Environmental exposure to asbestos and the exposure-response relationship with mesothelioma

An epidemiological and environmental study was carried out in Shubra El-Kheima city, greater Cairo, of the exposure-response relationship between asbestos and malignant pleural mesothelioma. Radiological screening was done for 487 people occupationally exposed to asbestos, 2913 environmentally expos...

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Bibliographic Details
Published in:	Eastern Mediterranean health journal Vol. 15; no. 1; pp. 25 - 38
Main Authors:	Madkour, M T, El Bokhary, M S, Awad Allah, H I, Awad, A A, Mahmoud, H F
Format:	Journal Article
Language:	English
Published:	Egypt 01-01-2009
Subjects:	Adult Aged Air Pollutants - adverse effects Air Pollutants - analysis Asbestos - adverse effects Asbestos - analysis Biopsy Case-Control Studies Egypt - epidemiology Environmental Exposure - adverse effects Environmental Exposure - analysis Environmental Monitoring - methods Epidemiological Monitoring Female Humans Inhalation Exposure - adverse effects Inhalation Exposure - analysis Male Mesothelioma - diagnosis Mesothelioma - epidemiology Mesothelioma - etiology Middle Aged Occupational Exposure - adverse effects Occupational Exposure - analysis Pleural Neoplasms - diagnosis Pleural Neoplasms - epidemiology Pleural Neoplasms - etiology Prevalence Residence Characteristics Risk Factors Sex Distribution Statistics, Nonparametric Urban Health - statistics & numerical data Egypt
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Summary:	An epidemiological and environmental study was carried out in Shubra El-Kheima city, greater Cairo, of the exposure-response relationship between asbestos and malignant pleural mesothelioma. Radiological screening was done for 487 people occupationally exposed to asbestos, 2913 environmentally exposed to asbestos and a control group of 979 with no history of exposure. Pleural biopsy was done for suspicious cases. The airborne asbestos fibre concentrations were determined in all areas. There were 88 cases of mesothelioma diagnosed, 87 in the exposed group. The risk of mesothelioma was higher in the environmentally exposed group than other groups, and higher in females than males. The prevalence of mesothelioma increased with increased cumulative exposure to asbestos.
ISSN:	1020-3397 1687-1634
DOI:	10.26719/2009.15.1.25