Search Results - "Elfar, John"

Peripheral nerve injury and myelination: Potential therapeutic strategies by Modrak, Max, Talukder, M. A. Hassan, Gurgenashvili, Khatuna, Noble, Mark, Elfar, John C.

“…Traumatic peripheral nerve injury represents a major clinical and public health problem that often leads to significant functional impairment and permanent…”
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Erythropoietin promotes M2 macrophage phagocytosis of Schwann cells in peripheral nerve injury by Govindappa, Prem Kumar, Elfar, John C.

“…Following acute sciatic nerve crush injury (SNCI), inflammation and the improper phagocytic clearance of dying Schwann cells (SCs) has effects on remodeling…”
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Erythropoietin M2 macrophage Signaling Promotes Schwann Cells Clearance and Functional Recovery Following Peripheral Nerve Injury by Govindappa, Prem Kumar, Elfar, John C.

“…Background Traumatic peripheral nerve injury (TPNI) obliterates axons and Schwann cells (SCs) that must be cleared through phagocytosis to allow surviving SCs…”
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Length of hospital stay after hip fracture and risk of early mortality after discharge in New York state: retrospective cohort study by Nikkel, Lucas E, Kates, Stephen L, Schreck, Michael, Maceroli, Michael, Mahmood, Bilal, Elfar, John C

“…Study question Can the length of hospital stay for hip fracture affect a patient’s risk of death 30 days after discharge?Methods In a retrospective cohort…”
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Nerve physiology: mechanisms of injury and recovery by Menorca, Ron M G, Fussell, Theron S, Elfar, John C

“…Peripheral nerve injuries are common conditions, with broad-ranging groups of symptoms depending on the severity and nerves involved. Although much knowledge…”
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Composite Bone Models in Orthopaedic Surgery Research and Education by Elfar, J., Menorca, R. M. G., Reed, J. D., Stanbury, S.

“…Composite bone models are increasingly used in orthopaedic biomechanics research and surgical education--applications that traditionally relied on cadavers…”
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Elbow Instability: Anatomy, Biomechanics, Diagnostic Maneuvers, and Testing by Karbach, Lauren E., MD, Elfar, John, MD

“…The elbow comprises a complex of bony and ligamentous stabilizers that provide both primary and secondary constraints to elbow instability. Through trauma and…”
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A critical role for erythropoietin on vagus nerve Schwann cells in intestinal motility by Govindappa, Prem Kumar, Begom, Mosammat, Gupta, Yash, Elfar, John C, Rawat, Manmeet, Elfar, Walaa

“…Dysmotility and postoperative ileus (POI) are frequent major clinical problems post-abdominal surgery. Erythropoietin (EPO) is a multifunctional…”
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Priming the stump in peripheral nerve injury (Commentary on Zhang et al. (2017)) by Elfar, John C.

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Aberrant structure of fibrillar collagen and elevated levels of advanced glycation end products typify delayed fracture healing in the diet-induced obesity mouse model by Khajuria, Deepak Kumar, Soliman, Marwa, Elfar, John C., Lewis, Gregory S., Abraham, Thomas, Kamal, Fadia, Elbarbary, Reyad A.

“…Impaired fracture healing in patients with obesity-associated type 2 diabetes (T2D) is a significant unmet clinical problem that affects millions of people…”
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Zoledronic Acid Improves Muscle Function in Healthy Mice Treated with Chemotherapy by Hain, Brian A, Jude, Baptiste, Xu, Haifang, Smuin, Dallas M, Fox, Edward J, Elfar, John C, Waning, David L

“…ABSTRACT Carboplatin is a chemotherapy drug used to treat solid tumors but also causes bone loss and muscle atrophy and weakness. Bone loss contributes to…”
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Shear wave elastography of transverse carpal ligament increased with simulated carpal tunnel pressure by Zhang, Hui, Elfar, John C, Kwoh, C Kent, Li, Zong-Ming

“…Elevation of carpal tunnel pressure is known to be associated with carpal tunnel syndrome. This study aimed to correlate the shear wave elastography in the…”
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National trends in the management of central cord syndrome: an analysis of 16,134 patients by Brodell, David W., BA, Jain, Amit, MD, Elfar, John C., MD, Mesfin, Addisu, MD

“…Abstract Background context Central cord syndrome (CCS) is a common cause of incomplete spinal cord injury. However, to date, national trends in the management…”
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Correction: 4-Aminopyridine treatment for nerve injury resulting from radical retro-pubic prostatectomy: a single-center double-blind, randomized, placebo-controlled study by Ghazi, Ahmed, Osinski, Thomas L, Feng, Changyong, Horne, Andrea, Elfar, John

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Advancements in Custom 3D-Printed Titanium Interbody Spinal Fusion Cages and Their Relevance in Personalized Spine Care by Lewandrowski, Kai-Uwe, Vira, Shaleen, Elfar, John C, Lorio, Morgan P

“…3D-printing technology has revolutionized spinal implant manufacturing, particularly in developing personalized and custom-fit titanium interbody fusion cages…”
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4-Aminopyridine treatment for nerve injury resulting from radical retro-pubic prostatectomy: a single-center double-blind, randomized, placebo-controlled study by Ghazi, Ahmed, Osinski, Thomas L, Feng, Changyong, Horne, Andrea, Elfar, John

“…Prostate cancer (PCa) is the most common non-cutaneous malignancy in men and leads to the second most common cause of cancer related mortality in men. Early…”
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Effects of 4-Aminopyridine on Combined Nerve and Muscle Injury and Bone Loss by Govindappa, Prem Kumar, Jagadeeshaprasad, Mashanipalya G., Tortora, Peter, Talukder, M. A. Hassan, Elfar, John C.

“…Musculoskeletal injuries are common, and peripheral nerve injury (PNI) causes significant muscle and bone loss within weeks. After PNI, 4-aminopyridine (4-AP)…”
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Non-surgical treatment of lateral epicondylitis: a systematic review of randomized controlled trials by Sims, Susan E. G., Miller, Katherine, Elfar, John C., Hammert, Warren C.

“…Background Non-surgical approaches to treatment of lateral epicondylitis are numerous. The aim of this systematic review is to examine randomized, controlled…”
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A novel nerve transection and repair method in mice: histomorphometric analysis of nerves, blood vessels, and muscles with functional recovery by Lee, Jung Il, Gurjar, Anagha A., Talukder, M. A. Hassan, Rodenhouse, Andrew, Manto, Kristen, O’Brien, Mary, Govindappa, Prem Kumar, Elfar, John C.

“…Peripheral nerve transection is associated with permanent functional deficit even after advanced microsurgical repair. While it is difficult to investigate the…”
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4‐Aminopyridine attenuates muscle atrophy after sciatic nerve crush injury in mice by Yue, Li, Talukder, M. A. Hassan, Gurjar, Anagha, Lee, Jung Il, Noble, Mark, Dirksen, Robert T., Chakkalakal, Joe, Elfar, John C.

“…ABSTRACT Introduction We recently demonstrated the beneficial effects of 4‐aminopyridine (4‐AP), a potassium channel blocker, in enhancing remyelination and…”
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