Search Results - "Elgazwi, Sara M."
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Novel EGFR‐MAPK kinase and ABC transporter inhibitors for HepG2 resistant to Erlotinib
Published in Drug development research (01-04-2023)“…Hepatocellular carcinoma (HCC) is the third‐leading cause of cancer death in the world, with outlook for most patients having a 5‐year survivability of less…”
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Cucurbitacins inspired organic synthesis: Potential dual inhibitors targeting EGFR – MAPK pathway
Published in European journal of medicinal chemistry (01-07-2019)“…Natural products have been known as a fundamental source for drug discovery leading to the evolution of Biological Oriented Organic Synthesis (BIOS) approach…”
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Novel series of 6-(2-substitutedacetamido)-4-anilinoquinazolines as EGFR-ERK signal transduction inhibitors in MCF-7 breast cancer cells
Published in European journal of medicinal chemistry (15-07-2018)“…Epidermal growth factor receptor (EGFR) signaling pathway has been previously investigated for its significant role in the progression of different types of…”
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Design and synthesis of pyrazolo[3,4-d]pyrimidines: Nitric oxide releasing compounds targeting hepatocellular carcinoma
Published in Bioorganic & medicinal chemistry (15-06-2017)“…[Display omitted] A new series of pyrazolo[3,4-d]pyrimidines tethered with nitric oxide (NO) producing functionality was designed and synthesized…”
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