Search Results - "ElHaddad, Alaa"
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High risk Langerhans cell histiocytosis in children: the role of salvage in improving the outcome. A single center experience
Published in Orphanet journal of rare diseases (24-06-2024)“…In pediatric multi-system high risk organs (RO +) Langerhans cell histiocytosis (LCH), failing 1st line treatment has the highest mortality. We aim to present…”
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Pediatric pulmonary multisystem langerhans cell histiocytosis: does lung lesion severity affect the outcome?
Published in Orphanet journal of rare diseases (17-11-2023)“…Abstract Background The pediatric pulmonary multisystem Langerhans cell histiocytosis (PPM LCH) is associated with either low risk or high risk organ(s). The…”
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Patterns of expression of VEGFR2, PDGFRs and c-Kit in pediatric patients with high grade non-rhabdomyosarcoma soft tissue sarcoma
Published in Frontiers in oncology (29-10-2024)“…Introduction Activated vascular endothelial growth factor receptors (VEGFRs), platelet-derived growth factor receptors (PDGFRs) and c-Kit have been shown to be…”
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Cytokine Release Syndrome and Associated Acute Toxicities in Pediatric Patients Undergoing Immune Effector Cell Therapy or Hematopoietic Cell Transplantation
Published in Frontiers in oncology (24-03-2022)“…Immune effector cells (IEC) are a powerful and increasingly targeted tool, particularly for the control and eradication of malignant diseases. However, the…”
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Continuous and differential improvement in worldwide access to hematopoietic cell transplantation: activity has doubled in a decade with a notable increase in unrelated and non-identical related donors
Published in Haematologica (Roma) (09-05-2024)“…Promoting access to and excellence in hematopoietic cell transplantation (HCT) by collecting and disseminating data on global HCT activities is one of the…”
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Global characteristics and outcomes of autologous hematopoietic stem cell transplantation for newly diagnosed multiple myeloma: A study of the worldwide network for blood and marrow transplantation (WBMT)
Published in American journal of hematology (01-11-2024)“…Autologous hematopoietic cell transplantation (AHCT) is a commonly used treatment in multiple myeloma (MM). However, real‐world global demographic and outcome…”
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Integration of measurable residual disease by WT1 gene expression and flow cytometry identifies pediatric patients with high risk of relapse in acute myeloid leukemia
Published in Frontiers in oncology (24-04-2024)“…Molecular testing plays a pivotal role in monitoring measurable residual disease (MRD) in acute myeloid leukemia (AML), aiding in the refinement of risk…”
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Hematopoietic stem cell transplantation from HLA-matched sibling donors in children with acute lymphoblastic leukemia: A report from the Children’s Cancer Hospital Egypt
Published in Frontiers in oncology (27-09-2022)“…Introduction Allogeneic hematopoietic stem cell transplantation (HSCT) is widely used for high-risk acute lymphoblastic leukemia (ALL) patients in their first…”
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The role of registries in hematological disorders
Published in Best practice & research. Clinical haematology (01-06-2024)“…Hematopoietic cell transplantation (HCT) was developed more than 65 years ago to treat malignant blood disorders and irreversible bone marrow failures, with…”
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PB2226: HIGH RISK LANGERHANS CELL HISTIOCYTOSIS (LCH) IN CHILDREN: THE ROLE OF CLADRIBINE SALVAGE IN IMPROVING THE OUTCOME. A SINGLE CENTER EXPERIENCE
Published in HemaSphere (08-08-2023)Get full text
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PB2222: DOES LUNG LESION SEVERITY AFFECT THE OUTCOME IN PEDIATRIC PULMONARY MULTISYSTEM LANGERHANS CELL HISTIOCYTOSIS?
Published in HemaSphere (08-08-2023)Get full text
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Plasma miRNA expression profile in pediatric pineal pure germinomas
Published in Frontiers in oncology (11-04-2024)“…Pure germinomas account for 40% of pineal tumors and are characterized by the lack of appreciable tumor markers, thus requiring a tumor biopsy for diagnosis…”
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An overview of childhood cancer care and outcomes in Egypt: a narrative review
Published in Ecancermedicalscience (2024)“…Childhood cancer is an urgent priority in Egypt, owing to a large number of children with cancer, the great need and demand for paediatric oncology services,…”
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SARS-CoV-2 genome variations and evolution patterns in Egypt: a multi-center study
Published in Scientific reports (25-08-2022)“…A serious global public health emergency emerged late November 2019 in Wuhan City, China, by a new highly pathogenic virus, SARS-CoV-2. The virus evolution…”
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Barriers and Facilitators to Implementing Cost-Effective Evidence-Based Childhood Cancer Treatment in a Resource-Limited Setting in Egypt: A Qualitative Interview Study
Published in JCO global oncology (01-06-2023)“…Childhood cancer treatment is complex, resource-intensive, and expensive, and resource-limited settings would benefit from providing cost-effective treatment…”
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P552: MEASURABLE RESIDUAL DISEASE DETECTED BY WT1 IS AN INDEPENDENT PREDICTOR OF SURVIVAL IN CHILDREN WITH ACUTE MYELOID LEUKEMIA
Published in HemaSphere (08-08-2023)Get full text
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Special issues related to the diagnosis and management of acquired aplastic anemia in countries with restricted resources, a report on behalf of the Eastern Mediterranean blood and marrow transplantation (EMBMT) group and severe aplastic anemia working party of the European Society for blood and marrow transplantation (SAAWP of EBMT)
Published in Bone marrow transplantation (Basingstoke) (01-10-2021)“…Aplastic anemia is a relatively rare but potentially fatal disorder, with a reported higher incidence in developing countries in comparison to the West. There…”
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Outcome of hematopoietic stem cell transplantation (HCT) from HLA-matched related donor for Fanconi anemia (FA) in adolescents and adults: a retrospective study by Eastern Mediterranean Blood and Marrow Transplantation Group (EMBMT)
Published in Bone marrow transplantation (Basingstoke) (01-07-2020)“…Hematopoietic Stem Cell Transplantation (HSCT) is the only potentially curative treatment option for the hematologic complications that occur in patients with…”
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Comparison of toxicity following different conditioning regimens (busulfan/melphalan and carboplatin/etoposide/melphalan) for advanced stage neuroblastoma: Experience of two transplant centers
Published in Pediatric transplantation (01-03-2016)“…The outcome for advanced neuroblastoma has improved with combined modality therapy: induction chemotherapy, surgery, and consolidation with high‐dose…”
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HEMATOPOIETIC STEM CELL TRANSPLANTATION IN EGYPT CHALLENGES AND SOLUTIONS
Published in Mediterranean journal of hematology and infectious diseases (27-04-2020)“…Hematopoietic stem cell transplantation (HSCT) is now an established treatment modality with definitive indications for many hematological disorders. However,…”
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