Search Results - "Elboim, Moran"
-
1
Direct recognition of Fusobacterium nucleatum by the NK cell natural cytotoxicity receptor NKp46 aggravates periodontal disease
Published in PLoS pathogens (01-03-2012)“…Periodontitis is a common human chronic inflammatory disease that results in the destruction of the tooth attachment apparatus and tooth loss. Although…”
Get full text
Journal Article -
2
The activating receptor NKp46 is essential for the development of type 1 diabetes
Published in Nature immunology (01-02-2010)“…Natural killer cells infiltrate the pancreas during type 1 diabetes. Mandelboim and co-workers find that the natural killer receptor NKp46 recognizes ligands…”
Get full text
Journal Article -
3
Tumor immunoediting by NKp46
Published in The Journal of immunology (1950) (15-05-2010)“…NK cells interact with a wide variety of hazardous cells including pathogen-infected and tumor cells. NKp46 is a specific NK killer receptor that recognizes…”
Get full text
Journal Article -
4
Enhanced In Vivo Growth of Lymphoma Tumors in the Absence of the NK-Activating Receptor NKp46/NCR1
Published in The Journal of immunology (1950) (15-02-2009)“…The in vitro elimination of virus-infected and tumor cells by NK cells is regulated by a balance between signals conveyed via specific inhibitory and…”
Get full text
Journal Article -
5
Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1
Published in Nature Immunology (01-05-2006)“…The elimination of viruses and tumors by natural killer cells is mediated by specific natural killer cell receptors. To study the in vivo function of a…”
Get full text
Journal Article -
6
Real-world treatment patterns in patients with systemic lupus erythematosus: associations with comorbidities and damage
Published in Lupus science & medicine (24-09-2024)“…ObjectiveTo assess treatment patterns and the association between long-term glucocorticoid (GC) and hydroxychloroquine (HCQ) use and damage accrual in patients…”
Get full text
Journal Article -
7
NKp46 regulates allergic responses
Published in European journal of immunology (01-11-2013)“…Natural killer (NK) cells are cytotoxic cells that are able to rapidly kill viruses, tumor cells, parasites, bacteria, and even cells considered “self”. The…”
Get full text
Journal Article -
8
NK Cell Receptor NKp46 Regulates Graft-versus-Host Disease
Published in Cell reports (Cambridge) (26-06-2014)“…Hematopoietic stem cell transplantation (HSCT) is often the only curative treatment for a wide variety of hematologic malignancies. Donor selection in these…”
Get full text
Journal Article -
9
HSV-2 specifically down regulates HLA-C expression to render HSV-2-infected DCs susceptible to NK cell killing
Published in PLoS pathogens (01-03-2013)“…Both NK cells and CTLs kill virus-infected and tumor cells. However, the ways by which these killer cells recognize the infected or the tumorigenic cells are…”
Get full text
Journal Article -
10
Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D
Published in Nature immunology (01-09-2008)“…The mechanisms controlling expression of the stress-induced NKG2D ligands MICA and MICB are not fully understood. Mandelboim and colleagues suggest that…”
Get full text
Journal Article -
11
NK p46 regulates allergic responses
Published in European journal of immunology (01-11-2013)“…Natural killer ( NK ) cells are cytotoxic cells that are able to rapidly kill viruses, tumor cells, parasites, bacteria, and even cells considered “self”. The…”
Get full text
Journal Article -
12
HSV-2 Specifically Down Regulates HLA-C Expression to Render HSV-2-Infected DCs Susceptible to NK Cell Killing: e1003226
Published in PLoS pathogens (01-03-2013)“…Both NK cells and CTLs kill virus-infected and tumor cells. However, the ways by which these killer cells recognize the infected or the tumorigenic cells are…”
Get full text
Journal Article -
13
The Association of MHC Class I Proteins with the 2B4 Receptor Inhibits Self-Killing of Human NK Cells
Published in The Journal of immunology (1950) (15-03-2010)“…The killing activity of NK cells is carried out by several activating NK receptors, which includes NKp46, NKp44, NKp30, NKp80, NKG2D, and 2B4. The ligands of…”
Get full text
Journal Article -
14
NK cytotoxicity mediated by CD16 but not by NKp30 is functional in Griscelli syndrome
Published in Blood (15-05-2007)“…Griscelli syndrome (GS) type 2 is an autosomal recessive disorder represented by pigment dilution and impaired cytotoxic T lymphocyte (CTL) activity. NK…”
Get full text
Journal Article