokhtar, Amira B

“…This study investigates the toxic activity of ethanolic extract (ArEx) as well as its phenolic fraction (ArPh), and terpenoid fraction (ArT) against ( )…”
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Neuroprotective Effects of Black Pepper Cold-Pressed Oil on Scopolamine-Induced Oxidative Stress and Memory Impairment in Rats by Mostafa, Nada M, Mostafa, Ahmed M, Ashour, Mohamed L, Elhady, Sameh S

“…Oxidative stress is usually associated with many neurodegenerative diseases. In this study, the gas chromatography-mass spectrometry (GC-MS) analysis of…”
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Evaluation of The Antioxidant, Antimicrobial, and Anticancer Activities of Dicliptera bupleuroides Isolated Compounds Using In Vitro and In Silico Studies by Akbar, Shehla, Ishtiaq, Saiqa, Jahangir, Muhammad, Elhady, Sameh S, Bogari, Hanin A, Alahdal, Abdelrahman M, Ashour, Mohamed L, Youssef, Fadia S

“…Phytochemical investigation of chloroform fraction (DBC) and ethyl acetate fraction (DBE) of (Acanthaceae) resulted in the isolation of β-sitosterol ( ) from…”
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Design and Synthesis of Coumarin Derivatives as Cytotoxic Agents through PI3K/AKT Signaling Pathway Inhibition in HL60 and HepG2 Cancer Cells by Kishk, Safaa M, Eltamany, Enas E, Nafie, Mohamed S, Khinkar, Roaa M, Hareeri, Rawan H, Elhady, Sameh S, Yassen, Asmaa S. A

“…In this study, a series of coumarin derivatives, either alone or as hybrids with cinnamic acid, were synthesized and evaluated for their cytotoxicity against a…”
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LC-MS based metabolic profiling and wound healing activity of a chitosan nanoparticle-loaded formula of Teucrium polium in diabetic rats by Algandaby, Mardi M., Esmat, Ahmed, Nasrullah, Mohammed Z., Alhakamy, Nabil A., Abdel-Naim, Ashraf B., Rashad, Omar M., Elhady, Sameh S., Eltamany, Enas E.

“…Healing of wounds is the most deteriorating diabetic experience. Felty germander (Teucrium polium) possesses antioxidant, anti-inflammatory and antimicrobial…”
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Exploring the Synergistic Effect of Bergamot Essential Oil with Spironolactone Loaded Nano-Phytosomes for Treatment of Acne Vulgaris: In Vitro Optimization, In Silico Studies, and Clinical Evaluation by Albash, Rofida, Badawi, Noha M, Hamed, Mohammed I A, Ragaie, Maha H, Mohammed, Sahar S, Elbesh, Rovan M, Darwish, Khaled M, Lashkar, Manar O, Elhady, Sameh S, Mosallam, Shaimaa

“…The foremost target of the current work was to formulate and optimize a novel bergamot essential oil (BEO) loaded nano-phytosomes (NPs) and then combine it…”
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Antimicrobial Chlorinated 3-Phenylpropanoic Acid Derivatives from the Red Sea Marine Actinomycete Streptomyces coelicolor LY001 by Shaala, Lamiaa A, Youssef, Diaa T A, Alzughaibi, Torki A, Elhady, Sameh S

“…The actinomycete strain LY001 was purified from the sponge . Fractionation of the antimicrobial extract of the culture of the actinomycete afforded three new…”
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FTIR Characterization of Sulfated Polysaccharides Obtained from Macrocystis integrifolia Algae and Verification of Their Antiangiogenic and Immunomodulatory Potency In Vitro and In Vivo by Soto-Vásquez, Marilú Roxana, Alvarado-García, Paúl Alan Arkin, Youssef, Fadia S, Ashour, Mohamed L, Bogari, Hanin A, Elhady, Sameh S

