Search Results - "Elena, K."

Small Molecules with Spiro-Conjugated Cycles: Advances in Synthesis and Applications by Beloglazkina, Elena K

“…Dear Colleagues, [...]…”
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Long-term effects of radiation exposure on health by Kamiya, Kenji, Prof, Ozasa, Kotaro, MD, Akiba, Suminori, Prof, Niwa, Ohstura, Prof, Kodama, Kazunori, MD, Takamura, Noboru, Prof, Zaharieva, Elena K, PhD, Kimura, Yuko, MD, Wakeford, Richard, Prof

“…Summary Late-onset effects of exposure to ionising radiation on the human body have been identified by long-term, large-scale epidemiological studies. The…”
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From the soil to the clinic: the impact of microbial secondary metabolites on antibiotic tolerance and resistance by Perry, Elena K., Meirelles, Lucas A., Newman, Dianne K.

“…Secondary metabolites profoundly affect microbial physiology, metabolism and stress responses. Increasing evidence suggests that these molecules can modulate…”
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Health impacts of bushfire smoke exposure in Australia by Walter, Clare M., Schneider‐Futschik, Elena K., Knibbs, Luke D., Irving, Louis B.

“…ABSTRACT Smoke exposure from bushfires, such as those experienced in Australia during 2019–2020, can reach levels up to 10 times those deemed hazardous…”
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Extent of foetal exposure to maternal elexacaftor/tezacaftor/ivacaftor during pregnancy by Li, Danni, Donnelley, Martin, Parsons, David, Habgood, Mark D., Schneider‐Futschik, Elena K.

“…Background and Purpose Cystic fibrosis (CF) patients are living longer and healthier due to improved treatments, e.g. cystic fibrosis transmembrane conductance…”
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A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping by Rao, Suhas S.P., Huntley, Miriam H., Durand, Neva C., Stamenova, Elena K., Bochkov, Ivan D., Robinson, James T., Sanborn, Adrian L., Machol, Ido, Omer, Arina D., Lander, Eric S., Aiden, Erez Lieberman

“…We use in situ Hi-C to probe the 3D architecture of genomes, constructing haploid and diploid maps of nine cell types. The densest, in human lymphoblastoid…”
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Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations by Fulco, Charles P., Nasser, Joseph, Jones, Thouis R., Munson, Glen, Bergman, Drew T., Subramanian, Vidya, Grossman, Sharon R., Anyoha, Rockwell, Doughty, Benjamin R., Patwardhan, Tejal A., Nguyen, Tung H., Kane, Michael, Perez, Elizabeth M., Durand, Neva C., Lareau, Caleb A., Stamenova, Elena K., Aiden, Erez Lieberman, Lander, Eric S., Engreitz, Jesse M.

“…Enhancer elements in the human genome control how genes are expressed in specific cell types and harbor thousands of genetic variants that influence risk for…”
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Protein Engineering: Advances in Phage Display for Basic Science and Medical Research by Davydova, Elena K.

“…Functional Protein Engineering became the hallmark in biomolecule manipulation in the new millennium, building on and surpassing the underlying structural DNA…”
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Melanin Pigment in Plants: Current Knowledge and Future Perspectives by Glagoleva, Anastasiia Y., Shoeva, Olesya Y., Khlestkina, Elena K.

“…The word “melanin” refers to a group of high molecular weight, black, and brown pigments formed through the oxidation and polymerization of phenolic compounds…”
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Silica-coated calcium phosphate nanoparticles for gene silencing of NF-κB p65 by siRNA and their impact on cellular players of inflammation by Białas, Nataniel, Müller, Elena K., Epple, Matthias, Hilger, Ingrid

