Search Results - "Elbayaa, Rasha Y."
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1
Synthesis and anticancer activity of novel benzimidazole and benzothiazole derivatives against HepG2 liver cancer cells
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-03-2012)“…Most of cancer chemotherapeutics and chemopreventives exert their effects by triggering apoptotic cell death. In this study, novel benzimidazole and…”
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2
Design, synthesis and molecular docking study of some substituted 4,5- dihydro-2H-indazole derivatives as potential anti-inflammatory agents
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-08-2013)“…A new series of 4,5-dihydro-2H-indazoles was synthesized and evaluated for anti-inflammatory activity using formalin-induced paw edema and turpentine…”
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3
Design, synthesis, antibacterial evaluation and molecular docking studies of some new quinoxaline derivatives targeting dihyropteroate synthase enzyme
Published in Bioorganic chemistry (01-02-2018)“…Rational design of the target antibacterial DHPS inhibitors. [Display omitted] Development of new antimicrobial agents is a good solution to overcome…”
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4
Computer-aided design, synthesis, and biological evaluation of 5- substituted aminomethylenepyrimidine-2,4,6-triones as H₁ antihistaminic agents (Part2)
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (2014)“…As a part of a research project pertaining to the synthesis of novel candidates as nonsedating, nonclassic H₁ histaminergic (H₁) blockers with low toxicity…”
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5
Novel quinuclidinone derivatives induced apoptosis in human breast cancer via targeting p53
Published in Bioorganic chemistry (01-06-2017)“…The present work describes the design and synthesis of novel series of five quinuclidinone derivatives (2a-2e). Their anticancer activities were investigated…”
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6
Synthesis of some new amide-linked bipyrazoles and their evaluation as anti-inflammatory and analgesic agents
Published in Journal of enzyme inhibition and medicinal chemistry (01-11-2016)“…Four series of new bipyrazoles comprising the N-phenylpyrazole scaffold linked to polysubstituted pyrazoles or to antipyrine moiety through different amide…”
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7
Synthesis of pyrazolo-1,2,4-triazolo[4,3-a]quinoxalines as antimicrobial agents with potential inhibition of DHPS enzyme
Published in Future medicinal chemistry (01-09-2018)“…The development of a new class of antimicrobial agents is the optimal lifeline to scrap the escalating jeopardy of drug resistance. This study aims to design…”
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8
Novel thiosemicarbazides induced apoptosis in human MCF-7 breast cancer cells via JNK signaling
Published in Journal of enzyme inhibition and medicinal chemistry (03-09-2015)“…In this study, novel thiosemicarbazides and 1,3,4-oxadiazoles were synthesized and evaluated for their anticancer effects on human MCF-7 breast cancer cell…”
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9
Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells
Published in Journal of enzyme inhibition and medicinal chemistry (01-12-2016)“…Novel 1,5-diphenyl-6-substituted-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones were synthesized and characterized. All compounds were screened for their…”
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10
Synthesis of pyrazolo-1,2,4-triazolo[4,3
Published in Future medicinal chemistry (01-08-2018)“…The development of a new class of antimicrobial agents is the optimal lifeline to scrap the escalating jeopardy of drug resistance. This study aims to design…”
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