Search Results - "Elder, J D"

Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer by Vincent, E E, Elder, D J E, Thomas, E C, Phillips, L, Morgan, C, Pawade, J, Sohail, M, May, M T, Hetzel, M R, Tavaré, J M

“…Background: The activity of the protein kinase Akt is frequently dysregulated in cancer and is an important factor in the growth and survival of tumour cells…”
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Modelling of beryllium erosion–redeposition on ITER first wall panels by Carpentier, S., Pitts, R.A., Stangeby, P.C., Elder, J.D., Kukushkin, A.S., Lisgo, S., Fundamenski, W., Moulton, D.

“…Unlike any current operating tokamak, ITER will operate long pulse, high performance discharges with an almost conformal, shaped and full beryllium first wall…”
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Recent DIII-D progress toward validating models of tungsten erosion, re-deposition, and migration for application to next-step fusion devices by Abrams, T, Guterl, J G, Abe, S, Donovan, D C, Bykov, I, Johnson, C A, Nichols, J H, Elder, J D, Ennis, D A, Loch, S D, Rudakov, D L, Sinclair, G, Skinner, C H, Stangeby, P C, Thomas, D M, Unterberg, E A, Wampler, W R

“…Abstract Fundamental mechanisms governing the erosion and prompt re-deposition of tungsten impurities in tokamak divertors are identified and analyzed to…”
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Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression by ELDER, D. J. E, HALTON, D. E, HAGUE, A, PARASKEVA, C

“…Cyclooxygenase (COX) catalyzes the conversion of arachidonic acid to prostaglandin H2. The inducible isoform, COX-2, promotes colorectal tumorigenesis, and…”
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Is community-acquired pneumonia an independent risk factor for cardiovascular disease? by SINGANAYAGAM, A, SINGANAYAGAM, A, ELDER, D. H. J, CHALMERS, J. D

“…Community-acquired pneumonia (CAP) is the most frequent infectious cause of death in western countries. The high mortality rate in CAP is commonly related to…”
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3D-DIVIMP(HC) code modeling of DIII-D DiMES porous plug injector experiments by Mu, Y., Elder, J.D., Stangeby, P.C., McLean, A.G.

“…A Porous Plug Injector (PPI) system for the Divertor Material Evaluation System (DiMES) on DIII-D has been employed for in situ study of chemical erosion in…”
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AMY1 Gene Copy Number Correlates With Glucose Absorption and Visceral Fat Volume, but Not with Insulin Resistance by Barber, Thomas M, Bhatti, Ahsan A, Elder, Patrick J D, Ball, Sarah P, Calvez, Ronan, Ramsden, David B, Cuthbertson, Dan J, Pfeiffer, Andreas F, Burnett, David, Weickert, Martin O

“…Abstract Background The human amylase gene (AMY1) has a broad copy number (CN) variation that may associate with body mass index. Methods Deoxyribonucleic acid…”
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Evaluation of the impact of divertor closure on high-Z material transport and leakage in small angle slot divertor with toroidal tungsten rings in DIII-D by Ma, X, Abrams, T, Covele, B, Elder, J D, Guo, H Y, Guterl, J, Stangeby, P C

“…Predictive modeling of the closed Small Angle Slot (SAS) divertor with toroidal tungsten (W) rings in different poloidal locations is conducted to evaluate the…”
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Design and physics basis for the upcoming DIII-D SAS-VW campaign to quantify tungsten leakage and transport in a new slot divertor geometry by Abrams, T, Sinclair, G, Nichols, J H, Unterberg, E A, Donovan, D C, Duran, J, Elder, J D, Glass, F, Grierson, B A, Guo, H Y, Hall, T, Ma, X, Maurizio, R, McLean, A G, Murphy, C, Nguyen, R, Rudakov, D L, Stangeby, P C, Thomas, D M, Zamperini, S A

“…Abstract A set of experiments are planned to exploit the high SOL collisionality enabled by a tightly baffled slot divertor geometry to suppress tungsten…”
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Interaction of laminate damage and adhesive disbonding in composite scarf joints subjected to combined in-plane loading and impact by Kim, M.K., Elder, D.J., Wang, C.H., Feih, S.

“…Impact tests were carried out on composite laminates and composite scarf repairs, while both were subjected to in-plane loading with tensile pre-strain levels…”
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3D-DIVIMP-HC modeling analysis of methane injection into DIII-D using the DiMES porous plug injector by Mu, Y., McLean, A.G., Elder, J.D., Stangeby, P.C., Bray, B.D., Brooks, N.H., Davis, J.W., Fenstermacher, M.E., Groth, M., Lasnier, C.J., Rudakov, D.L., Watkins, J.G., West, W.P., Wong, C.P.C.