“…The transcription factor NF-κB and its signaling cascade both play key roles in all inflammatory processes. The most critical member of the NF-κB transcription…”
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Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes by Sanborn, Adrian L., Rao, Suhas S. P., Huang, Su-Chen, Durand, Neva C., Huntley, Miriam H., Jewett, Andrew I., Bochkov, Ivan D., Chinnappan, Dharmaraj, Cutkosky, Ashok, Li, Jian, Geeting, Kristopher P., Gnirke, Andreas, Melnikov, Alexandre, McKenna, Doug, Stamenova, Elena K., Lander, Eric S., Aiden, Erez Lieberman

“…We recently used in situ Hi-C to create kilobase-resolution 3D maps of mammalian genomes. Here, we combine these maps with new Hi-C, microscopy, and…”
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DNA methylation from a Type I restriction modification system influences gene expression and virulence in Streptococcus pyogenes by Nye, Taylor M, Jacob, Kristin M, Holley, Elena K, Nevarez, Juan M, Dawid, Suzanne, Simmons, Lyle A, Watson, Jr, Michael E

“…DNA methylation is pervasive across all domains of life. In bacteria, the presence of N6-methyladenosine (m6A) has been detected among diverse species, yet the…”
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Beyond cystic fibrosis transmembrane conductance regulator therapy: a perspective on gene therapy and small molecule treatment for cystic fibrosis by Schneider-Futschik, Elena K.

“…Cystic fibrosis (CF) is a life-limiting disease caused by defective or deficient cystic fibrosis transmembrane conductance regulator (CFTR) activity. The…”
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The Lysin Motif Receptor-like Kinase (LysM-RLK) CERK1 Is a Major Chitin-binding Protein in Arabidopsis thaliana and Subject to Chitin-induced Phosphorylation by Petutschnig, Elena K., Jones, Alexandra M.E., Serazetdinova, Liliya, Lipka, Ulrike, Lipka, Volker

“…Plants detect potential pathogens by sensing microbe-associated molecular patterns via pattern recognition receptors. In the dicot model plant Arabidopsis, the…”
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Single-cell topological RNA-seq analysis reveals insights into cellular differentiation and development by Rizvi, Abbas H, Camara, Pablo G, Kandror, Elena K, Roberts, Thomas J, Schieren, Ira, Maniatis, Tom, Rabadan, Raul

“…Analysis of RNA-seq data from individual developing mouse motor neuron cells with topological data analysis sheds light on crucial cell-fate decisions during…”
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Antibiotic-non-antibiotic combinations for combating extremely drug-resistant Gram-negative 'superbugs' by Schneider, Elena K, Reyes-Ortega, Felisa, Velkov, Tony, Li, Jian

“…The emergence of antimicrobial resistance of Gram-negative pathogens has become a worldwide crisis. The status quo for combating resistance is to employ…”
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Bacterial biofilms in the human body: prevalence and impacts on health and disease by Perry, Elena K., Tan, Man-Wah

“…Bacterial biofilms can be found in most environments on our planet, and the human body is no exception. Consisting of microbial cells encased in a matrix of…”
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Advantages and Disadvantages of Using Magnetic Nanoparticles for the Treatment of Complicated Ocular Disorders by Schneider-Futschik, Elena K, Reyes-Ortega, Felisa

“…Nanomaterials provide enormous opportunities to overcome the limitations of conventional ocular delivery systems, such as low therapeutic efficacy, side…”
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Synthesis and structure−activity relationships of teixobactin by Karas, John A., Chen, Fan, Schneider‐Futschik, Elena K., Kang, Zhisen, Hussein, Maytham, Swarbrick, James, Hoyer, Daniel, Giltrap, Andrew M., Payne, Richard J., Li, Jian, Velkov, Tony

“…The discovery of antibiotics has led to the effective treatment of bacterial infections that were otherwise fatal and has had a transformative effect on modern…”
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Cytochrome P450 3A4 Induction: Lumacaftor versus Ivacaftor Potentially Resulting in Significantly Reduced Plasma Concentration of Ivacaftor by Schneider, Elena K

“…Since the release of ivacaftor-lumacaftor, several red-flags have been raised that highlight the clinical efficacy of this combination strategy that may be…”
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