Search Results - "Elbaz, Alexis"

Obesity trajectories and risk of dementia: 28 years of follow-up in the Whitehall II Study by Singh-Manoux, Archana, Dugravot, Aline, Shipley, Martin, Brunner, Eric J., Elbaz, Alexis, Sabia, Séverine, Kivimaki, Mika

“…We examined whether obesity at ages 50, 60, and 70 years is associated with subsequent dementia. Changes in body mass index (BMI) for more than 28 years before…”
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Physical activity, cognitive decline, and risk of dementia: 28 year follow-up of Whitehall II cohort study by Sabia, Séverine, Dugravot, Aline, Dartigues, Jean-François, Abell, Jessica, Elbaz, Alexis, Kivimäki, Mika, Singh-Manoux, Archana

“…AbstractObjectiveTo test the hypotheses that physical activity in midlife is not associated with a reduced risk of dementia and that the preclinical phase of…”
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Atrial fibrillation as a risk factor for cognitive decline and dementia by Singh-Manoux, Archana, Fayosse, Aurore, Sabia, Séverine, Canonico, Marianne, Bobak, Martin, Elbaz, Alexis, Kivimäki, Mika, Dugravot, Aline

“…To assess whether AF is a risk factor for cognitive dysfunction we used prospective data on AF, repeat cognitive scores, and dementia incidence in adults…”
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Interleukin-6 and C-reactive protein as predictors of cognitive decline in late midlife by Singh-Manoux, Archana, Dugravot, Aline, Brunner, Eric, Kumari, Meena, Shipley, Martin, Elbaz, Alexis, Kivimaki, Mika

“…OBJECTIVE:Peripheral inflammatory markers are elevated in patients with dementia. In order to assess their etiologic role, we examined whether interleukin-6…”
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Decline in Fast Gait Speed as a Predictor of Disability in Older Adults by Artaud, Fanny, Singh-Manoux, Archana, Dugravot, Aline, Tzourio, Christophe, Elbaz, Alexis

“…Objectives To determine whether fast gait speed at study baseline and change in gait speed had independent associations with disability onset. Design Cohort…”
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Projections of prevalence, lifetime risk, and life expectancy of Parkinson's disease (2010‐2030) in France by Wanneveich, Mathilde, Moisan, Frédéric, Jacqmin‐Gadda, Hélène, Elbaz, Alexis, Joly, Pierre

“…ABSTRACT Background: Previous studies on the number of Parkinson's disease (PD) patients in the future based on projections of population size underestimated…”
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Alcohol consumption and cognitive decline in early old age by Sabia, Séverine, Elbaz, Alexis, Britton, Annie, Bell, Steven, Dugravot, Aline, Shipley, Martin, Kivimaki, Mika, Singh-Manoux, Archana

“…OBJECTIVE:To examine the association between alcohol consumption in midlife and subsequent cognitive decline. METHODS:Data are from 5,054 men and 2,099 women…”
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Prevalence and incidence of young onset dementia and associations with comorbidities: A study of data from the French national health data system by Carcaillon-Bentata, Laure, Quintin, Cécile, Boussac-Zarebska, Marjorie, Elbaz, Alexis

“…Background Dementia onset in those aged <65 years (young onset dementia, YOD) has dramatic individual and societal consequences. In the context of population…”
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Midlife type 2 diabetes and poor glycaemic control as risk factors for cognitive decline in early old age: a post-hoc analysis of the Whitehall II cohort study by Tuligenga, Richard H, MD, Dugravot, Aline, MSc, Tabák, Adam G, MD, Elbaz, Alexis, MD, Brunner, Eric J, PhD, Kivimäki, Mika, PhD, Singh-Manoux, Archana, Dr

“…Summary Background Type 2 diabetes increases the risk for dementia, but whether it affects cognition before old age is unclear. We investigated whether…”
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RISK OF CARDIOVASCULAR DISEASE MORBIDITY AND MORTALITY IN FRAIL AND PRE-FRAIL OLDER ADULTS: RESULTS FROM A META-ANALYSIS AND EXPLORATORY META-REGRESSION ANALYSIS by Veronese, Nicola, Cereda, Emanuele, Stubbs, Brendon, Solmi, Marco, Luchini, Claudio, Manzato, Enzo, Sergi, Giuseppe, Manu, Peter, Harris, Tamara, Fontana, Luigi, Strandberg, Timo, Amieva, Helene, Dumurgier, Julien, Elbaz, Alexis, Tzourio, Christophe, Eicholzer, Monika, Rohrmann, Sabine, Moretti, Claudio, D’Ascenzo, Fabrizio, Quadri, Giorgio, Polidoro, Alessandro, Lourenço, Roberto Alves, Moreira, Virgilio Garcia, Sanchis, Juan, Scotti, Valeria, Maggi, Stefania, Correll, Christoph U

