Search Results - "El Kadhi, Khaled Ben"

The Inositol 5-Phosphatase dOCRL Controls PI(4,5)P2 Homeostasis and Is Necessary for Cytokinesis by Ben El Kadhi, Khaled, Roubinet, Chantal, Solinet, Sara, Emery, Grégory, Carréno, Sébastien

“…During cytokinesis, constriction of an equatorial actomyosin ring physically separates the two daughter cells. At the cleavage furrow, the phosphoinositide…”
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The actin-binding ERM protein Moesin binds to and stabilizes microtubules at the cell cortex by Solinet, Sara, Mahmud, Kazi, Stewman, Shannon F, Ben El Kadhi, Khaled, Decelle, Barbara, Talje, Lama, Ma, Ao, Kwok, Benjamin H, Carreno, Sébastien

“…Ezrin, Radixin, and Moesin (ERM) proteins play important roles in many cellular processes including cell division. Recent studies have highlighted the…”
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Interdomain allosteric regulation of Polo kinase by Aurora B and Map205 is required for cytokinesis by Kachaner, David, Pinson, Xavier, El Kadhi, Khaled Ben, Normandin, Karine, Talje, Lama, Lavoie, Hugo, Lépine, Guillaume, Carréno, Sébastien, Kwok, Benjamin H, Hickson, Gilles R, Archambault, Vincent

“…Drosophila melanogaster Polo and its human orthologue Polo-like kinase 1 fulfill essential roles during cell division. Members of the Polo-like kinase (Plk)…”
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PTEN reduces endosomal PtdIns(4,5)P2 in a phosphatase-independent manner via a PLC pathway by Mondin, Virginie E., Ben El Kadhi, Khaled, Cauvin, Clothilde, Jackson-Crawford, Anthony, Bélanger, Emilie, Decelle, Barbara, Salomon, Rémi, Lowe, Martin, Echard, Arnaud, Carréno, Sébastien

“…The tumor suppressor PTEN dephosphorylates PtdIns(3,4,5)P3 into PtdIns(4,5)P2. Here, we make the unexpected discovery that in Drosophila melanogaster PTEN…”
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NF45 and NF90 Regulate Mitotic Gene Expression by Competing with Staufen-Mediated mRNA Decay by Nourreddine, Sami, Lavoie, Geneviève, Paradis, Justine, Ben El Kadhi, Khaled, Méant, Antoine, Aubert, Léo, Grondin, Benoit, Gendron, Patrick, Chabot, Benoit, Bouvier, Michel, Carreno, Sébastien, Roux, Philippe P.

“…In human cells, the expression of ∼1,000 genes is modulated throughout the cell cycle. Although some of these genes are controlled by specific transcriptional…”
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DHTP is an allosteric inhibitor of the kinesin‐13 family of microtubule depolymerases by Talje, Lama, El Kadhi, Khaled Ben, Atchia, Kaleem, Tremblay‐Boudreault, Thierry, Carreno, Sébastien, Kwok, Benjamin H.

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The unexpected role of Drosophila OCRL during cytokinesis by Ben El Kadhi, Khaled, Emery, Grégory, Carreno, Sebastien

“…Inositides are intrinsic components of cell membranes that regulate a wide variety of cellular functions. PtdIns(4,5)P 2, one of the most abundant…”
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IPIP27 Coordinates PtdIns(4,5)P 2 Homeostasis for Successful Cytokinesis by Carim, Sabrya C, Ben El Kadhi, Khaled, Yan, Guanhua, Sweeney, Sean T, Hickson, Gilles R, Carréno, Sébastien, Lowe, Martin

“…During cytokinesis, an actomyosin contractile ring drives the separation of the two daughter cells. A key molecule in this process is the inositol lipid…”
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PTEN reduces endosomal PtdIns(4,5)P 2 in a phosphatase-independent manner via a PLC pathway by Mondin, Virginie E, Ben El Kadhi, Khaled, Cauvin, Clothilde, Jackson-Crawford, Anthony, Bélanger, Emilie, Decelle, Barbara, Salomon, Rémi, Lowe, Martin, Echard, Arnaud, Carréno, Sébastien

“…The tumor suppressor PTEN dephosphorylates PtdIns(3,4,5)P into PtdIns(4,5)P Here, we make the unexpected discovery that in PTEN reduces PtdIns(4,5)P levels on…”
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IPIP27 Coordinates PtdIns(4,5)P2 Homeostasis for Successful Cytokinesis by Carim, Sabrya C., Ben El Kadhi, Khaled, Yan, Guanhua, Sweeney, Sean T., Hickson, Gilles R., Carréno, Sébastien, Lowe, Martin

“…During cytokinesis, an actomyosin contractile ring drives the separation of the two daughter cells. A key molecule in this process is the inositol lipid…”
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Proteomics Screen Identifies Class I Rab11 Family Interacting Proteins as Key Regulators of Cytokinesis by Laflamme, Carl, Galan, Jacob A., Ben El Kadhi, Khaled, Méant, Antoine, Zeledon, Carlos, Carréno, Sébastien, Roux, Philippe P., Emery, Gregory

“…The 14-3-3 protein family orchestrates a complex network of molecular interactions that regulates various biological processes. Owing to their role in…”
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DHTP is an allosteric inhibitor of the kinesin-13 family of microtubule depolymerases by Talje, Lama, Ben El Kadhi, Khaled, Atchia, Kaleem, Tremblay-Boudreault, Thierry, Carreno, Sébastien, Kwok, Benjamin H.

“…•An ATPase-based high-throughput screen identified a kinesin-13 inhibitor DHTP.•DHTP inhibits kinesin-13 in a non ATP-competitive manner.•DHTP is cell…”
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