Search Results - "Elemam, Noha M"
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The response of salivary proinflammatory biomarkers to tooth extraction in individuals with type II diabetes mellitus
Published in BMC oral health (19-02-2024)“…This study investigated the levels of salivary proinflammatory cytokines in the saliva of patients living with type II diabetes mellitus (DM) compared to those…”
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Insulin-like growth factor family and prostate cancer: new insights and emerging opportunities
Published in Frontiers in endocrinology (Lausanne) (30-05-2024)“…Prostate cancer is the second most commonly diagnosed cancer in men. The mammalian insulin-like growth factor (IGF) family is made up of three ligands (IGF-I,…”
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Checkpoint molecules on infiltrating immune cells in colorectal tumor microenvironment
Published in Frontiers in medicine (22-08-2022)“…Colorectal cancer (CRC) is one of the most prevalent cancer types worldwide, with a high mortality rate due to metastasis. The tumor microenvironment (TME)…”
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4
Ozone Therapy in Medicine and Dentistry: A Review of the Literature
Published in Dentistry journal (01-08-2023)“…Ozone has been successfully used in medicine for over 100 years due to its microbiological qualities. Its powerful oxidation impact, which results in the…”
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A Novel Epigenetic Strategy to Concurrently Block Immune Checkpoints PD-1/PD-L1 and CD155/TIGIT in Hepatocellular Carcinoma
Published in Translational oncology (01-07-2024)“…•PDL1, CD155, PD-1 and TIGIT are upregulated in liver tissues and PBMCs of HCC patients, respectively.•CCAT-1, H19, and MALAT-1 are significantly upregulated…”
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Identifying Immunological and Clinical Predictors of COVID-19 Severity and Sequelae by Mathematical Modeling
Published in Frontiers in immunology (20-04-2022)“…Since its emergence as a pandemic in March 2020, coronavirus disease (COVID-19) outcome has been explored several predictive models, using specific clinical or…”
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Association of specific ACE2 and TMPRSS2 variants with circulatory cytokines of COVID-19 Emirati patients
Published in Frontiers in immunology (24-05-2024)“…The COVID-19 pandemic represented one of the most significant challenges to researchers and healthcare providers. Several factors determine the disease…”
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The Beneficial and Debilitating Effects of Environmental and Microbial Toxins, Drugs, Organic Solvents and Heavy Metals on the Onset and Progression of Multiple Sclerosis
Published in Toxins (05-03-2019)“…Multiple sclerosis (MS), a chronic inflammatory disease of the central nervous system is common amongst young adults, leading to major personal and…”
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MIAT LncRNA: A multifunctional key player in non-oncological pathological conditions
Published in Non-coding RNA research (01-06-2024)“…The discovery of non-coding RNAs (ncRNAs) has unveiled a wide range of transcripts that do not encode proteins but play key roles in several cellular and…”
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Evaluating Risk: Benefit Ratio of Fat-Soluble Vitamin Supplementation to SARS-CoV-2-Infected Autoimmune and Cancer Patients: Do Vitamin-Drug Interactions Exist?
Published in Life (Basel, Switzerland) (20-10-2022)“…COVID-19 is a recent pandemic that mandated the scientific society to provide effective evidence-based therapeutic approaches for the prevention and treatment…”
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Are embryonic stem cell markers and ALDH1A1 relevant in the context of breast cancer estrogen positivity?
Published in Cancer medicine (Malden, MA) (01-02-2024)“…Background Embryonic pluripotency markers are recognized for their role in ER− BC aggressiveness, but their significance in ER+ BC remains unclear. This study…”
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Reduced Expression of PLCXD3 Associates With Disruption of Glucose Sensing and Insulin Signaling in Pancreatic β-Cells
Published in Frontiers in endocrinology (Lausanne) (06-11-2019)“…Previous work has shown that reduced expression of PLCXD3 , a member of the phosphoinositide-specific phospholipases (PI-PLC) family, impaired insulin…”
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Expression of immune checkpoints (PD-L1 and IDO) and tumour-infiltrating lymphocytes in breast cancer
Published in Heliyon (01-09-2022)“…Breast cancer (BC) has become the most common cancer globally in 2020 as well as in the United Arab Emirates. The breast tumor microenvironment is composed of…”
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Pyroptosis: The missing puzzle among innate and adaptive immunity crosstalk
Published in Journal of leukocyte biology (01-07-2020)“…Pyroptosis is a newly discovered programmed cell death with inflammasome formation. Pattern recognition receptors that identify repetitive motifs of…”
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Expression Status of Proton Sensing Receptor GPR68 in Various Breast Cancer Molecular Subtypes
Published in The FASEB journal (01-05-2022)“…Background and aim Breast cancer has become the most diagnosed cancer and the leading cause of global cancer incidence in 2020. It is quite known that highly…”
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CD68, CD86 and CD163 Expression Profile in Breast Cancer Molecular Subtypes
Published in The FASEB journal (01-05-2022)“…Background and aim Breast cancer (BC) is the second most common global cause of cancer deaths among women. Several immune cells are identified in the tumor…”
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Pharmacogenomic and epigenomic approaches to untangle the enigma of IL-10 blockade in oncology
Published in Expert reviews in molecular medicine (08-01-2024)“…The host immune system status remains an unresolved mystery among several malignancies. An immune-compromised state or smart immune-surveillance tactics…”
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Disrupting of family with sequence similarity 105, member A (Fam105a) deteriorates pancreatic β-cell physiology and insulin secretion in INS-1 cells
Published in Molecular and cellular endocrinology (20-08-2023)“…The role of “Family with sequence similarity 105, member A” (FAM105A) in pancreatic β-cell function in relation to type 2 diabetes mellitus (T2D) is not fully…”
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Simvastatin reduced infiltration of memory subsets of T lymphocytes in the lung tissue during Th2 allergic inflammation
Published in International immunopharmacology (01-12-2022)“…•Lymphocytes infiltration is a key mechanism that drives asthma lung inflammation.•Simvastatin decreases infiltration of TEM and TCM cells into OVA-sensitized…”
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A single centered study reveals association between liver injury and COVID-19 infection
Published in Saudi journal of biological sciences (01-10-2021)“…Despite the fact that it has been over a year with the pandemic COVID-19 infection, ongoing research and analysis reveal many complications and comorbidities…”
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