“…A self-contained gas injection system for the Divertor Material Evaluation System (DiMES) on DIII-D, the porous plug injector (PPI), has been employed for in…”
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Spectroscopic characterization and simulation of chemical sputtering using the DiMES porous plug injector in DIII-D by McLean, A.G., Davis, J.W., Stangeby, P.C., Brooks, N.H., Whyte, D.G., Allen, S.L., Bray, B.D., Brezinsek, S., Elder, J.D., Fenstermacher, M.E., Groth, M., Haasz, A.A., Hollmann, E.M., Isler, R.C., Lasnier, C.J., Rudakov, D.L., Watkins, J.G., West, W.P., Wong, C.P.C.

“…A self-contained gas injection system for the Divertor Material Evaluation System (DiMES) on DIII-D has been employed for in situ study of chemical erosion in…”
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Measurements of the average energy of carbon atoms released from breakup of methane in the main SOL of DIII-D compared with DIVIMP code modeling by Stangeby, P.C., McLean, A.G., Elder, J.D., Brooks, N.H., West, W.P., Reiter, D.

“…13CH4 , 12CD4 or 12CH4 gases were puffed into the crown (top) of lower single-null divertor plasmas in DIII-D using toroidally symmetric injection,…”
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Net versus gross erosion of silicon carbide in DIII-D divertor by Rudakov, D L, Wampler, W R, Abrams, T, Ding, R, Boedo, J A, Bringuier, S, Bykov, I, Chrobak, C P, Elder, J D, Guo, H Y, Lasnier, C J, Mathison, E, McLean, A G, Sinclair, G, Stangeby, P C, Thomas, D M, Unterberg, E A, Wang, H, Watkins, J G

“…Gross and net erosion rates of silicon from silicon carbide (SiC) coatings were measured in the divertor of DIII-D under well diagnosed reactor-relevant plasma…”
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Analysis of a tungsten sputtering experiment in DIII-D and code/data validation of high redeposition/reduced erosion by Brooks, J.N., Elder, J.D., McLean, A.G., Rudakov, D.L., Stangeby, P.C., Wampler, W.R.

“…We analyze a DIII-D tokamak experiment where two tungsten spots on the removable DiMES divertor probe were exposed to 12s of attached plasma conditions, with…”
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Models of SOL transport and their relation to scaling of the divertor heat flux width in DIII-D by Makowski, M.A., Lasnier, C.J., Leonard, A.W., Osborne, T.H., Umansky, M., Elder, J.D., Nichols, J.H., Stangeby, P.C., Baver, D.A., Myra, J.R.

“…Strong support for the critical pressure gradient model for the heat flux width has been obtained, in that the measured separatrix pressure gradient lies below…”
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ERO code benchmarking of ITER first wall beryllium erosion/re-deposition against LIM predictions by Borodin, D, Kirschner, A, Carpentier-Chouchana, S, Pitts, R A, Lisgo, S, Björkas, C, Stangeby, P C, Elder, J D, Galonska, A, Matveev, D, Philipps, V, Samm, U

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Net versus gross erosion of high-Z materials in the divertor of DIII-D by Rudakov, D L, Stangeby, P C, Wampler, W R, Brooks, J N, Brooks, N H, Elder, J D, Hassanein, A, Leonard, A W, McLean, A G, Moyer, R A, Sizyuk, T, Watkins, J G, Wong, C P C

“…A substantial reduction of net compared to gross erosion of molybdenum and tungsten was observed in experiments conducted in the lower divertor of DIII-D using…”
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Measurements of gross erosion of Al in the DIII-D divertor by Chrobak, C., Stangeby, P.C., Leonard, A.W., Rudakov, D.L., Wong, C.P.C., McLean, A.G., Wright, G.M., Buchenauer, D.A., Watkins, J.G., Wampler, W.R., Elder, J.D., Doerner, R.P., Nishijima, D., Tynan, G.R.

“…Aluminum (Al) is a convenient proxy for beryllium (Be) plasma material interaction studies since they have a number of physical and chemical similarities. Al…”
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OEDGE modeling of DIII-D density scan discharges leading to detachment by Elder, J.D., Stangeby, P.C., Bray, B.D., Brooks, N., Leonard, A.W., McLean, A.G., Unterberg, E.A., Watkins, J.G.

“…The OEDGE code is used to model the outer divertor plasma for discharges from a density scan experiment on DIII-D with the objective of assessing EIRENE and…”
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