Search Results - "Elchuri, Sailaja V."
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Identification of dysregulation of sphingolipids in retinoblastoma using liquid chromatography-mass spectrometry
Published in Experimental eye research (01-03-2024)“…Retinoblastoma (RB) is a rare ocular cancer seen in children that counts for approximately 3% of all childhood cancers. It is found that mutation in RB1, a…”
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Non-coding and Coding Transcriptional Profiles Are Significantly Altered in Pediatric Retinoblastoma Tumors
Published in Frontiers in oncology (16-04-2019)“…Retinoblastoma is a rare pediatric tumor of the retina, caused by the homozygous loss of the Retinoblastoma 1 (RB1) tumor suppressor gene. Previous microarray…”
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RNA-Sequencing of Primary Retinoblastoma Tumors Provides New Insights and Challenges Into Tumor Development
Published in Frontiers in genetics (17-05-2018)“…Retinoblastoma is rare tumor of the retina caused by the homozygous loss of the Retinoblastoma 1 tumor suppressor gene (RB1). Loss of the RB1 protein, pRB,…”
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A Comparative Fluorescent Beacon-based Method for Serum microRNA Quantification
Published in Analytical Sciences (2015)“…Circulating serum microRNAs (miRNAs) are promising biomarkers for disease diagnosis. The quantification of the serum miRNA copy number is a challenge due to…”
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Phosphoproteomics of Retinoblastoma: A Pilot Study Identifies Aberrant Kinases
Published in Molecules (Basel, Switzerland) (15-06-2018)“…Retinoblastoma is a malignant tumour of the retina which most often occurs in children. Earlier studies on retinoblastoma have concentrated on the…”
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Characterization and Molecular Mechanism of Peptide-Conjugated Gold Nanoparticle Inhibiting p53-HDM2 Interaction in Retinoblastoma
Published in Molecular therapy. Nucleic acids (15-12-2017)“…Inhibition of the interaction between p53 and HDM2 is an effective therapeutic strategy in cancers that harbor a wild-type p53 protein such as retinoblastoma…”
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Assessment of single nucleotide polymorphisms associated with steroid-induced ocular hypertension
Published in International journal of ophthalmology (18-08-2020)“…To access the association of forty-eight single nucleotide polymorphisms (SNPs) identified from Caucasian population with steroid-induced ocular hypertension…”
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Graphitic Carbon Nitride Causes Widespread Global Molecular Changes in Epithelial and Fibroblast Cells
Published in ACS omega (13-04-2021)“…For scaffold and imaging applications, nanomaterials such as graphene and its derivatives have been widely used. Graphitic carbon nitride (g-C3N4) is among one…”
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A novel method for detection of phosphorylation in single cells by surface enhanced Raman scattering (SERS) using composite organic-inorganic nanoparticles (COINs)
Published in PloS one (15-04-2009)“…Detection of single cell epitopes has been a mainstay of immunophenotyping for over three decades, primarily using fluorescence techniques for quantitation…”
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Synthesis and characterization of surface-enhanced Raman-scattered gold nanoparticles
Published in International journal of nanomedicine (01-01-2013)“…In this paper, we report a simple, rapid, and robust method to synthesize surface-enhanced Raman-scattered gold nanoparticles (GNPs) based on green chemistry…”
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Integrated multi-omics analysis of RB-loss identifies widespread cellular programming and synthetic weaknesses
Published in Communications biology (17-08-2021)“…Inactivation of RB is one of the hallmarks of cancer, however gaps remain in our understanding of how RB-loss changes human cells. Here we show that…”
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Author Correction: Integrated multi-omics analysis of RB-loss identifies widespread cellular programming and synthetic weaknesses
Published in Communications biology (30-09-2021)Get full text
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13
Probing the effect of matrix stiffness in endocytic signalling pathway of corneal epithelium
Published in Biochemical and biophysical research communications (30-04-2020)“…Matrix stiffness regulates the physiology of the cells and plays an important role in maintaining its homeostasis. It has been reported to regulate cell…”
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Vallabhaneni Sita Rama Das, 1933–2010: teacher and mentor
Published in Photosynthesis research (01-05-2016)“…We present here the life and research of V. S. Rama Das, a distinguished Indian botanist who specialized in photosynthesis. He was the first to purify…”
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Computational approaches for identifications of altered ion channels in keratoconus
Published in Eye (London) (17-10-2024)“…Keratoconus is an etiologically complex, degenerative corneal disease that eventually leads to loss of corneal integrity. Cells in corneal epithelium and…”
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Metabolite systems profiling identifies exploitable weaknesses in retinoblastoma
Published in FEBS letters (01-01-2019)“…Retinoblastoma (RB) is a childhood eye cancer. Currently, chemotherapy, local therapy, and enucleation are the main ways in which these tumors are managed. The…”
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Target-specific delivery of doxorubicin to retinoblastoma using epithelial cell adhesion molecule aptamer
Published in Molecular vision (22-11-2012)“…To study target-specific delivery of doxorubicin (Dox) using an RNA aptamer against epithelial cell adhesion molecule (EpCAM) in retinoblastoma (RB) cells. The…”
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18
Molecular Materials through Microdroplets: Synthesis of Protein-Protected Luminescent Clusters of Noble Metals
Published in ACS sustainable chemistry & engineering (29-03-2021)“…Atomically precise noble metal nanoclusters protected with proteins have emerged as a new research frontier in nanoscience due to their unique optical and…”
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Membrane Proteome of Invasive Retinoblastoma: Differential Proteins and Biomarkers
Published in Proteomics. Clinical applications (01-09-2018)“…Purpose: Retinoblastoma (RB) is a pediatric ocular cancer which is caused due to the aberrations in the RB1 gene. The changes in the membrane proteomics would…”
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Proteomic profiling of retinoblastoma by high resolution mass spectrometry
Published in Clinical proteomics (26-10-2016)“…Retinoblastoma is an ocular neoplastic cancer caused primarily due to the mutation/deletion of RB1 gene. Due to the rarity of the disease very limited…”
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