Search Results - "Elashoff, David A."

Dynamic Changes in Intracellular ROS Levels Regulate Airway Basal Stem Cell Homeostasis through Nrf2-Dependent Notch Signaling by Paul, Manash K., Bisht, Bharti, Darmawan, Daphne O., Chiou, Richard, Ha, Vi L., Wallace, William D., Chon, Andrew T., Hegab, Ahmed E., Grogan, Tristan, Elashoff, David A., Alva-Ornelas, Jackelyn A., Gomperts, Brigitte N.

“…Airways are exposed to myriad environmental and damaging agents such as reactive oxygen species (ROS), which also have physiological roles as signaling…”
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Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses by Gunawardana, Hasitha, Romero, Tahmineh, Yao, Ning, Heidt, Sebastiaan, Mulder, Arend, Elashoff, David A., Valenzuela, Nicole M.

“…Endothelial cells (EC) coordinate vascular homeostasis and inflammation. In organ transplantation, EC are a direct alloimmune target. We posited that tissue…”
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Differential microRNA expression in human placentas of term intra-uterine growth restriction that regulates target genes mediating angiogenesis and amino acid transport by Thamotharan, Shanthie, Chu, Alison, Kempf, Katie, Janzen, Carla, Grogan, Tristan, Elashoff, David A, Devaskar, Sherin U

“…Placental insufficiency leading to intrauterine growth restriction (IUGR) demonstrates perturbed gene expression affecting placental angiogenesis and nutrient…”
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Joint-specific assessment of swelling and power Doppler in obese rheumatoid arthritis patients by Bauer, Erin M, Ben-Artzi, Ami, Duffy, Erin L, Elashoff, David A, Vangala, Sitaram S, Fitzgerald, John, Ranganath, Veena K

“…Clinical swollen joint examination of the obese rheumatoid arthritis (RA) patient can be difficult. Musculoskeletal Ultrasound (MSUS) has higher sensitivity…”
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Low-Dose Intravenous Soybean Oil Emulsion for Prevention of Cholestasis in Preterm Neonates by Levit, Orly L., Calkins, Kara L., Gibson, L. Caroline, Kelley-Quon, Lorraine, Robinson, Daniel T., Elashoff, David A., Grogan, Tristan R., Li, Ning, Bizzarro, Matthew J., Ehrenkranz, Richard A.

“…Background: Premature infants depend on intravenous fat emulsions to supply essential fatty acids and calories. The dose of soybean-based intravenous fat…”
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Snail Promotes CXCR2 Ligand–Dependent Tumor Progression in Non–Small Cell Lung Carcinoma by Yanagawa, Jane, Walser, Tonya C, Zhu, Li X, Hong, Longsheng, Fishbein, Michael C, Mah, Vei, Chia, David, Goodglick, Lee, Elashoff, David A, Luo, Jie, Magyar, Clara E, Dohadwala, Mariam, Lee, Jay M, St John, Maie A, Strieter, Robert M, Sharma, Sherven, Dubinett, Steven M

“…Purpose: As a transcriptional repressor of E-cadherin, Snail has predominantly been associated with epithelial-mesenchymal transition, invasion, and…”
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Distinctive profile of monomeric and polymeric anti-SSA/Ro52 immunoglobulin A1 isoforms in saliva of patients with primary Sjögren’s syndrome and Sicca by Chiang, Samantha, Grogan, Tristan, Kamounah, Sarah, Wei, Fang, Tayob, Nabihah, Kim, Ju Yeon, Kyun Park, Jin, Akin, David, Elashoff, David A, Pedersen, Anne Marie Lynge, Song, Yeong Wook, Wong, David T W, Chia, David

