Search Results - "El Jammal, Thomas"
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Autophagy and Mitophagy-Related Pathways at the Crossroads of Genetic Pathways Involved in Familial Sarcoidosis and Host-Pathogen Interactions Induced by Coronaviruses
Published in Cells (Basel, Switzerland) (01-08-2021)“…Sarcoidosis is a multisystem disease characterized by the development and accumulation of granulomas, the hallmark of an inflammatory process induced by…”
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JAK inhibitors for the treatment of autoimmune and inflammatory diseases
Published in Autoimmunity reviews (01-11-2019)“…Cytokines play a central role in the pathophysiology of autoimmune and inflammatory diseases. Several cytokines signal through the JAK-STAT pathway, which is…”
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Whole exome sequencing of a German sarcoidosis family with four affected and one spontaneous remission case
Published in Rheumatology (Oxford, England) (03-05-2024)“…Abstract Objectives To analyse genetic mechanisms triggering familial sarcoidosis, whole exome screening of a family of six persons with four cases of…”
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Sarcoidosis: A Clinical Overview from Symptoms to Diagnosis
Published in Cells (Basel, Switzerland) (31-03-2021)“…Sarcoidosis is a multi-system disease of unknown etiology characterized by the formation of granulomas in various organs. It affects people of all ethnic…”
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Refractory Sarcoidosis: A Review
Published in Therapeutics and clinical risk management (01-01-2020)“…Sarcoidosis is a multi-system disease of unknown etiology characterized by granuloma formation in various organs (especially lung and mediastinohilar lymph…”
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State of the art: approved and emerging JAK inhibitors for rheumatoid arthritis
Published in Expert opinion on pharmacotherapy (22-01-2021)“…Rheumatoid arthritis (RA) is the most common autoimmune inflammatory arthritis in adults. In the past decade, many treatments have emerged to expand the…”
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Sarcoidosis and Cancer: A Complex Relationship
Published in Frontiers in medicine (24-11-2020)“…Sarcoidosis is a systemic disease of unknown etiology, characterized by the presence of non-caseating granulomas in various organs, mainly the lungs, and the…”
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Sarcoidosis-Related Uveitis: A Review
Published in Journal of clinical medicine (29-04-2023)“…Sarcoidosis is an inflammatory disease that involves the eyes in 10-55% of cases, sometimes without systemic involvement. All eye structures can be affected,…”
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Extreme Hyperferritinemia: Causes and Prognosis
Published in Journal of clinical medicine (16-09-2022)“…The significance of extreme hyperferritinemia and its association with certain diagnoses and prognoses are not well characterized. We performed a retrospective…”
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Diagnostic value of elevated serum angiotensin-converting enzyme and lymphopenia in patients with granulomatous hepatitis
Published in Sarcoidosis, vasculitis, and diffuse lung diseases (01-01-2023)“…Granulomatous hepatitis (GH) is associated with various aetiologies, especially inflammatory and infectious disorders. Sarcoidosis is a granulomatous disease…”
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Uveitis as an Open Window to Systemic Inflammatory Diseases
Published in Journal of clinical medicine (14-01-2021)“…Spondyloarthritis (Spa), Behçet's disease (BD) and sarcoidosis are major systemic inflammatory diseases worldwide. They are all multisystem pathologies and…”
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Diagnosing Hemophagocytic Lymphohistiocytosis with Machine Learning: A Proof of Concept
Published in Journal of clinical medicine (21-10-2022)“…Hemophagocytic lymphohistiocytosis is a hyperinflammatory syndrome characterized by uncontrolled activation of immune cells and mediators. Two diagnostic tools…”
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Management of Non-Infectious Uveitis, a Selection of Topical Items Updating
Published in Journal of clinical medicine (22-09-2022)“…First of all, we would like to thank all of the authors for their contributions and the editorial staff who enabled the achievement of this «Diagnosis and…”
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Evaluation of Glycosylated Ferritin in Adult-Onset Still's Disease and Differential Diagnoses
Published in Journal of clinical medicine (26-08-2022)“…Glycosylated ferritin (GF) has been reported as a good diagnostic biomarker for adult-onset Still’s disease (AOSD), but only a few studies have validated its…”
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Aging is associated with impaired triggering of TRPV3-mediated cutaneous vasodilation: a crucial process for local heat exposure
Published in GeroScience (01-08-2024)“…Sensing temperature is vitally important to adapt our body to environmental changes. Local warm detection is required to initiate regulation of cutaneous blood…”
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Challenging Mimickers in the Diagnosis of Sarcoidosis: A Case Study
Published in Diagnostics (Basel) (12-07-2021)“…Sarcoidosis is a systemic granulomatous disease of unknown cause characterized by a wide variety of presentations. Its diagnosis is based on three major…”
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Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions
Published in Autoimmunity reviews (01-07-2020)“…The coronavirus disease-19 pandemic (COVID-19), which appeared in China in December 2019 and rapidly spread throughout the world, has forced clinicians and…”
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Extrapulmonary sarcoidosis
Published in Journal of autoimmunity (05-10-2024)“…Sarcoidosis is a chronic disease of unknown origin that develops when a genetically susceptible host is exposed to an antigen, leading to an exuberant immune…”
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Hydroxychloroquine Therapy in Sarcoidosis-Associated Uveitis
Published in Ocular immunology and inflammation (07-02-2024)“…To assess the efficacy and tolerance of hydroxychloroquine in sarcoidosis-associated uveitis Retrospective study on all patients with sarcoidosis-associated…”
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Identification of Multidimensional Phenotypes Using Cluster Analysis in Sarcoid Uveitis Patients
Published in American journal of ophthalmology (01-10-2022)“…PURPOSETo identify multidimensional phenotypes of sarcoid uveitis patients.DESIGNRetrospective cohort.METHODSConsecutive patients with biopsy-proven, presumed,…”
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