“…The aim of this study was to evaluate the antiangiogenic and immunomodulatory potential of sulfated polysaccharides from the marine algae Macrocystis…”
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Evaluation of 2-Thioxoimadazolidin-4-one Derivatives as Potent Anti-Cancer Agents through Apoptosis Induction and Antioxidant Activation: In Vitro and In Vivo Approaches by Nafie, Mohamed S, Khodair, Ahmed I, Hassan, Hebat Allah Y, El-Fadeal, Noha M Abd, Bogari, Hanin A, Elhady, Sameh S, Ahmed, Safwat A

“…Hepatocellular carcinoma (HCC) is one of the most widespread malignancies and is reported as the fourth most prevalent cause of cancer deaths worldwide…”
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Silviridoside: A New Triterpene Glycoside from Silene viridiflora with Promising Antioxidant and Enzyme Inhibitory Potential by Makhmudova, Markhabo M, Bacher, Markus, Zengin, Gokhan, Rosenau, Thomas, Youssef, Fadia S, Almasri, Diena M, Elhady, Sameh S, Mamadalieva, Nilufar Z

“…A new triterpene glycoside, silviridoside, was isolated from the aerial parts of (Caryophyllaceae) using different chromatographic techniques. The structure of…”
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Chemomodulatory Effect of the Marine-Derived Metabolite "Terrein" on the Anticancer Properties of Gemcitabine in Colorectal Cancer Cells by Abuhijjleh, Reham Khaled, Al Saeedy, Dalia Yousef, Ashmawy, Naglaa S, Gouda, Ahmed E, Elhady, Sameh S, Al-Abd, Ahmed Mohamed

“…Terrein (Terr) is a bioactive marine secondary metabolite that possesses antiproliferative/cytotoxic properties by interrupting various molecular pathways…”
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Molecular Docking and Dynamics Simulation Study of Hyrtios erectus Isolated Scalarane Sesterterpenes as Potential SARS-CoV-2 Dual Target Inhibitors by Elhady, Sameh S., Abdelhameed, Reda F. A., Malatani, Rania T., Alahdal, Abdulrahman M., Bogari, Hanin A., Almalki, Ahmad J., Mohammad, Khadijah A., Ahmed, Safwat A., Khedr, Amgad I. M., Darwish, Khaled M.

“…Presently, the world is under the toll of pandemic coronavirus disease-2019 (COVID-19) outbreak caused by SARS-CoV-2. Lack of effective and safe therapeutics…”
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In Vitro Anti-Inflammatory Activity of Cotula anthemoides Essential Oil and In Silico Molecular Docking of Its Bioactives by Refaey, Mohamed, Abouelela, Mohamed, El-Shoura, Ehab, Alkhalidi, Hala, Fadil, Sana, Elhady, Sameh, Abdelhameed, Reda

“…The genus Cotula (Asteraceae) comprises about 80 species, amongst them Cotula anthemoides L. It is a wild plant growing in Egypt that possesses many…”
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Ziziphus spina-christi L. extract attenuates bleomycin-induced lung fibrosis in mice via regulating TGF-β1/SMAD pathway: LC-MS/MS Metabolic profiling, chemical composition, and histology studies by Elhady, Sameh S., Goda, Marwa S., Mehanna, Eman T., El-Sayed, Norhan M., Hazem, Reem M., Elfaky, Mahmoud A., Almalki, Ahmad J., Mohamed, Malik Suliman, Abdelhameed, Reda F.A.

“…Ancient Egyptians (including Bedouins and Nubians) have long utilized Ziziphus spina-christi (L.), a traditional Arabian medicinal herb, to alleviate swellings…”
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HBD-2 variants and SARS-CoV-2: New insights into inter-individual susceptibility by Behairy, Mohammed Y, Soltan, Mohamed A, Eldeen, Muhammad Alaa, Abdulhakim, Jawaher A, Alnoman, Maryam M, Abdel-Daim, Mohamed M, Otifi, Hassan, Al-Qahtani, Saleh M, Zaki, Mohamed Samir A, Alsharif, Ghadi, Albogami, Sarah, Jafri, Ibrahim, Fayad, Eman, Darwish, Khaled M, Elhady, Sameh S, Eid, Refaat A

“…A deep understanding of the causes of liability to SARS-CoV-2 is essential to develop new diagnostic tests and therapeutics against this serious virus in order…”
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