“…Highlights • If frailty is a potential cardiovascular risk factor is poorly known. • In our work frailty was associated with higher prevalence and incidence of…”
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Contribution of cognitive performance and cognitive decline to associations between socioeconomic factors and dementia: A cohort study by Rusmaully, Jennifer, Dugravot, Aline, Moatti, Jean-Paul, Marmot, Michael G, Elbaz, Alexis, Kivimaki, Mika, Sabia, Séverine, Singh-Manoux, Archana

“…Socioeconomic disadvantage is a risk factor for dementia, but longitudinal studies suggest that it does not affect the rate of cognitive decline. Our objective…”
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Professional exposure to pesticides and Parkinson disease by Elbaz, Alexis, Clavel, Jacqueline, Rathouz, Paul J., Moisan, Frédéric, Galanaud, Jean-Philippe, Delemotte, Bernard, Alpérovitch, Annick, Tzourio, Christophe

“…Objective We studied the relation between Parkinson disease (PD) and professional exposure to pesticides in a community‐based case‐control study conducted in a…”
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Subjective cognitive complaints and mortality: Does the type of complaint matter? by Singh-Manoux, Archana, Dugravot, Aline, Ankri, Joel, Nabi, Hermann, Berr, Claudine, Goldberg, Marcel, Zins, Marie, Kivimaki, Mika, Elbaz, Alexis

“…Abstract Middle-aged subjects report subjective cognitive complaints (SSCs) but whether these are meaningfully related to health remains unknown. We examined…”
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The gait speed advantage of taller stature is lost with age by Elbaz, Alexis, Artaud, Fanny, Dugravot, Aline, Tzourio, Christophe, Singh-Manoux, Archana

“…Taller individuals walk faster but it is unknown whether this advantage persists at older ages. We examined the cross-sectional/longitudinal associations of…”
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Examining the Reserve Hypothesis in Parkinson's Disease: A Longitudinal Study by Lee, Pei‐Chen, Artaud, Fanny, Cormier‐Dequaire, Florence, Rascol, Olivier, Durif, Franck, Derkinderen, Pascal, Marques, Ana‐Raquel, Bourdain, Frédéric, Brandel, Jean‐Philippe, Pico, Fernando, Lacomblez, Lucette, Bonnet, Cecilia, Brefel‐Courbon, Christine, Ory‐Magne, Fabienne, Grabli, David, Klebe, Stephan, Mangone, Graziella, You, Hana, Mesnage, Valérie, Brice, Alexis, Vidailhet, Marie, Corvol, Jean‐Christophe, Elbaz, Alexis

“…Background Whether reserve plays a role in Parkinson's disease (PD) patients has received less attention than in dementia and has been mainly examined in…”
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Association between Parkinson's disease and the HLA-DRB1 locus by Ahmed, Ismaïl, Tamouza, Ryad, Delord, Marc, Krishnamoorthy, Rajagopal, Tzourio, Christophe, Mulot, Claire, Nacfer, Magali, Lambert, Jean-Charles, Beaune, Philippe, Laurent-Puig, Pierre, Loriot, Marie-Anne, Charron, Dominique, Elbaz, Alexis

“…Two genome‐wide association studies (GWASs) recently highlighted the HLA‐DRA and HLA‐DRB5 genes as associated with Parkinson disease (PD). However, because…”
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Pooled analysis of the HLA‐DRB1 by smoking interaction in Parkinson disease by Chuang, Yu‐Hsuan, Lee, Pei‐Chen, Vlaar, Tim, Mulot, Claire, Loriot, Marie‐Anne, Hansen, Johnni, Lill, Christina M., Ritz, Beate, Elbaz, Alexis

“…Objective Inflammatory response plays an important role in Parkinson disease (PD). Previous studies have reported an association between human leukocyte…”
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Pooled analysis of iron-related genes in Parkinson's disease: Association with transferrin by Rhodes, Shannon L, Buchanan, Daniel D, Ahmed, Ismaïl, Taylor, Kent D, Loriot, Marie-Anne, Sinsheimer, Janet S, Bronstein, Jeff M, Elbaz, Alexis, Mellick, George D, Rotter, Jerome I, Ritz, Beate

“…Abstract Pathologic features of Parkinson's disease (PD) include death of dopaminergic neurons in the substantia nigra, presence of α-synuclein containing Lewy…”
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Body mass index trajectories and functional decline in older adults: Three-City Dijon cohort study by Artaud, Fanny, Singh-Manoux, Archana, Dugravot, Aline, Tavernier, Béatrice, Tzourio, Christophe, Elbaz, Alexis

“…Obesity, whose prevalence is increasing, is associated with poor functional status at older ages. However, much of this evidence is cross-sectional with little…”
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Bidirectional Relation Between Parkinson's Disease and Glioblastoma Multiforme by Mencke, Pauline, Hanss, Zoé, Boussaad, Ibrahim, Sugier, Pierre-Emmanuel, Elbaz, Alexis, Krüger, Rejko

“…Cancer and Parkinson's disease (PD) define two disease entities that include opposite concepts. Indeed, the involved mechanisms are at different ends of a…”
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