Search Results - "El Kouri, C."

Impact of geriatric risk factors on pegylated liposomal doxorubicin tolerance and efficacy in elderly metastatic breast cancer patients: Final results of the DOGMES multicentre GINECO trial by Falandry, C, Brain, E, Bonnefoy, M, Mefti, F, Jovenin, N, Rigal, O, Guillem, O, El Kouri, C, Uwer, L, Abadie-Lacourtoisie, S, Cretin, J, Jacquin, J.P, Paraiso, D, Freyer, G

“…Abstract Background Metastatic breast cancer chemotherapy in the elderly is considered effective in carefully selected patients, but there is little data…”
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Use of protamine to augment adenovirus-mediated cancer gene therapy by LANUTI, M, EL KOURI, C, FORCE, S. D, CHANG, M. Y, AMIN, K, XU, K, BLAIR, I. A, KAISER, L. R, ALBELDA, S. M

“…Improving the therapeutic potential of adenoviral (Ad) suicide gene therapy has become an area of intense investigation since the inception of gene therapy…”
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465P Larotracking: Real-life study of locally advanced/metastatic solid tumor treated with larotrectinib in French expanded access program by Dufresne, A., Huillard, O., Dalban, C., Geier, M., Wassermann, J., Zanetta, S., Cabourg, M., Catargi, B., El Kouri, C., Hrab, I., Laramas, M., Moreira, A., Saada, E.B., Tournigand, C., Valentin, T., Vauleon, E., Mayet, R., Perol, D., Blay, J-Y.

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Randomized open-label controlled study of cancer vaccine OSE2101 versus chemotherapy in HLA-A2-positive patients with advanced non-small-cell lung cancer with resistance to immunotherapy: ATALANTE-1 by Besse, B., Felip, E., Garcia Campelo, R., Cobo, M., Mascaux, C., Madroszyk, A., Cappuzzo, F., Hilgers, W., Romano, G., Denis, F., Viteri, S., Debieuvre, D., Galetta, D., Baldini, E., Razaq, M., Robinet, G., Maio, M., Delmonte, A., Roch, B., Masson, P., Schuette, W., Zer, A., Remon, J., Costantini, D., Vasseur, B., Dziadziuszko, R., Giaccone, G., Zemanová, M., Besse, B., Bonnet, C., Cadranel, J., Chouaid, C., Cortot, A., Debieuvre, D., Delclaux, B., Denis, F., Duchemann, B., El Kouri, C., Ferrand, F.R., Ginoux, M., Hilgers, W., Madroszyk, A., Masson, P., Mazieres, J., Molinier, O., Moro-Sibilot, D., Pichon, E., Mascaux, C., Robinet, G., Roch, B., Zalcman, G., Schmidtke-Schrezenmeier, G., Schuette, W., Urban, L., Gottfried, M., Nechushtan, H., Peled, N., Wollner, M., Zer, A., Baldini, E., Bonanno, L., Bonetti, A., Cappuzzo, F., Delmonte, A., Galetta, D., Maio, M., Minotti, V., Rea, A., Romano, G., Tassinari, D., Tonini, G., Dziadziuszko, R., Karaszewska, B., Szczęsna, A., Cobo, M., De Castro, J., Felip, E., Garcia Campelo, M.R., Hernández, A., Moran, T., Provencio, M., Viteri, S., Dasgupta, A., Gabrail, N., Giaccone, G., Harshad, A., Liu, S., Oubre, D., Panikkar, R., Razaq, M., Sanborn, R.

“…Patients with advanced non-small-cell lung cancer (NSCLC) treated with immune checkpoint blockers (ICBs) ultimately progress either rapidly (primary…”
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French (lapatinib) authorization for temporary use (ATU) – design, operation and initial safety data by Campone, M, El-Kouri, C, Cottu, P, Otmezguine, D.R, Guastalla, J.R, Gligorov, J, Antoine, E.C, Petit, T, Ferriere, J.R, Goncalves, A

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250PEGFR TESTING FROM CIRCULATING CELL-FREE DNA: READY FOR ROUTINE PRACTICE by Denis, M.G., Vallee, A., El Kouri, C., Lacroix, H., Marcq, M., Bizieux, A., Bennouna, J., Douillard, J.

“…Abstract Aim: Detection of EGFR alterations is critical for predicting the response to tyrosine kinase inhibitors (TKI) in patients with non-small-cell lung…”
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Egfr Testing from Circulating Cell-Free Dna: Ready for Routine Practice by Denis, M.G., Vallee, A., El Kouri, C., Lacroix, H., Marcq, M., Bizieux, A., Bennouna, J., Douillard, J.

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Non pegylated liposomal doxorubicin (npld, myocettm) + carboplatin (cb) in patients (pts) with ovarian cancer in late relapse (oclr): a phase 2 gineco study by You, B., Joly, F., Ray-Coquard, I.L., El Kouri, C., Mercier-Blas, A., Berton-Rigaud, D., Kalbacher, E., Cojocarasu, O., Fabbro, M., Cretin, J., Zannetti, A., Abadie-Lacourtoisie, S., Mollon, D., Hardy-Bessard, A.-C., Provansal, M., Freyer, G.

