Search Results - "Eldeen, Muhammad Alaa"

Exendin‐4 protects the hearts of rats from ischaemia/reperfusion injury by boosting antioxidant levels and inhibition of JNK/p66Shc/NADPH axis by Eid, Refaat A., Zaki, Mohamed Samir Ahmed, Alaa Eldeen, Muhammad, Alshehri, Majed M., Shati, Ayed A., El‐kott, Attalla Farag

“…Exendin‐4, a glucagon‐like peptide‐1 receptor agonist, was shown to protect against cardiac ischaemia/reperfusion (I/R) injury by suppressing oxidative stress…”
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Cyanidin-3-Glucoside Modulates hsa_circ_0001345/miRNA106b/ATG16L1 Axis Expression as a Potential Protective Mechanism against Hepatocellular Carcinoma by Zabady, Shaimaa, Mahran, Nievin, Soltan, Mohamed A., Alaa Eldeen, Muhammad, Eid, Refaat A., Albogami, Sarah, Fayad, Eman, Matboli, Marwa, Habib, Eman K., Hasanin, Amany H., A. Ali, Mahmoud, Mesbah, Noha M., Abo-Elmatty, Dina M., Abdel-Hamed, Asmaa R.

“…Hepatocellular carcinoma (HCC) is the most common form of malignancy in the liver. Autophagy was found to have a significant effect in controlling HCC…”
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Assessment of Glutathione Peroxidase-1 (GPX1) Gene Expression as a Specific Diagnostic and Prognostic Biomarker in Malignant Pleural Mesothelioma by Gharib, Amal F, Alaa Eldeen, Muhammad, Khalifa, Amany Salah, Elsawy, Wael H, Eed, Emad Mohamed, Askary, Ahmad El, Eid, Refaat A, Soltan, Mohamed A, Raafat, Nermin

“…Malignant pleural mesothelioma (MPM) is a malignant tumor of the mesothelial lining of the thorax. It has been related to frequent exposure to asbestos…”
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Chronic consumption of a high‐fat diet rich in corn oil activates intrinsic cell death pathway and induces several ultrastructural changes in the atria of healthy and type 1 diabetic rat by Eid, Refaat A., Eleawa, Samy M., Alkhateeb, Mahmoud A., Aldera, Hussain, Zaki, Mohamed Samir Ahmed, Al‐Shraim, Mubarak, Saeed, Mansour A., El‐kott, Attalla Farag, Alaa Eldeen, Muhammad, Alassiri, Mohammed, Alshehri, Majed M., Salem Al‐Shudiefat, Abd Al‐Rahman, Khalil, Mohammad A.

“…This study investigates the effect of chronic consumption of a high‐fat diet rich in corn oil (CO‐HFD) on atrial cells ultrastructure, antioxidant levels and…”
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Molecular Epidemiology of Cystic Echinococcosis in Rural Baluchistan, Pakistan: A Cross-Sectional Study by Ullah, Ihsan, Sattar, Sadia, Ali, Ijaz, Farid, Arshad, Ullah, Amin, Eid, Refaat A, Samir A Zaki, Mohamed, Alaa Eldeen, Muhammad, Ahmed, Iftikhar, Ullah, Irfan

“…Cystic echinococcosis (CE), or hydatid cyst disease (HCD), is a zoonosis of significant importance caused by the cestode of (s. l.) that affects mainly nomadic…”
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Proteome Based Approach Defines Candidates for Designing a Multitope Vaccine against the Nipah Virus by Soltan, Mohamed A., Eldeen, Muhammad Alaa, Elbassiouny, Nada, Mohamed, Ibrahim, El-damasy, Dalia A., Fayad, Eman, Abu Ali, Ola A., Raafat, Nermin, Eid, Refaat A., Al-Karmalawy, Ahmed A.

