Search Results - "Elfick, P."

ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy by Nixon, Mark, Mackenzie, Scott D, Taylor, Ashley I, Homer, Natalie Z M, Livingstone, Dawn E, Mouras, Rabah, Morgan, Ruth A, Mole, Damian J, Stimson, Roland H, Reynolds, Rebecca M, Elfick, Alistair P D, Andrew, Ruth, Walker, Brian R

“…The aim of treatment in congenital adrenal hyperplasia is to suppress excess adrenal androgens while achieving physiological glucocorticoid replacement…”
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Development of tip-enhanced optical spectroscopy for biological applications: a review by Elfick, Alistair P. D, Downes, Andrew R, Mouras, Rabah

“…Tip-enhanced optical spectroscopy is an approach that holds a good deal of promise for the nanoscale characterisation of matter. Tip-enhanced Raman…”
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Label-free assessment of adipose-derived stem cell differentiation using coherent anti-Stokes Raman scattering and multiphoton microscopy by Mouras, Rabah, Bagnaninchi, Pierre O., Downes, Andrew R., Elfick, Alistair P. D.

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The nature and dissemination of UHMWPE wear debris retrieved from periprosthetic tissue of THR by Elfick, Alistair P. D., Green, Sarah M., Krikler, Steve, Unsworth, Anthony

“…The role of wear debris in provoking joint replacement failure through bone resorption is now supported by much research. This study presents the analysis of…”
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Non-invasive methods of monitoring Fe3O4 magnetic nanoparticle toxicity in human liver HepaRG cells using impedance biosensing and Coherent anti-Stokes Raman spectroscopic (CARS) microscopy by Kuhn, Joel, McDonald, Alison, Mongoin, Cyril, Anderson, Graham, Lafeuillade, Guillemette, Mitchell, Stephen, Elfick, Alistair P.D., Bagnaninchi, Pierre O., Yiu, Humphrey H.P., Nelson, Leonard J.

“…Functionalized nanoparticles have been developed for use in nanomedicines for treating life threatening diseases including various cancers. To ensure safe use…”
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Fabrication and evaluation of poly(lactic acid), chitosan, and tricalcium phosphate biocomposites for guided bone regeneration by Ramesh, Srikanthan, Lungaro, Lisa, Tsikritsis, Dimitrios, Weflen, Eric, Rivero, Iris V., Elfick, Alistair P. D.

“…ABSTRACT This study presents and evaluates an approach for fabricating poly(lactic acid) (PLA)/chitosan (CS)/tricalcium phosphate (TCP) electrospun scaffolds…”
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Label-free assessment of adipose-derived stem cell differentiation using coherent anti-Stokes Raman scattering and multiphoton microscopy by Mouras, Rabah, Bagnaninchi, Pierre O, Downes, Andrew R, Elfick, Alistair P D

“…Adult stem cells (SCs) hold great potential as likely candidates for disease therapy but also as sources of differentiated human cells in vitro models of…”
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The effect of 'running-in' on the tribology and surface morphology of metal-on-metal Birmingham hip resurfacing device in simulator studies by Vassiliou, K, Elfick, A P D, Scholes, S C, Unsworth, A

“…It is well documented that hard bearing combinations show a running-in phenomenon in vitro and there is also some evidence of this from retrieval studies. In…”
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An evaluation of the tribological performance of zirconia and CoCrMo femoral heads by SMITH, S. L, ELFICK, A. P. D, UNSWORTH, A

“…Five new zirconia, five new CoCrMo and three explanted CoCrMo femoral heads were wear-tested in bovine serum for five million cycles using the Durham Hip Joint…”
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A novel technique for the detailed size characterization of wear debris by Elfick, A P, Green, S M, Pinder, I M, Unsworth, A

“…The accurate and detailed characterization of artificial joint wear debris is important in determining both the wear rate of prostheses and understanding the…”
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Cryomilled zinc sulfide: A prophylactic for Staphylococcus aureus-infected wounds by Tran, Phat L, Li, Jianqiang, Lungaro, Lisa, Ramesh, Srikanthan, Ivanov, Ilia N, Moon, Ji-Won, Graham, David E, Hamood, Abdul, Wang, James, Elfick, Alistair PD, Rivero, Iris V

“…Bacterial pathogens that colonize wounds form biofilms, which protect the bacteria from the effect of host immune response and antibiotics. This study examined…”
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The effect of socket design, materials and liner thickness on the wear of the porous coated anatomic total hip replacement by Elfick, A P, Hall, R M, Pinder, I M, Unsworth, A

