Search Results - "El Sayed, Naglaa"
-
1
Dual-adhesive and self-healing alginate-based hydrogel for wound healing
Published in Chemical papers (01-01-2024)“…Some of the wound dressings on the market cause skin tearing and bleeding when removed, slowing the healing process. So, it is difficult to treat infected…”
Get full text
Journal Article -
2
A sustainable approach for linen dyeing and finishing with natural lac dye through chitosan bio-mordanting and microwave heating
Published in Journal of engineered fibers and fabrics (01-01-2023)“…Sustainability has become a global requirement in all industries. In the textile sector sustainability can be achieved by developing innovative techniques,…”
Get full text
Journal Article -
3
Design, synthesis, biological evaluation, and molecular docking of new benzofuran and indole derivatives as tubulin polymerization inhibitors
Published in Drug development research (01-04-2022)“…Microtubules and the mitotic spindle have become an important target for cancer treatment due to their critical role in cell division. In this work, a novel…”
Get full text
Journal Article -
4
Farnesyl pyrophosphate synthase inhibitors with antiosteoporosis efficacy in ovariectomized rats: A mixed binding approach beyond bisphosphonates
Published in European journal of medicinal chemistry (05-10-2024)“…The primary focus of bisphosphonate medications is on targeting human farnesyl pyrophosphate synthase (hFPPS), an essential regulator of mammalian isoprenoids…”
Get full text
Journal Article -
5
Subtype‐selective positive modulation of KCa2 channels depends on the HA/HB helices
Published in British journal of pharmacology (01-02-2022)“…Background and Purpose In the activated state of small‐conductance Ca2+‐activated potassium (KCa2) channels, calmodulin interacts with the HA/HB helices and…”
Get full text
Journal Article -
6
Exploring internship nursing students’ perception of gerontological nursing competencies: A descriptive study at Cairo University Hospitals
Published in Journal of integrative nursing (01-10-2023)“…Objective: This research study explores the perceptions of gerontological nursing competencies, attitudes toward older individuals, and the willingness to…”
Get full text
Journal Article -
7
Design, Synthesis, and Evaluation of Homochiral Peptides Containing Arginine and Histidine as Molecular Transporters
Published in Molecules (Basel, Switzerland) (29-06-2018)“…Linear (HR) and cyclic [HR] peptides (n = 4,5) containing alternate arginine and histidine residues were synthesized. The peptides showed 0⁻15% cytotoxicity at…”
Get full text
Journal Article -
8
Synthesis and evaluation of a new series of spiro aryl dioxolane compounds: A new scaffold as potential poly(ADP‐ribose)polymerase‐1 (PARP‐1) inhibitors
Published in Journal of heterocyclic chemistry (01-11-2022)“…A new series of spiro aryl dioxolane derivatives were synthesized and evaluated to find a new scaffold as potential poly(ADP‐ribose)polymerases‐1 (PARP‐1)…”
Get full text
Journal Article -
9
Preparation of novel azidopyrazole derivatives with anticipated cytotoxic and antimicrobial activities
Published in Journal of heterocyclic chemistry (01-03-2020)“…The reactions of azidopyrazole with some of primary amines and active methylene compounds were studied. Structures of the prepared compounds were identified…”
Get full text
Journal Article -
10
Cyclic Peptide Containing Hydrophobic and Positively Charged Residues as a Drug Delivery System for Curcumin
Published in Current drug delivery (01-05-2016)“…Due to the low water solubility and hydrophobic nature of curcumin, an efficient cellular uptake is critical for its biological activity. We have previously…”
Get more information
Journal Article -
11
Adiponectin and its polymorphism: relation to coronary artery disease
Published in The Egyptian journal of internal medicine (01-07-2019)“…En Background Adiponectin is an adipocytokine with important role in atherosclerosis. Increasing interest has been directed toward the role of adiponectin gene…”
Get full text
Journal Article -
12
Kaposi Sarcoma in the Context of Post‐Modified Radical Mastectomy: A New Case Report and Brief Review
Published in Journal of cutaneous pathology (04-11-2024)“…Kaposi sarcoma is a human herpesvirus 8–associated angio‐proliferative tumor arising from lymphatic endothelial cells. Four clinical subtypes are known:…”
Get full text
Journal Article -
13
Design, synthesis and biological evaluation of novel α-aminophosphonate oxadiazoles via optimized iron triflate catalyzed reaction as apoptotic inducers
Published in European journal of medicinal chemistry (15-10-2019)“…α-aminophosphonate oxadiazoles (5a-m) were prepared in high yields by reacting of 1,3,4-oxadiazole acetohydrazide (3) with appropriate aldehydes and diethyl…”
Get full text
Journal Article -
14
Response of the modified GAFCHROMIC EBT2 radiochromic film to DC glow discharge plasma
Published in Scientific reports (27-01-2024)“…The response of the modified GAFCHROMIC EBT2 radiochromic film to DC Oxygen glow discharge plasma was investigated using a flatbed scanner and an UV–Vis…”
Get full text
Journal Article -
15
Subtype-selective positive modulation of KCa 2 channels depends on the HA/HB helices
Published in British journal of pharmacology (01-02-2022)Get full text
Journal Article -
16
Subtype-selective positive modulation of K Ca 2 channels depends on the HA/HB helices
Published in British journal of pharmacology (01-02-2022)“…In the activated state of small-conductance Ca -activated potassium (K 2) channels, calmodulin interacts with the HA/HB helices and the S4-S5 linker. CyPPA…”
Get full text
Journal Article -
17
Coupling of 3-Aminopropyl Sulfonic Acid to Cellulose Nanofibers for Efficient Removal of Cationic Dyes
Published in Materials (01-10-2022)“…A novel anionic nanostructured cellulose derivate was prepared through the coupling of TEMPO-oxidized cellulose nanofibers with 3-aminopropyl sulfonic acid…”
Get full text
Journal Article -
18
Synthesis, biological evaluation and molecular docking of new sulfonamide-based indolinone derivatives as multitargeted kinase inhibitors against leukemia
Published in Bioorganic chemistry (01-12-2021)“…[Display omitted] •Novel sulfonamide-based 3-indolinones were synthesized.•All compounds were evaluated for their cytotoxicity against 60 cell lines.•Compound…”
Get full text
Journal Article -
19
Synthesis and characterization of new tetrakisphosphonic acid derivatives as FPPS inhibitors and evaluation of their anti-osteoclastogenic potential for prevention of osteoporosis
Published in Medicinal chemistry research (01-07-2024)“…Numerous bone illnesses, including osteoporosis, are brought on by abnormal osteoclast differentiation. The identification of effective strategies for…”
Get full text
Journal Article -
20
Synthesis, molecular docking and biological evaluation of 2-(thiophen-2-yl)-1H-indoles as potent HIV-1 non-nucleoside reverse transcriptase inhibitors
Published in Bioorganic chemistry (01-01-2020)“…[Display omitted] •New phosphoindole derivatives were synthesized.•All the compounds were evaluated as potent HIV-1 non-nucleoside reverse transcriptase…”
Get full text
Journal Article