“…ObjectivePrimary Sjögren’s syndrome (pSS) is the second most common chronic autoimmune connective tissue disease. Autoantibodies, immunoglobulin (IgG)…”
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Proinflammatory Mediators Upregulate Snail in Head and Neck Squamous Cell Carcinoma by St John, Maie A, Dohadwala, Mariam, Luo, Jie, Wang, Guanyu, Lee, Gina, Shih, Hubert, Heinrich, Eileen, Krysan, Kostantyn, Walser, Tonya, Hazra, Saswati, Zhu, Li, Lai, Chi, Abemayor, Elliot, Fishbein, Michael, Elashoff, David A, Sharma, Sherven, Dubinett, Steven M

“…Purpose: Inflammatory cytokines have been implicated in the progression of head and neck squamous cell carcinoma (HNSCC). Herein we investigate the mechanisms…”
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Detection of Circulating Tumor Cells in Early-Stage Breast Cancer Metastasis to Axillary Lymph Nodes by NAKAGAWA, Taku, MARTINEZ, Steve R, HOON, Dave S. B, GOTO, Yasufumi, KOYANAGI, Kazuo, KITAGO, Minoru, SHINGAI, Tatsushi, ELASHOFF, David A, XING YE, SINGER, Frederick R, GIULIANO, Armando E

“…Purpose: Clinical and pathologic prognostic factors do not always accurately predict disease outcome. Patients with early-stage breast cancer may harbor…”
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Hypomethylation of LINE-1 in primary tumor has poor prognosis in young breast cancer patients: a retrospective cohort study by van Hoesel, Anneke Q., van de Velde, Cornelis J. H., Kuppen, Peter J. K., Liefers, Gerrit Jan, Putter, Hein, Sato, Yusuke, Elashoff, David A., Turner, Roderick R., Shamonki, Jaime M., de Kruijf, Esther M., van Nes, Johanna G. H., Giuliano, Armando E., Hoon, Dave S. B.

“…Long interspersed element 1 (LINE-1), a non-coding genomic repeat sequence, methylation status can influence tumor progression. In this study, the clinical…”
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A novel classification system for perineural invasion in noncutaneous head and neck squamous cell carcinoma: histologic subcategories and patient outcomes by Miller, Mia E., MD, Palla, Beth, MD, Chen, Qiaolin, PhD, Elashoff, David A., MD, PhD, Abemayor, Elliot, MD, PhD, St. John, Maie A., MD, PhD, Lai, Chi K., MD

“…Abstract Objective The aims of this study were to define a novel classification system of tumor perineural invasion (PNI) with respect to tumor/nerve…”
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Nodal Stage Classification for Breast Carcinoma: Improving Interobserver Reproducibility Through Standardized Histologic Criteria and Image-Based Training by TURNER, Roderick R, WEAVER, Donald L, SCHNITT, Stuart J, GIULIANO, Armando E, CSERNI, Gabor, LESTER, Susan C, HIRSCH, Karen, ELASHOFF, David A, FITZGIBBONS, Patrick L, VIALE, Giuseppe, MAZZAROL, Giovanni, IBARRA, Julio A

“…Reliable pathologic stage classification of axillary lymph nodes is an important determinant of prognosis and therapeutic decision making for patients with…”
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Adenoid cystic carcinoma of the airway: a 30-year review at one institution by Calzada, Audrey P., MD, Miller, Mia, MD, Lai, Chi K., MD, Elashoff, David A., PhD, Abemayor, Elliot, MD, PhD, St. John, Maie A., MD, PhD

“…Abstract Purpose The purpose of the study was to evaluate the treatment results of adenoid cystic carcinoma (ACC) of the airway at a single institution during…”
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CD38 is methylated in prostate cancer and regulates extracellular NAD by Mottahedeh, Jack, Haffner, Michael C, Grogan, Tristan R, Hashimoto, Takao, Crowell, Preston D, Beltran, Himisha, Sboner, Andrea, Bareja, Rohan, Esopi, David, Isaacs, William B, Yegnasubramanian, Srinivasan, Rettig, Matthew B, Elashoff, David A, Platz, Elizabeth A, De Marzo, Angelo M, Teitell, Michael A, Goldstein, Andrew S

