Search Results - "Elder, Alan"

In vitro detection of prionemia in TSE-infected cervids and hamsters by Elder, Alan M, Henderson, Davin M, Nalls, Amy V, Wilham, Jason M, Caughey, Byron W, Hoover, Edward A, Kincaid, Anthony E, Bartz, Jason C, Mathiason, Candace K

“…Blood-borne transmission of infectious prions during the symptomatic and asymptomatic stages of disease occurs for both human and animal transmissible…”
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Anoikis resistance in mammary epithelial cells is mediated by semaphorin 7a by Rutherford, Taylor R., Elder, Alan M., Lyons, Traci R.

“…Semaphorin-7a (SEMA7A), best known as a neuroimmune molecule, plays a diverse role in many cellular processes and pathologies. Here, we show that SEMA7A…”
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Semaphorin 7A Promotes Macrophage-Mediated Lymphatic Remodeling during Postpartum Mammary Gland Involution and in Breast Cancer by Elder, Alan M, Tamburini, Beth A J, Crump, Lyndsey S, Black, Sarah A, Wessells, Veronica M, Schedin, Pepper J, Borges, Virginia F, Lyons, Traci R

“…Postpartum mammary gland involution is a tissue remodeling event that occurs in all mammals in the absence of nursing or after weaning to return the gland to…”
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Macphatics and PoEMs in Postpartum Mammary Development and Tumor Progression by Elder, Alan M, Stoller, Alexander R, Black, Sarah A, Lyons, Traci R

“…Postpartum mammary gland involution is a mammalian tissue remodeling event that occurs after pregnancy and lactation to return the gland to the pre-pregnant…”
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457 Semaphorin7a expression in breast cancer promotes susceptibility to immune checkpoint blockade by Elder, Alan, Stoller, Alexander, Kines, Kelsey, Lyons, Traci

“…OBJECTIVES/GOALS: The goal of this study is to decipher the mechanisms by which breast cancers evade the immune system to facilitate metastasis through the…”
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Immediate and Ongoing Detection of Prions in the Blood of Hamsters and Deer following Oral, Nasal, or Blood Inoculations by Elder, Alan M, Henderson, Davin M, Nalls, Amy V, Hoover, Edward A, Kincaid, Anthony E, Bartz, Jason C, Mathiason, Candace K

“…Infectious prions traverse epithelial barriers to gain access to the circulatory system, yet the temporal parameters of transepithelial transport and…”
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Deciphering Pro-Lymphangiogenic Programs during Mammary Involution and Postpartum Breast Cancer by Borges, Virginia F, Elder, Alan M, Lyons, Traci R

“…Postpartum breast cancers are a highly metastatic subset of young women's breast cancers defined as breast cancers diagnosed in the postpartum period or within…”
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PD-1 Blockade During Post-partum Involution Reactivates the Anti-tumor Response and Reduces Lymphatic Vessel Density by Tamburini, Beth A Jirón, Elder, Alan M, Finlon, Jeffrey M, Winter, Andrew B, Wessells, Veronica M, Borges, Virginia F, Lyons, Traci R

“…Post-partum breast cancer patients, or breast cancer patients diagnosed within 10 years of last childbirth, are ~3-5 times more likely to develop metastasis in…”
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Theoretical investigation of the photon efficiency in frequency-domain fluorescence lifetime imaging microscopy by Elder, Alan, Schlachter, Simon, Kaminski, Clemens F

“…We investigate the photon efficiency of frequency-domain fluorescence lifetime imaging microscopy, using both theoretical and Monte Carlo methods. Our analysis…”
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Quantitative Kinetic Analysis in a Microfluidic Device Using Frequency-Domain Fluorescence Lifetime Imaging by Matthews, Sinéad M, Elder, Alan D, Yunus, Kamran, Kaminski, Clemens F, Brennan, Colin M, Fisher, Adrian C

