Search Results - "ElMeshad, Aliaa Nabil"
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Nanocarrier Systems in Taste Masking
Published in Scientia pharmaceutica (01-01-2022)“…Taste is the most crucial organoleptic parameter affecting patient compliance in the case of drugs with poor palatability. Taste masking is a major challenge…”
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Hybrid chitosan-lipid nanoparticles of green tea extract as natural anti-cellulite agent with superior in vivo potency: full synthesis and analysis
Published in Drug delivery (01-01-2021)“…The aim of this work is to exploit the advantages of chitosan (CS) as a nanocarrier for delivery of anti-cellulite drug, green tea extract (GTE), into…”
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PLGA/PEG Nanoparticles Loaded with Cyclodextrin- Peganum harmala Alkaloid Complex and Ascorbic Acid with Promising Antimicrobial Activities
Published in Pharmaceutics (07-01-2022)“…Antimicrobial drugs face numerous challenges, including drug resistance, systemic toxic effects, and poor bioavailability. To date, treatment choices are…”
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Comparative Study on the Effects of Some Polyoxyethylene Alkyl Ether and Sorbitan Fatty Acid Ester Surfactants on the Performance of Transdermal Carvedilol Proniosomal Gel Using Experimental Design
Published in AAPS PharmSciTech (01-12-2010)“…The aim of this work was to investigate the effects of formulation variables on development of carvedilol (CAR) proniosomal gel formulations as potential…”
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5
Microemulsion loaded hydrogel as a promising vehicle for dermal delivery of the antifungal sertaconazole: design, optimization and ex vivo evaluation
Published in Drug development and industrial pharmacy (03-08-2017)“…The purpose of the present study was to develop and optimize sertaconazole microemulsion-loaded hydrogel (STZ ME G) to enhance the dermal delivery and skin…”
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6
Investigating the root cause of N-nitrosodimethylamine formation in metformin pharmaceutical products
Published in Expert opinion on drug safety (03-07-2021)“…FDA limited N-nitrosodimethylamine (NDMA) - a carcinogenic impurity formed during metformin (MET) tablets manufacturing - level to 96 ng/day; a step which led…”
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Impact of Reverse Micelle Loaded Lipid Nanocapsules on the Delivery of Gallic Acid into Activated Hepatic Stellate Cells: A Promising Therapeutic Approach for Hepatic Fibrosis
Published in Pharmaceutical research (01-09-2020)“…Purpose Gallic acid (GA) is a polyphenolic compound with proven efficacy against hepatic fibrosis in experimental animals. However, it suffers from poor…”
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Drug delivery systems integrated with conventional and advanced treatment approaches toward cellulite reduction
Published in Journal of drug delivery science and technology (01-12-2020)“…Cellulite is a multifactorial condition induced by topographic alteration of skin giving rise to ‘orange peel’ appearance. It is a universal aesthetic problem…”
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A pharmaceutical study on chlorzoxazone orodispersible tablets: formulation, in-vitro and in-vivo evaluation
Published in Drug delivery (12-10-2016)“…Muscle spasm needs prompt relief of symptoms. Chlorzoxazone is a centrally muscle relaxant. The aim of this study was to prepare chlorzoxazone orodispersible…”
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Comparative study of different approaches for preparation of chlorzoxazone orodispersible tablets
Published in Drug development and industrial pharmacy (04-05-2017)“…Context: Muscle spasm is a painful involuntary contraction of muscles, which causes involuntary movement and distortion. Chlorzoxazone is a centrally acting…”
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Transdermal Delivery of an Anti-Cancer Drug via W/O Emulsions Based on Alkyl Polyglycosides and Lecithin: Design, Characterization, and In Vivo Evaluation of the Possible Irritation Potential in Rats
Published in AAPS PharmSciTech (01-03-2011)“…The purpose of this work was to develop w/o emulsions that could be safely used to promote transdermal delivery of 5-fluorouracil (5-FU). Two pseudo-ternary…”
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Gastroretentive Microsponge as a Promising Tool for Prolonging the Release of Mitiglinide Calcium in Type-2 Diabetes Mellitus: Optimization and Pharmacokinetics Study
Published in AAPS PharmSciTech (01-08-2018)“…Diabetes mellitus is one of the leading causes of death due to the persistent hyperglycemia that leads to potential complications. Lack of patients’ adherence…”
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13
Investigating the root cause of N-nitrosodimethylamine formation in metformin pharmaceutical products
Published in Expert opinion on drug safety (01-02-2022)Get more information
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14
Correction to: Impact of Reverse Micelle Loaded Lipid Nanocapsules on the Delivery of Gallic Acid into Activated Hepatic Stellate Cells: A Promising Therapeutic Approach for Hepatic Fibrosis
Published in Pharmaceutical research (01-11-2020)“…This erratum is to correct the name of the moiety responsible for the negativity of Lipoid S75…”
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Synthesis, Characterization and Biocompatibility of N-palmitoyl L-alanine-based Organogels as Sustained Implants of Granisetron and Evaluation of thier Antiemetic Effect
Published in Pharmaceutical research (01-08-2018)“…To assess the gelation power of N-palmitoyl L-alanine derivatives in injectable oils and to use the best chosen organogel as parenteral implant of granisetron…”
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Targeted photodynamic-induced singlet oxygen production by peptide-conjugated biodegradable nanoparticles for treatment of skin melanoma
Published in Photodiagnosis and photodynamic therapy (01-09-2018)“…Targeted photodynamic-induced singlet oxygen production by peptide-conjugated biodegradable nanoparticles for treatment of skin melanoma. [Display omitted]…”
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Zein/Phospholipid Composite Nanoparticles for Successful Delivery of Gallic Acid into aHSCs: Influence of Size, Surface Charge, and Vitamin A Coupling
Published in International journal of nanomedicine (01-01-2020)“…Zein/phospholipid composite nanoparticles (CNPs) were developed as a delivery platform for gallic acid (GA), a polyphenolic compound with reported preclinical…”
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18
A pharmaceutical study on lornoxicam fast disintegrating tablets: formulation and in vitro and in vivo evaluation
Published in Drug delivery and translational research (01-06-2017)“…Lornoxicam is an anti-inflammatory drug used to relieve rheumatoid arthritis pain, but the low water solubility and bitter taste of the drug present challenges…”
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Cromolyn chitosan nanoparticles as a novel protective approach for colorectal cancer
Published in Chemico-biological interactions (25-09-2017)“…Colorectal cancer is the third most common cancer in the world. Cromolyn is a mast cell stabilizer and was proposed as an anticancer agent; however its high…”
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Synthesis, Characterization and Biocompatibility of N-palmitoyl L-alanine-based Organogels as Sustained Implants of Granisetron and Evaluation of their Antiemetic Effect
Published in Pharmaceutical research (01-08-2018)“…Purpose To assess the gelation power of N -palmitoyl L-alanine derivatives in injectable oils and to use the best chosen organogel as parenteral implant of…”
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