“…Cancer cell metabolism requires sustained pools of intracellular nicotinamide adenine dinucleotide (NAD ) which is maintained by a balance of NAD hydrolase…”
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Ultrasound detects synovitis in replaced and other surgically operated joints in rheumatoid arthritis patients by Choate, Evan A, Kaeley, Gurjit S, Brook, Jenny, Altman, Roy D, FitzGerald, John D, Floegel-Shetty, Astrid R, Elashoff, David A, Ranganath, Veena K

“…Joint replacements continue to occur during a rheumatoid arthritis (RA) patient's lifetime despite significant advances in available treatment options. The…”
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Cholesterol-lowering effects of a proprietary Chinese red-yeast-rice dietary supplement by HEBER, D, YIP, I, ASHLEY, J. M, ELASHOFF, D. A, ELASHOFF, R. M, GO, V. L. W

“…We examined the cholesterol-lowering effects of a proprietary Chinese red-yeast-rice supplement in an American population consuming a diet similar to the…”
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PD-1 blockade induces responses by inhibiting adaptive immune resistance by Tumeh, Paul C., Harview, Christina L., Yearley, Jennifer H., Shintaku, I. Peter, Taylor, Emma J. M., Robert, Lidia, Chmielowski, Bartosz, Spasic, Marko, Henry, Gina, Ciobanu, Voicu, West, Alisha N., Carmona, Manuel, Kivork, Christine, Seja, Elizabeth, Cherry, Grace, Gutierrez, Antonio J., Grogan, Tristan R., Mateus, Christine, Tomasic, Gorana, Glaspy, John A., Emerson, Ryan O., Robins, Harlan, Pierce, Robert H., Elashoff, David A., Robert, Caroline, Ribas, Antoni

“…The dynamics of T-cell responses are investigated in tumour tissue from patients with advanced melanoma who were treated with a PD-1-blocking monoclonal…”
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The role of ZEB1 in the inflammation-induced promotion of EMT in HNSCC by Dohadwala, Mariam, Wang, Guanyu, Heinrich, Eileen, Luo, Jie, Lau, Ontario, Shih, Hubert, Munaim, Qahera, Lee, Gina, Hong, Longsheng, Lai, Chi, Abemayor, Elliot, Fishbein, Michael C., Elashoff, David A., Dubinett, Steven M., St. John, Maie A.

“…To determine the role of ZEB1 in the inflammation-induced promotion of the epithelial-mesenchymal transition (EMT) in head and neck squamous cell carcinoma…”
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Distinct components of alert fatigue in physicians' responses to a noninterruptive clinical decision support alert by Murad, Douglas A, Tsugawa, Yusuke, Elashoff, David A, Baldwin, Kevin M, Bell, Douglas S

“…Clinical decision support (CDS) alerts may improve health care quality but "alert fatigue" can reduce provider responsiveness. We analyzed how the introduction…”
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Phase I Trial of Intratumoral Injection of CCL21 Gene-Modified Dendritic Cells in Lung Cancer Elicits Tumor-Specific Immune Responses and CD8 + T-cell Infiltration by Lee, Jay M, Lee, Mi-Heon, Garon, Edward, Goldman, Jonathan W, Salehi-Rad, Ramin, Baratelli, Felicita E, Schaue, Dörthe, Wang, Gerald, Rosen, Fran, Yanagawa, Jane, Walser, Tonya C, Lin, Ying, Park, Stacy J, Adams, Sharon, Marincola, Francesco M, Tumeh, Paul C, Abtin, Fereidoun, Suh, Robert, Reckamp, Karen L, Lee, Gina, Wallace, William D, Lee, Sarah, Zeng, Gang, Elashoff, David A, Sharma, Sherven, Dubinett, Steven M

“…A phase I study was conducted to determine safety, clinical efficacy, and antitumor immune responses in patients with advanced non-small cell lung carcinoma…”
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