Search Results - "Elbadry, Mahmoud I"
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Coagulation parameters abnormalities and their relation to clinical outcomes in hospitalized and severe COVID-19 patients: prospective study
Published in Scientific reports (01-08-2022)“…There has been growing attention toward the predictive value of the coagulation parameters abnormalities in COVID-19. The aim of the study was to…”
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Comparison of Successful Myocardial Reperfusion and Adverse Events in Patients With ST-Elevation Myocardial Infarction Who Underwent Rescue Percutaneous Coronary Intervention After Failed Fibrinolytic Therapy With Versus Without Manual Coronary Thrombus Aspiration
Published in The American journal of cardiology (15-10-2015)“…It has been unclear the impact of manual thrombus aspiration (TA) on procedural outcomes in patients with ST-elevation myocardial infarction (STEMI) who…”
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Induced pluripotent stem cell technology: A window for studying the pathogenesis of acquired aplastic anemia and possible applications
Published in Experimental hematology (01-05-2017)“…Recent progress in human induced pluripotent stem cells (iPSCs) has opened the door to a better understanding of the biology of human diseases, especially rare…”
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Clonal hematopoiesis by SLIT1-mutated hematopoietic stem cells due to a breakdown of the autocrine loop involving Slit1 in acquired aplastic anemia
Published in Leukemia (01-11-2019)Get full text
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Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia
Published in Haematologica (Roma) (01-10-2019)Get full text
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Hematopoiesis by iPSC-derived hematopoietic stem cells of aplastic anemia that escape cytotoxic T-cell attack
Published in Blood advances (27-02-2018)“…Hematopoietic stem cells (HSCs) that lack HLA-class I alleles as a result of copy-number neutral loss of heterozygosity of the short arm of chromosome 6…”
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Selective immunoglobulin M deficiency in an adult with miliary tuberculosis: A clinically interesting coexistence. A case report and review of the literature
Published in International journal of mycobacteriology (01-03-2016)“…Abstract Selective immunoglobulin M (SIgM) deficiency is a rare form of dysgammaglobulinemia. Here we are reporting a 31 year old man with multiple cervical…”
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Association between rs1761667 polymorphism of CD36 gene and risk of coronary atherosclerosis in Egyptian population
Published in Cardiovascular diagnosis and therapy (01-04-2016)Get full text
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Unusual pattern of thrombotic events in young adult non‐critically ill patients with COVID‐19 may result from an undiagnosed inherited and acquired form of thrombophilia
Published in British journal of haematology (01-02-2022)“…Summary In 145 previously healthy non‐critically ill young adults, coronavirus disease 2019 (COVID‐19)‐related symptoms, risk factors for thrombosis,…”
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Disease modeling of bone marrow failure syndromes using iPSC-derived hematopoietic stem progenitor cells
Published in Experimental hematology (01-03-2019)“…•Induced pluripotent stem cells (iPSCs) can be generated from patients with bone marrow failure syndromes (BMFSs).•Patient-derived iPSCs can generate…”
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CXC chemokine ligand 13 and galectin-9 plasma levels collaboratively provide prediction of disease activity and progression-free survival in chronic lymphocytic leukemia
Published in Annals of hematology (01-03-2024)“…The clinical outcome of lymphocytic leukemia (CLL) is quite heterogeneous. The purpose of this observational study was to investigate the clinical merit of…”
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The GPI-anchored protein CD109 protects hematopoietic progenitor cells from undergoing erythroid differentiation induced by TGF-β
Published in Leukemia (01-03-2022)“…Although a glycosylphosphatidylinositol-anchored protein (GPI-AP) CD109 serves as a TGF-β co-receptor and inhibits TGF-β signaling in keratinocytes, the role…”
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Acute human parvovirus B19 infection triggers immune‐mediated transient bone marrow failure syndrome, extreme direct hyperbilirubinaemia and acute hepatitis in patients with hereditary haemolytic anaemias: multicentre prospective pathophysiological study
Published in British journal of haematology (01-05-2021)“…Summary A total of 244 patients with hereditary haemolytic anaemias (HHA) were screened for acute symptomatic human parvovirus B19 infection (HPV‐B19) in a…”
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A rare homozygous variant in TERT gene causing variable bone marrow failure, fragility fractures, rib anomalies and extremely short telomere lengths with high serum IgE
Published in British journal of haematology (01-03-2024)“…By whole exome sequencing, we identified a homozygous c.2086 C→T (p.R696C) TERT mutation in patients who present with a spectrum of variable bone marrow…”
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An altered gut microbiota may trigger autoimmune-mediated acquired bone marrow failure syndromes
Published in Clinical immunology (Orlando, Fla.) (01-10-2016)Get full text
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The simultaneous inhibition of the mTOR and MAPK pathways with Gnetin-C induces apoptosis in acute myeloid leukemia
Published in Cancer letters (01-08-2017)“…Abstract Acute myelogenous leukemia (AML) is a clinically heterogeneous disease that is frequently associated with relapse and a poor prognosis. Among the…”
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A functional polymorphism in the NKG2D gene modulates NK-cell cytotoxicity and is associated with susceptibility to Human Papilloma Virus-related cancers
Published in Scientific reports (20-12-2016)“…Human papillomavirus (HPV) is the most common sexually transmitted agent worldwide and is etiologically linked to several cancers, including cervical and…”
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Hematological, Biochemical Properties, and Clinical Correlates of Hemoglobin S Variant Disorder: A New Insight Into Sickle Cell Trait
Published in Journal of hematology (01-06-2022)Get full text
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Venous Thromboembolism Risk Assessment among Beta-thalassemia Patients
Published in Journal of Applied Hematology (01-07-2023)“…BACKGROUND: Thromboembolic (TE) disorders are among the most common complications of beta-thalassemia. We designed this cross-sectional study to investigate…”
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Resistance of KIR Ligand-Missing Leukocytes to NK Cells In Vivo in Patients with Acquired Aplastic Anemia
Published in ImmunoHorizons (17-07-2020)“…The loss of killer cell Ig-like receptor ligands (KIR-Ls) due to the copy number-neutral loss of heterozygosity of chromosome 6p (6pLOH) in leukocytes of…”
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