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Les hypercalcémies malignes: étude rétrospective sur 150 patients by Lortholary, A., El Kouri, C., Ramée, J. -F., Morineau, N., Maillet, F., Le Gouill, C., Terzidis-Mallat, E., Pauvreau, O., Cochery, T., Pioud-Martigny, R., Bonnard, D., Mahot, P.

“…Résumé Introduction Une hypercalcémie est fréquemment retrouvée chez les patients atteints de cancer. L’objectif de cette étude était d’évaluer l’épidémiologie…”
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1584P - Home-Based Zoledronic Acid (ZOL) Infusion Therapy in Patients with Solid Tumours: Compliance and Patient-Nurse Satisfaction by Lebret, T., Mouysset, J., Lortholary, A., El Kouri, C., Bastit, L., Ktiouet, M., Slimane, K., Muracciole, X., Guérif, S.

“…To explore patient and nurse satisfaction, compliance with practice guidelines, technical feasibility, and safety of home infusion of the bisphosphonate ZOL…”
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Home-Based Zoledronic Acid (ZOL) Infusion Therapy in Patients with Solid Tumours: Compliance and Patient-Nurse Satisfaction by Lebret, T., Mouysset, J., Lortholary, A., El Kouri, C., Bastit, L., Ktiouet, M., Slimane, K., Muracciole, X., Guérif, S.

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Essor Study: Oral Chemotherapies for Oncology Practices: a Retrospective Analysis in the Community Setting for Selected Drugs by Grude, F., Douillard, J., El Kouri, C., Donny, P., Urbanski, M., Chaslerie, A., Piau, S., Bourgeois, H., Metges, J., Pivette, J.

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Impact of geriatric vulnerability parameters on pegylated liposomal doxorubicin (PLD) tolerance and outcome in elderly patients with metastatic breast cancer: Results of the DOGMES multicenter phase II GINECO trial by Falandry, C., Brain, E., Bonnefoy, M., Mefti, F., Savoye, A., Rigal, O., Oddou-Lagranière, S., El Kouri, C., Uwer, L., Abadie-Lacourtoisie, S., Cretin, J., Jacquin, J., Freyer, G.

“…Abstract only…”
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Abstract S1-6: TAMRAD: A GINECO Randomized Phase II Trial of Everolimus in Combination with Tamoxifen Versus Tamoxifen Alone in Patients (pts) with Hormone-Receptor Positive, HER2 Negative Metastatic Breast Cancer (MBC) with Prior Exposure to Aromatase Inhibitors (AI) by Bachelot, T, Bourgier, C, Cropet, C, Guastalla, J-P, Ferrero, J-M, Leger-Falandry, C, Soulie, P, Eymard, J-C, Debled, M, Spaeth, D, Legouffe, E, Delozier, T, El Kouri, C, Chidiac, J.

“…Abstract Background: Resistance to hormonal therapy may be associated with activation of the PI3K/AKT pathway. Preclinically, everolimus (RAD), an oral…”
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9072 POSTER Pemetrexed (Pern) Maintenance Therapy in Elderly Patients (Pts) With Good Performance Status (PS) – Analysis of PARAMOUNT Phase III Study of Pern Versus Placebo in Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) by Gridelli, C, Thomas, M, Prabhash, K, Kouri, C. El, Blackhall, F, Melemed, S, Zimmermann, A, Chouaki, N, Visseren-Grul, C, Paz-Ares, L.G

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Immune-dependent distant bystander effect after adenovirus-mediated suicide gene transfer in a rat model of liver colorectal metastasis by Agard, C, Ligeza, C, Dupas, B, Izembart, A, El Kouri, C, Moullier, P, Ferry, N

“…Gene transfer of the herpes simplex virus thymidine kinase (HSV-tk) gene sensitizes tumor cells to the toxic effect of ganciclovir (GCV). The toxic effect of…”
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Evaluation of an E1E4-deleted adenovirus expressing the herpes simplex thymidine kinase suicide gene in cancer gene therapy by Lanuti, M, Gao, G P, Force, S D, Chang, M Y, El Kouri, C, Amin, K M, Hughes, J V, Wilson, J M, Kaiser, L R, Albelda, S M

“…Studies with first-generation adenoviral vectors have uncovered limitations that include finite transgene persistence, potential hepatotoxicity, and…”
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The evaluation of adenoviral p53-mediated bystander effect in gene therapy of cancer by Rizk, N P, Chang, M Y, El Kouri, C, Seth, P, Kaiser, L R, Albelda, S M, Amin, K M

“…Because many tumors have mutated p53, one potential strategy proposed for cancer gene therapy is the introduction of the wild-type p53 gene into tumor cells…”
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