“…Nipah virus is one of the most harmful emerging viruses with deadly effects on both humans and animals. Because of the severe outbreaks, in 2018, the World…”
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Echinops Asteraceae extract guards against malathion-induced liver damage via minimizing oxidative stress, inflammation, and apoptosis by Eid, Refaat A., Abadi, Alsaleem Mohammed, Alghamdi, Mansour A., El-kott, Attalla F., Mohamed, Gamal, Al-Shraim, Mubarak, Alaa Eldeen, Muhammad, Zaki, Mohamed Samir A., Shalaby, Fatma Mohsen

“…Malathion (MAL) is one of the highly toxic organophosphorus (OP) compounds that induces hepatotoxicity. Echinops. ritro leaves extract (ERLE) is traditionally…”
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In Silico Prediction of a Multitope Vaccine against Moraxella catarrhalis: Reverse Vaccinology and Immunoinformatics by Soltan, Mohamed A., Elbassiouny, Nada, Gamal, Helmy, Elkaeed, Eslam B., Eid, Refaat A., Eldeen, Muhammad Alaa, Al-Karmalawy, Ahmed A.

“…Moraxella catarrhalis (M. catarrhalis) is a Gram-negative bacterium that can cause serious respiratory tract infections and middle ear infections in children…”
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Assessment of RACGAP1 as a Prognostic and Immunological Biomarker in Multiple Human Tumors: A Multiomics Analysis by Eid, Refaat A, Soltan, Mohamed A, Eldeen, Muhammad Alaa, Shati, Ayed A, Dawood, Samy A, Eissa, Mohamed, Zaki, Mohamed Samir A, Algahtani, Mohammad, Theyab, Abdulrahman, Abdel-Daim, Mohamed M, Kim, Bonglee

“…Several recent studies have pointed out that arc GTPase activating protein 1 (RACGAP1) is a putative oncogene in many human tumors. However, to date, no…”
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Mining of Marburg Virus Proteome for Designing an Epitope-Based Vaccine by Soltan, Mohamed A., Abdulsahib, Waleed K., Amer, Mahmoud, Refaat, Ahmed M., Bagalagel, Alaa A., Diri, Reem M., Albogami, Sarah, Fayad, Eman, Eid, Refaat A., Sharaf, Sherin M. A., Elhady, Sameh S., Darwish, Khaled M., Eldeen, Muhammad Alaa

“…Marburg virus (MARV) is one of the most harmful zoonotic viruses with deadly effects on both humans and nonhuman primates. Because of its severe outbreaks with…”
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Integrative analysis of WDR12 as a potential prognostic and immunological biomarker in multiple human tumors by Eid, Refaat A, Eldeen, Muhammad Alaa, Soltan, Mohamed A, Al-Shraim, Mubarak, Aldehri, Majed, Alqahtani, Leena S, Alsharif, Ghadi, Albogami, Sarah, Jafri, Ibrahim, Fayad, Eman, Park, Moon Nyeo, Bibi, Shabana, Behairy, Mohammed Y, Kim, Bonglee, Zaki, Mohamed Samir A

“…: Mammalian WD-repeat protein 12 (WDR12), a family member of proteins containing repeats of tryptophan-aspartic acid (WD), is a potential homolog of yeast…”
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Computational Analysis of Deleterious SNPs in NRAS to Assess Their Potential Correlation With Carcinogenesis by Behairy, Mohammed Y., Soltan, Mohamed A., Adam, Mohamed S., Refaat, Ahmed M., Ezz, Ehab M., Albogami, Sarah, Fayad, Eman, Althobaiti, Fayez, Gouda, Ahmed M., Sileem, Ashraf E., Elfaky, Mahmoud A., Darwish, Khaled M., Alaa Eldeen, Muhammad

“…The NRAS gene is a well-known oncogene that acts as a major player in carcinogenesis. Mutations in the NRAS gene have been linked to multiple types of human…”
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Oncogenic Potential of Replication Factor C Subunit 4: Correlations with Tumor Progression and Assessment of Potential Inhibitors by Alaa Eldeen, Muhammad, Mamdouh, Farag, Abdulsahib, Waleed K, Eid, Refaat A, Alhanshani, Ahmad A, Shati, Ayed A, Alqahtani, Youssef A, Alshehri, Mohammed A, Samir A Zaki, Mohamed, Soltan, Mohamed A, Noreldin, Ahmed E

“…Replication Factor C Subunit 4 (RFC4), an oncogene implicated in many human cancers, has yet to be extensively studied in many cancer types to determine its…”
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Factors enhancing the migration and the homing of mesenchymal stem cells in experimentally induced cardiotoxicity in rats by A. Soliman, Nabil, Abd‐Allah, Somia H., Hussein, Samia, Alaa Eldeen, Muhammad

