Search Results - "Elding Larsson, H."
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Pancreas volume and fat fraction in children with Type 1 diabetes
Published in Diabetic medicine (01-10-2016)“…Aims People with Type 1 diabetes have smaller pancreases than healthy individuals. Several diseases causing pancreatic atrophy are associated with pancreatic…”
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The Better Diabetes Diagnosis (BDD) study – A review of a nationwide prospective cohort study in Sweden
Published in Diabetes research and clinical practice (01-06-2018)“…The incidence of type 1 diabetes (T1D) in Sweden is one of the highest in the world. However, the possibility of other types of diabetes must also be…”
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Reduced display of conformational epitopes in the N‐terminal truncated GAD65 isoform: relevance for people with stiff person syndrome or DQ8/8‐positive Type 1 diabetes mellitus
Published in Diabetic medicine (01-11-2019)“…Aims To investigate whether the N‐terminal truncated glutamic acid decarboxylase 65 (GAD65) isoform is as well recognized by people with stiff person syndrome…”
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Thyroid autoimmunity in relation to islet autoantibodies and HLA-DQ genotype in newly diagnosed type 1 diabetes in children and adolescents
Published in Diabetologia (01-08-2013)“…Aims/hypothesis The aim of this work was to investigate, in children newly diagnosed with type 1 diabetes: (1) the prevalence of autoantibodies against thyroid…”
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Serological evaluation of possible exposure to Ljungan virus and related parechovirus in autoimmune (type 1) diabetes in children
Published in Journal of medical virology (01-07-2015)“…Exposure to Ljungan virus (LV) is implicated in the risk of autoimmune (type 1) diabetes but possible contribution by other parechoviruses is not ruled out…”
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The three ZNT8 autoantibody variants together improve the diagnostic sensitivity of childhood and adolescent type 1 diabetes
Published in Autoimmunity (Chur, Switzerland) (01-08-2011)“…Aims: We tested whether autoantibodies to all three ZnT8RWQ variants, GAD65, insulinoma-associated protein 2 (IA-2), insulin and autoantibodies to islet cell…”
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Triple specificity of ZnT8 autoantibodies in relation to HLA and other islet autoantibodies in childhood and adolescent type 1 diabetes
Published in Pediatric diabetes (01-03-2013)“…Objective To establish the diagnostic sensitivity of and the relationships between autoantibodies to all three Zinc transporter 8 (Zinc transporter 8…”
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Children developing type 1 diabetes before 6 years of age have increased linear growth independent of HLA genotypes
Published in Diabetologia (01-09-2008)“…Aims/hypothesis High birthweight and increased childhood growth are risk factors for type 1 diabetes. Relative birthweight is associated with HLA genotypes…”
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Doubly Reactive INS‐IGF2 Autoantibodies in Children with Newly Diagnosed Autoimmune (type 1) Diabetes
Published in Scandinavian journal of immunology (01-10-2015)“…The splice variant INS‐IGF2 entails the preproinsulin signal peptide, the insulin B‐chain, eight amino acids of the C‐peptide and 138 unique amino acids from…”
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Absence of Islet Autoantibodies and Modestly Raised Glucose Values at Diabetes Diagnosis Should Lead to Testing for MODY: Lessons From a 5-Year Pediatric Swedish National Cohort Study
Published in Diabetes care (01-01-2020)“…Identifying maturity-onset diabetes of the young (MODY) in pediatric populations close to diabetes diagnosis is difficult. Misdiagnosis and unnecessary insulin…”
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Zinc transporter 8 autoantibodies and their association with SLC30A8 and HLA-DQ genes differ between immigrant and Swedish patients with newly diagnosed type 1 diabetes in the Better Diabetes Diagnosis study
Published in Diabetes (New York, N.Y.) (01-10-2012)“…We examined whether zinc transporter 8 autoantibodies (ZnT8A; arginine ZnT8-RA, tryptophan ZnT8-WA, and glutamine ZnT8-QA variants) differed between immigrant…”
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A novel triple mix radiobinding assay for the three ZnT8 (ZnT8-RWQ) autoantibody variants in children with newly diagnosed diabetes
Published in Journal of immunological methods (2011)“…Autoantibodies against the zinc transporter 8 (ZnT8A) are common in type 1 diabetes (T1D). ZnT8A analyses are complicated by the fact that there are three…”
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Antibodies to Influenza Virus A/H1N1 Hemagglutinin in Type 1 Diabetes Children Diagnosed Before, During and After the SWEDISH A(H1N1)pdm09 Vaccination Campaign 2009–2010
Published in Scandinavian journal of immunology (01-02-2014)“…We determined A/H1N1‐hemagglutinin (HA) antibodies in relation to HLA‐DQ genotypes and islet autoantibodies at clinical diagnosis in 1141 incident 0.7‐to…”
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Next-Generation HLA Sequence Analysis Uncovers Seven HLA-DQ Amino Acid Residues and Six Motifs Resistant to Childhood Type 1 Diabetes
Published in Diabetes (New York, N.Y.) (01-11-2020)“…HLA-DQA1 and -DQB1 genes have significant and potentially causal associations with autoimmune type 1 diabetes (T1D). To follow up on the earlier analysis on…”
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Reduced display of conformational epitopes in the N‐terminal truncated GAD 65 isoform: relevance for people with stiff person syndrome or DQ 8/8‐positive Type 1 diabetes mellitus
Published in Diabetic medicine (01-11-2019)“…Abstract Aims To investigate whether the N‐terminal truncated glutamic acid decarboxylase 65 ( GAD 65) isoform is as well recognized by people with stiff…”
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Eleven Amino Acids of HLA-DRB1 and Fifteen Amino Acids of HLA-DRB3, 4, and 5 Include Potentially Causal Residues Responsible for the Risk of Childhood Type 1 Diabetes
Published in Diabetes (New York, N.Y.) (01-08-2019)“…Next-generation targeted sequencing of HLA-DRB1 and HLA-DRB3, -DRB4, and -DRB5 (abbreviated as DRB345) provides high resolution of functional variant positions…”
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NPY minor autoantibodies in newly diagnosed type 1 diabetes patients
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Antibody Affinity Against 2009 A/H1N1 Influenza and Pandemrix Vaccine Nucleoproteins Differs Between Childhood Narcolepsy Patients and Controls
Published in Viral immunology (01-10-2017)“…Increased narcolepsy incidence was observed in Sweden following the 2009 influenza vaccination with Pandemrix . A substitution of the 2009 nucleoprotein for…”
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Doubly Reactive INS ‐ IGF 2 Autoantibodies in Children with Newly Diagnosed Autoimmune (type 1) Diabetes
Published in Scandinavian journal of immunology (01-10-2015)“…Abstract The splice variant INS ‐ IGF 2 entails the preproinsulin signal peptide, the insulin B‐chain, eight amino acids of the C‐peptide and 138 unique amino…”
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Journal Article