“…A novel microfluidic approach for the quantification of reaction kinetics is presented. A three-dimensional finite difference numerical simulation was…”
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Quantitative fluorescence microscopy techniques by Esposito, Alessandro, Schlachter, Simon, Schierle, Gabriele S Kaminski, Elder, Alan D, Diaspro, Alberto, Wouters, Fred S, Kaminski, Clemens F, Iliev, Asparouh I

“…Fluorescence microscopy is a non-invasive technique that allows high resolution imaging of cytoskeletal structures. Advances in the field of fluorescent…”
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Abstract P1-04-06: Semaphorin7a expression in breast cancers promotes susceptibility to immune checkpoint blockade by Elder, Alan, Stoller, Alexander, Lyons, Traci

“…Five-year survival rates for women diagnosed with stage II breast cancer are >85% on average; however, in women diagnosed with stage II breast cancer (BC)…”
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Abstract 2791: Semaphorin7A and estrogen work in concert to promote mammary tumor growth and alter the immune tumor microenvironment by Elder, Alan, Crump, Lyndsey, Stoller, Alexander, Lyons, Traci

“…Breast cancer (BC) is the 2nd leading cause of cancer-related death in women. Increased lymphatic vessel density (LVD), lymphovascular invasion (LVI), and…”
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Metabolic Alterations Associated with Loss of TET2 Potentiates Inflammation in Myeloid Cells Driving Breast Cancer Progression by Tengesdal, Isak W, Mills, Taylor S, Elder, Alan, Patel, Sweta B, May, Makenna, Schleicher, Wolfang, Marchetti, Carlo, Lyons, Traci, Dinarello, Charles, Pietras, Eric Martin

“…Clonal hematopoiesis of indeterminate potential (CHIP) is characterized by the clonal expansion of hematopoietic stem cells possessing somatic mutations…”
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Abstract B54: Investigating semaphorin 7a in hormone receptor-positive breast cancer progression by Crump, Lyndsey, Elder, Alan, Tarullo, Sarah, Franz, Paris, Lyons, Traci

“…While antiestrogen-based treatments are initially effective for hormone receptor-positive (HR+) breast cancer, these tumors often recur, metastasize, and lose…”
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Abstract PO3-09-05: Potential novel treatments for high-risk subsets of breast cancer in postpartum and African American women by Lyons, Traci, Crump, Lyndsey, Steinmetz, Rachel, Kines, Kelsey, Fairchild, Heather, Elder, Alan

“…Semaphorin 7a (SEMA7A) is a neuroimmune molecule first recognized for its roles in axonal guidance and inflammation. More recently, SEMA7A has emerged as a…”
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Abstract B55: Investigating the role of semaphorin 7a in triple-negative breast cancer cell invasion by Tarullo, Sarah Elizabeth, Elder, Alan, Hill, Ryan, Hansen, Kirk, Lyons, Traci

“…Despite new targeted therapies and improved screening, breast cancer is the second leading cause of cancer-related death of women in the United States. This…”
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ϕ^2FLIM: a technique for alias-free frequency domain fluorescence lifetime imaging by Elder, Alan D., Kaminski, Clemens F., Frank, Jonathan H.

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Detecting the temporal status of blood-borne prions in transmissible spongiform encephalopathy-infected hosts by Elder, Alan Michael

“…Transmissible spongiform encephalopathies (TSEs), or prion diseases, are infectious, fatal neurodegenerative diseases with a protracted subclinical disease…”
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In Vitro Detection of prionemia in TSE-Infected Cervids and Hamsters: e80203 by Elder, Alan M, Henderson, Davin M, Nalls, Amy V, Wilham, Jason M, Caughey, Byron W, Hoover, Edward A, Kincaid, Anthony E, Bartz, Jason C, Mathiason, Candace K

“…Blood-borne transmission of infectious prions during the symptomatic and asymptomatic stages of disease occurs for both human and animal transmissible…”
Get full text