“…Doxorubicin is an effective anti‐neoplastic drug but its use is limited by its cardiotoxicity. Administration of mesenchymal stem cells (MSCs) for the…”
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HBD-2 variants and SARS-CoV-2: New insights into inter-individual susceptibility by Behairy, Mohammed Y, Soltan, Mohamed A, Eldeen, Muhammad Alaa, Abdulhakim, Jawaher A, Alnoman, Maryam M, Abdel-Daim, Mohamed M, Otifi, Hassan, Al-Qahtani, Saleh M, Zaki, Mohamed Samir A, Alsharif, Ghadi, Albogami, Sarah, Jafri, Ibrahim, Fayad, Eman, Darwish, Khaled M, Elhady, Sameh S, Eid, Refaat A

“…A deep understanding of the causes of liability to SARS-CoV-2 is essential to develop new diagnostic tests and therapeutics against this serious virus in order…”
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Integration of Chemoinformatics and Multi-Omics Analysis Defines ECT2 as a Potential Target for Cancer Drug Therapy by Soltan, Mohamed A, Eldeen, Muhammad Alaa, Sajer, Bayan H, Abdelhameed, Reda F A, Al-Salmi, Fawziah A, Fayad, Eman, Jafri, Ibrahim, Ahmed, Hebatallah Emam Mohammed, Eid, Refaat A, Hassan, Hesham M, Al-Shraim, Mubarak, Negm, Amr, Noreldin, Ahmed E, Darwish, Khaled M

“…Epithelial cell transforming 2 (ECT2) is a potential oncogene and a number of recent studies have correlated it with the progression of several human cancers…”
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In Silico Designing of a Multitope Vaccine against Rhizopus microsporus with Potential Activity against Other Mucormycosis Causing Fungi by Soltan, Mohamed A, Eldeen, Muhammad Alaa, Elbassiouny, Nada, Kamel, Hasnaa L, Abdelraheem, Kareem M, El-Gayyed, Hanaa Abd, Gouda, Ahmed M, Sheha, Mohammed F, Fayad, Eman, Ali, Ola A Abu, Ghany, Khalid Abd El, El-Damasy, Dalia A, Darwish, Khaled M, Elhady, Sameh S, Sileem, Ashraf E

“…During the current era of the COVID-19 pandemic, the dissemination of Mucorales has been reported globally, with elevated rates of infection in India, and…”
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Antioxidant Activity of Vitamin C against LPS-Induced Septic Cardiomyopathy by Down-Regulation of Oxidative Stress and Inflammation by Shati, Ayed A, Zaki, Mohamed Samir A, Alqahtani, Youssef A, Al-Qahtani, Saleh M, Haidara, Mohamed A, Dawood, Amal F, AlMohanna, Asmaa M, El-Bidawy, Mahmoud H, Alaa Eldeen, Muhammad, Eid, Refaat A

“…In severe cases of sepsis, endotoxin-induced cardiomyopathy can cause major damage to the heart. This study was designed to see if Vitamin C (Vit C) could…”
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In silico Designing of an Epitope-Based Vaccine Against Common E. coli Pathotypes by Soltan, Mohamed A, Behairy, Mohammed Y, Abdelkader, Mennatallah S, Albogami, Sarah, Fayad, Eman, Eid, Refaat A, Darwish, Khaled M, Elhady, Sameh S, Lotfy, Ahmed M, Alaa Eldeen, Muhammad

“…( ) is a Gram-negative bacterium that belongs to the family Enterobacteriaceae. While can stay as an innocuous resident in the digestive tract, it can cause a…”
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Unraveling Extremely Damaging IRAK4 Variants and Their Potential Implications for IRAK4 Inhibitor Efficacy by Behairy, Mohammed Y, Eid, Refaat A, Otifi, Hassan M, Mohammed, Heitham M, Alshehri, Mohammed A, Asiri, Ashwag, Aldehri, Majed, Zaki, Mohamed Samir A, Darwish, Khaled M, Elhady, Sameh S, El-Shaer, Nahla H, Eldeen, Muhammad Alaa

“…Interleukin-1-receptor-associated kinase 4 (IRAK4) possesses a crucial function in the toll-like receptor (TLR) signaling pathway, and the dysfunction of this…”
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