Search Results - "El Fahime, Elmostafa"
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Systematic review and meta-analysis for the biotechnological production of THC in Morocco
Published in E3S Web of Conferences (01-01-2021)“…Cannabinoids have promising therapeutic potential. Δ9-tetrahydrocannabinol (THC), the most important psychotropic active ingredient of Cannabis Sativa L, has…”
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Prevalence of the protective OAS1 rs10774671-G allele against severe COVID-19 in Moroccans: implications for a North African Neanderthal connection
Published in Archives of virology (01-05-2024)“…The clinical presentation of COVID-19 shows high variability among individuals, which is partly due to genetic factors. The OAS1/2/3 cluster has been found to…”
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Development of a new experimental NMR strategy for covalent cysteine protease inhibitors screening: toward enhanced drug discovery
Published in RSC advances (22-08-2024)“…In the development of antiviral drugs, proteases and polymerases are among the most important targets. Cysteine proteases, also known as thiol proteases,…”
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Improvement of the Chemical Reactivity of Michael Acceptor of Ethacrynic Acid Correlates with Antiproliferative Activities
Published in Molecules (Basel, Switzerland) (01-01-2023)“…The present study aims to report the design, synthesis, and biological activity of new ethacrynic acid ( ) analogs ( ) obtained by the double modulation of the…”
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Exploring the hemicellulolytic properties and safety of Bacillus paralicheniformis as stepping stone in the use of new fibrolytic beneficial microbes
Published in Scientific reports (20-12-2023)“…Bacillus strains from the Moroccan Coordinated Collections of Microorganisms (CCMM) were characterised and tested for fibrolytic function and safety properties…”
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Draft genome sequence of a mosquito repellent Bacillus licheniformis strain Ba1 isolated from desert soil
Published in Microbiology resource announcements (14-12-2023)“…Microbial volatile organic compounds have been shown to affect a wide insect behavior. In this paper, we report the draft genome sequence of strain Ba1…”
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Contribution of BRCA1 and BRCA2 germline mutations to early onset breast cancer: a series from north of Morocco
Published in BMC cancer (07-09-2020)“…To date, the contribution of BRCA1/2 mutations in Moroccan early onset breast cancer patients remains unknown. Here we assess these genetic alterations for the…”
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Effectiveness of Sinopharm's BBIBP-CorV Booster Vaccination against COVID-19-Related Severe and Critical Cases and Deaths in Morocco during the Omicron Wave
Published in Vaccines (Basel) (27-02-2024)“…This study investigates the effectiveness of the 1st booster dose against COVID-19 severe and critical hospitalizations and deaths occurring due to the Omicron…”
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Circulating microRNA profiles in Wilms tumour (WT): A systematic review and meta-analysis of diagnostic test accuracy
Published in Non-coding RNA research (01-09-2023)“…Wilms tumour (WT) is caused by aberrant embryonic kidney development and associated with dysregulated expression of short, non-protein-coding RNAs termed…”
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Novel ITGB2 Mutation Is Responsible for a Severe Form of Leucocyte Adhesion Deficiency Type 1
Published in BioMed research international (03-03-2022)“…Leukocyte adhesion deficiency type 1 (LAD1) is a rare autosomal recessive hereditary disorder characterized by recurrent infections, impaired pus formation,…”
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Formulation and Physicochemical Characterization of Terpenocannabinoid-Functionalized Hemp Oil Emulsifier: Assessment of Topical Anti-Inflammatory, Antinociceptive, Wound Healing Activity and Cutaneous Toxicity Effects
Published in Scientia pharmaceutica (01-09-2024)“…This article presents a comprehensive study on the formulation and physicochemical characterization of a novel terpenocannabinoid-functionalized hemp oil…”
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Journal Article -
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SARS-CoV-2-Neutralizing Antibody Response and Correlation of Two Serological Assays with Microneutralization
Published in Vaccines (Basel) (01-03-2023)“…SARS-CoV-2 has caused a huge pandemic affecting millions of people and resulting innumerous deaths. A better understanding of the correlation between binding…”
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Evidence for zoonotic transmission of species A rotavirus from goat and cattle in nomadic herds in Morocco, 2012–2014
Published in Virus genes (01-10-2020)“…Species A rotaviruses (RVAs) are a leading cause of diarrhea in children and in the young of a large variety of mammalian and avian host species. The purpose…”
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In vitro antagonist activity of cedar Trichoderma species against three cedarwood lignivorous fungi
Published in Scientific African (01-06-2024)“…Cedarwood lignivorous fungi cause significant damage to cedar groves. In Morocco, the losses of cedar wood are estimated at more than 30% due to these fungi,…”
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Use of rpoB gene phylogenetic marker-based distinction of abiotic stress tolerant and plant-growth promoting Bacillus paralicheniformis isolates from their closely related Bacillus licheniformis
Published in Novel research in microbiology journal (01-05-2024)“…Bacillus paralicheniformis is a new identified species, which was distinguished from Bacillus licheniformis in 2015 through extensive phylogenomic and…”
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Journal Article -
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Genome sequencing of severe acute respiratory syndrome COVID-19 EF.1 variant strain obtained from a Moroccan patient
Published in Microbiology resource announcements (11-04-2024)“…Here, we report the identification and coding-complete genome sequence of a severe acute respiratory syndrome COVID-19 (SARS-CoV-2) strain obtained from a…”
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Journal Article -
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Affinity comparison of different THCA synthase to CBGA using modeling computational approaches
Published in Bioinformation (01-01-2014)“…The Δ(9-)Tetrahydrocannabinol (THCA) is the primary psychoactive compound of Cannabis Sativa. It is produced by Δ(1-) Tetrahydrocannabinolic acid synthase…”
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Psychological Distress Associated with Enforced Hospital Isolation Due to COVID-19 during the "Flatten the Curve" Phase in Morocco: A Single-Center Cross-Sectional Study
Published in Healthcare (Basel) (26-02-2024)“…(1) Background: although much research has highlighted the mental health challenges faced by patients in hospital isolation during the COVID-19 pandemic, data…”
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Journal Article -
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Full-length genome analysis of the first human G8P[14] rotavirus strain from Morocco suggests evidence of zoonotic transmission
Published in Virus genes (01-08-2019)“…An unusual group A rotavirus (RVA) strain MAR/ma31/2011/G8P[14] was detected for the first time in Morocco in a stool sample from hospitalized child aged…”
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Journal Article -
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Genetic Characterization and Chemical Identification of Moroccan Cannabis sativa (L.) Seeds: Extraction, and In Vitro and In Silico Biological Evaluation
Published in Plants (Basel) (01-07-2024)“…This study investigated the molecular, phytochemical, and biological aspects of ten local Moroccan traditional landrace seeds. Genetic polymorphisms were…”
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