Search Results - "El Sayyed, Hafez"
-
1
Mapping Topoisomerase IV Binding and Activity Sites on the E. coli Genome
Published in PLoS genetics (12-05-2016)“…Catenation links between sister chromatids are formed progressively during DNA replication and are involved in the establishment of sister chromatid cohesion…”
Get full text
Journal Article -
2
Break-ups and make-ups: DNA search and repair
Published in Nature reviews. Microbiology (01-02-2022)“…This month’s Under the Lens discusses how recent advanced microscopy studies have provided insights into key target-search mechanisms that allow the…”
Get full text
Journal Article -
3
Transcription factor dynamics in plants: Insights and technologies for in vivo imaging
Published in Plant physiology (Bethesda) (03-05-2022)“…Biochemical and genetic approaches have been extensively used to study transcription factor (TF) functions, but their dynamic behaviors and the complex ways in…”
Get full text
Journal Article -
4
Extended sister-chromosome catenation leads to massive reorganization of the E. coli genome
Published in Nucleic acids research (21-03-2022)“…Abstract In bacteria, chromosome segregation occurs progressively from the origin to terminus within minutes of replication of each locus. Between replication…”
Get full text
Journal Article -
5
RNA polymerase redistribution supports growth in E. coli strains with a minimal number of rRNA operons
Published in Nucleic acids research (25-08-2023)“…Abstract Bacterial transcription by RNA polymerase (RNAP) is spatially organized. RNAPs transcribing highly expressed genes locate in the nucleoid periphery,…”
Get full text
Journal Article -
6
Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes
Published in Microbial cell (07-01-2019)“…Genomes are constantly in flux, undergoing changes due to recombination, repair and mutagenesis. , many of such changes are studies using reporters for…”
Get full text
Journal Article -
7
Mapping E. coli Topoisomerase IV Binding and Activity Sites
Published in Methods in molecular biology (Clifton, N.J.) (2018)“…This methods article described a protocol aiming at mapping E. coli Topoisomerase IV (Topo IV) binding and cleavage activity sites on the genome. The approach…”
Get more information
Journal Article -
8
Infection Inspection: using the power of citizen science for image-based prediction of antibiotic resistance in Escherichia coli treated with ciprofloxacin
Published in Scientific reports (22-08-2024)“…Antibiotic resistance is an urgent global health challenge, necessitating rapid diagnostic tools to combat its threat. This study uses citizen science and…”
Get full text
Journal Article -
9
Fungal lysis by a soil bacterium fermenting cellulose
Published in Environmental microbiology (01-08-2015)“…Summary Recycling of plant biomass by a community of bacteria and fungi is fundamental to carbon flow in terrestrial ecosystems. Here we report how the plant…”
Get full text
Journal Article -
10
Engineering stress as a motivation for filamentous virus morphology
Published in Biophysical reports (10-09-2024)“…Many viruses are pleomorphic in shape and size, with pleomorphism often thought to correlate with infectivity, pathogenicity, or virus survival. For example,…”
Get full text
Journal Article -
11
Deep learning and single-cell phenotyping for rapid antimicrobial susceptibility detection in Escherichia coli
Published in Communications biology (14-11-2023)“…The rise of antimicrobial resistance (AMR) is one of the greatest public health challenges, already causing up to 1.2 million deaths annually and rising…”
Get full text
Journal Article -
12
Single-molecule tracking reveals the functional allocation, in vivo interactions, and spatial organization of universal transcription factor NusG
Published in Molecular cell (07-03-2024)“…During transcription elongation, NusG aids RNA polymerase by inhibiting pausing, promoting anti-termination on rRNA operons, coupling transcription with…”
Get more information
Journal Article