Search Results - "Elgoyhen, Ana B"

Commentary: Nicotinic Acetylcholine Receptor α9 and α10 Subunits Are Expressed in the Brain of Mice by Morley, Barbara J, Whiteaker, Paul, Elgoyhen, Ana B

“…[...]if correct, their results could result in re-interpretation of a large number of solid and reproducible published studies. [...]they found no α9 protein…”
Get full text

Engineering olivocochlear inhibition to reduce acoustic trauma by Zhang, Yuanyuan, Hiel, Hakim, Vincent, Philippe F.Y., Wood, Megan B., Elgoyhen, Ana B., Chien, Wade, Lauer, Amanda, Fuchs, Paul A.

“…Efferent brain-stem neurons release acetylcholine to desensitize cochlear hair cells and can protect the inner ear from acoustic trauma. That protection is…”
Get full text

Tinnitus: network pathophysiology-network pharmacology by Elgoyhen, Ana B, Langguth, Berthold, Vanneste, Sven, De Ridder, Dirk

“…Tinnitus, the phantom perception of sound, is a prevalent disorder. One in 10 adults has clinically significant subjective tinnitus, and for one in 100,…”
Get full text

Novel Pathogenic Variants in the Gene Encoding Stereocilin ( STRC ) Causing Non-Syndromic Moderate Hearing Loss in Spanish and Argentinean Subjects by Domínguez-Ruiz, María, Ruiz-Palmero, Laura, Buonfiglio, Paula I, García-Vaquero, Irene, Gómez-Rosas, Elena, Goñi, Marina, Villamar, Manuela, Morín, Matías, Moreno-Pelayo, Miguel A, Elgoyhen, Ana B, Del Castillo, Francisco J, Dalamón, Viviana, Del Castillo, Ignacio

“…Non-syndromic hearing impairment (NSHI) is a very heterogeneous genetic condition, involving over 130 genes. Mutations in , encoding connexin-26, are a major…”
Get full text

Key role of the TM2-TM3 loop in calcium potentiation of the α9α10 nicotinic acetylcholine receptor by Gallino, Sofia L., Agüero, Lucía, Boffi, Juan C., Schottlender, Gustavo, Buonfiglio, Paula, Dalamon, Viviana, Marcovich, Irina, Carpaneto, Agustín, Craig, Patricio O., Plazas, Paola V., Elgoyhen, Ana B.

“…The α9α10 nicotinic cholinergic receptor (nAChR) is a ligand-gated pentameric cation-permeable ion channel that mediates synaptic transmission between…”
Get full text

Pharmacological approaches to the treatment of tinnitus by Elgoyhen, Ana B., Langguth, Berthold

“…Tinnitus is the conscious perception of a phantom sound in the absence of an external source. For 1 in 100 of the general population, the condition severely…”
Get full text

The Remarkable Outer Hair Cell: Proceedings of a Symposium in Honour of W. E. Brownell by Ashmore, Jonathan F., Oghalai, John S., Dewey, James B., Olson, Elizabeth S., Strimbu, Clark E., Wang, Yi, Shera, Christopher A., Altoè, Alessandro, Abdala, Carolina, Elgoyhen, Ana B., Eatock, Ruth Anne, Raphael, Robert M.

“…In 1985, Bill Brownell and colleagues published the remarkable observation that cochlear outer hair cells (OHCs) express voltage-driven mechanical motion:…”
Get full text

Editorial: Auditory Efferent System: New Insights from Cortex to Cochlea by Delano, Paul H, Elgoyhen, Ana B

Get full text

Gap-junctional channel and hemichannel activity of two recently identified connexin 26 mutants associated with deafness by Dalamon, Viviana, Fiori, Mariana C., Figueroa, Vania A., Oliva, Carolina A., del Rio, Rodrigo, Gonzalez, Wendy, Canan, Jonathan, Elgoyhen, Ana B., Altenberg, Guillermo A., Retamal, Mauricio A.

“…Gap-junction channels (GJCs) are formed by head-to-head association of two hemichannels (HCs, connexin hexamers). HCs and GJCs are permeable to ions and…”
Get full text

Inhibition of the α9α10 nicotinic cholinergic receptor by neramexane, an open channel blocker of N-methyl- d-aspartate receptors by Plazas, Paola V., Savino, Jessica, Kracun, Sebastian, Gomez-Casati, María E., Katz, Eleonora, Parsons, Christopher G., Millar, Neil S., Elgoyhen, Ana B.

“…In this study we report the effects of neramexane, a novel amino-alkyl-cyclohexane derivative that is a non-competitive N-methyl- d-aspartate (NMDA) receptor…”
Get full text

Identification of the subunits of the nicotinic cholinergic receptors in the rat cochlea using RT–PCR and in situ hybridization by Morley, Barbara J, Li, Ha-Sheng, Hiel, Hakim, Drescher, Dennis G, Elgoyhen, Ana B

“…There are two tissues in the adult mammalian cochlea that are post-synaptic to cholinergic efferent fibers: The outer hair cells (OHCs) and the dendrites of…”
Get full text

Auditory efferent system: new insights from cortex to cochlea by Paul Hinckley Delano, Ana B Elgoyhen

Get full text

Inhibition of the alpha9alpha10 nicotinic cholinergic receptor by neramexane, an open channel blocker of N-methyl-D-aspartate receptors by Plazas, Paola V, Savino, Jessica, Kracun, Sebastian, Gomez-Casati, María E, Katz, Eleonora, Parsons, Christopher G, Millar, Neil S, Elgoyhen, Ana B

“…In this study we report the effects of neramexane, a novel amino-alkyl-cyclohexane derivative that is a non-competitive N-methyl-D-aspartate (NMDA) receptor…”
Get full text

Expression of nicotinic acetylcholine receptor mRNA in the adult rat peripheral vestibular system by Hiel, Hakim, Elgoyhen, Ana B., Drescher, Dennis G., Morley, Barbara J.

“…The mRNA expression of the neuronal nicotinic acetylcholine receptor subunits was determined in adult rat vestibular end-organs and in Scarpa's ganglion (SCG)…”
Get full text