“…The wear of joint replacement prostheses represents the greatest challenge to their continued development. Parameters such as polyethylene quality, liner…”
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The frictional behaviour of explanted PCA hip prostheses by Elfick, A P, Hall, R M, Pinder, I M, Unsworth, A

“…The frictional characteristic of 22 explanted and two unused PCA total hip arthoplasties were assessed using the Durham hip simulator. The friction of the…”
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An Intel 3 Advanced FinFET Platform Technology for High Performance Computing and SOC Product Applications by Hafez, W., Abdelkader, M., An, S., Auth, C., Bahr, D., Bambery, R., Beck, M., Bhowmick, S., Biggs-houck, J., Caselli, D., Chang, H.-Y., Chang, Y., Chauhan, S., Chikkadi, K., Chu, T., Connor, C., Diana, D., Dong, Y., Elfick, P., Elko-hansen, T., Gala, D., Geppert, C., Govindaraju, S., Grimm, W., Grunes, H., Guler, L., Guo, Z., Gupta, A., Havelia, S., Hazra, J., Islam, A., Jain, A., Jamil, M., Jang, M., Kabir, M., Kameswaran, J., Karl, E., Kelgeri, S., Kennedy, A., Kim, J., Kim, Y., Krishnan, D., Lee, G., Lee, H.-P., Lin, H., Luk, A., Luo, Y., Macfarlane, P., Mamun, A., Marla, K., Mckenna, E., Miah, A., Mistry, K., Mleczko, M., Moon, S., Nardi, D., Natarajan, S., Nolph, C., Nugroho, C., Nyhus, P., Oni, A., Packan, P., Paliwal, A., Pandey, R., Paredes, I., Park, K., Paulson, L., Pierre, A., Plekhanov, P., Prasad, C., Ramaswamy, R., Rode, J., Russell, R., Ryu, S., Saavedra, H., Salisbury, T., Sandford, J., Shah, F., Shang, K., Shekhar, P., Shu, A., Skoug, E., Sohn, J., Song, J., Sprinkle, M., Su, J., Tsao, R., Vaidya, A., Wallace, C., Wang, X., Wang, H., Ward, C., Wickramaratne, S., Wills, M., Wu, T., Xia-hua, Z., Xu, S., Yaung, J., Yu, Y., Zilm, M.

“…An advanced Intel 3 FinFET technology is presented that has been optimized to provide 10% logic scaling, a full node of performance improvement and improved…”
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The quantitative assessment of UHMWPE wear debris produced in hip simulator testing: the influence of head material and roughness, motion and loading by Elfick, Alistair P.D, Smith, Simon L, Green, Sarah M, Unsworth, Anthony

“…Biomaterial wear particles are known to provoke a foreign-body reaction when released from total joint prostheses. Considerable effort is being invested in the…”
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Surface topography of retrieved PCA acetabular liners: proposal of a novel wear mechanism by ELFICK, A. P, HALL, R. M, UNSWORTH, A, PINDER, I. M

“…The surface topography of the acetabular linear is evaluated using differential interference contrast microscopy and scanning electron microscopy. The porous…”
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Design and validation of a surrogate humerus for biomechanical testing by Elfick, A.P., Bedi, G., Port, A., Unsworth, A.

“…At present biomechanical testing of fracture plating strategies is conducted using animal or cadaveric whole bone models. This may introduce experimental error…”
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Growth of Native Cadmium Sulfide Films on CdxHg1-xTe from Aqueous Sulfide Solutions by Elfick, P. V, Berlouis, L. E. A, MacDonald, S. M, Affrossman, S, Rocabois, P, Tarry, H

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The influence of femoral head surface roughness on the wear of ultrahigh molecular weight polyethylene sockets in cementless total hip replacement by Elfick, Alistair P. D., Hall, Richard M., Pinder, Ian M., Unsworth, Anthony

“…A theoretical relationship was recently proposed relating the wear behavior of polymetric bearing materials articulating against hard counterfaces.1 This model…”
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A re-appraisal of wear features of acetabular sockets using atomic force microscopy by Elfick, Alistair P.D, Smith, Simon L, Green, Sarah M, Unsworth, Anthony

“…The morphological and material features of 10 worn ultra-high molecular weight polyethylene (UHMWPE) acetabular sockets were assessed using atomic force…”
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