Search Results - "El‐Maghrabey, Mahmoud"
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Current trends in isotope‐coded derivatization liquid chromatographic‐mass spectrometric analyses with special emphasis on their biomedical application
Published in Biomedical chromatography (01-03-2020)“…Currently, LC–MS has various applications in different areas such as metabolomics, pharmacokinetics, and pathological studies. Yet, matrix effects resulting…”
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Citrus/urea nitrogen‐doped carbon quantum dots as nanosensors for vanillin determination in infant formula and food products via factorial experimental design fluorimetry and smartphone
Published in Luminescence (Chichester, England) (01-02-2024)“…Vanillin is a flavouring agent that is prohibited for use in infant food products with ages lower than 6 months. Excessive vanillin usage could lead to eating…”
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A highly sensitive micelle‐enhanced synchronous spectrofluorimetric determination of the recently approved co‐formulated drugs, bilastine and montelukast in pharmaceuticals and human plasma at nanogram levels
Published in Luminescence (Chichester, England) (01-02-2024)“…In this study, the simultaneous determination of bilastine and montelukast, two recently approved co‐formulated antihistaminic medications, was accomplished…”
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Selective fluorescence labeling of myristicin using Mizoroki-Heck coupling reaction. Application to nutmeg powder, oil, and human plasma samples
Published in Journal of Chromatography A (11-10-2022)“…•First fluorescence labeling for the major toxic nutmeg constituent myristicin.•New labeling was based on Mizoroki-Heck coupling for myristicin terminal…”
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Micellar Liquid Chromatography from Green Analysis Perspective
Published in Open Chemistry (01-01-2015)“…Micellar liquid chromatography (MLC) is a simple well-established branch of high-performance liquid chromatography. The applications of MLC for the…”
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Analytical method for lipoperoxidation relevant reactive aldehydes in human sera by high-performance liquid chromatography–fluorescence detection
Published in Analytical biochemistry (01-11-2014)“…A validated, simple and sensitive HPLC method was developed for the simultaneous determination of lipoperoxidation relevant reactive aldehydes: glyoxal (GO),…”
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Two Versatile Pencil Graphite-Polymer Sensor Electrodes Coupled with Potentiometry and Potentiometric Titration Methods: Profiling Determinations of Vitamin V in Tablets and Urine Samples
Published in Sensors (Basel, Switzerland) (24-11-2022)“…Herein, we developed a new pencil graphite ion-selective electrode strategy for the broadly used erectile dysfunction medication, sildenafil citrate (SC,…”
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Determination Method for Pyrroloquinoline Quinone in Food Products by HPLC-UV Detection Using a Redox-Based Colorimetric Reaction
Published in Chemical & pharmaceutical bulletin (01-01-2022)“…We have developed an HPLC-UV method for the determination of pyrroloquinoline quinone (PQQ), which utilizes a redox-based colorimetric reaction. In the…”
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Harnessing Oleanolic Acid and Its Derivatives as Modulators of Metabolic Nuclear Receptors
Published in Biomolecules (Basel, Switzerland) (28-09-2023)“…Nuclear receptors (NRs) constitute a superfamily of ligand-activated transcription factors with a paramount role in ubiquitous physiological functions such as…”
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Design, Synthesis, Biological Evaluation, and Molecular Dynamics Studies of Novel Lapatinib Derivatives
Published in Pharmaceuticals (Basel, Switzerland) (28-12-2022)“…Co-expression of the epidermal growth factor receptor (EGFR, also known as ErbB1) and human epidermal growth factor receptor 2 (HER2) has been identified as a…”
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Chromatographic methods and sample pretreatment techniques for aldehydes determination in biological, food, and environmental samples
Published in Journal of pharmaceutical and biomedical analysis (25-10-2019)“…•Aldehydes are present in various matrices including biological, food, and environments.•Aldehydes can be used as diseases biomarkers and food quality…”
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Unique biomedical application of fluorescence derivatization based on palladium‐catalyzed coupling reactions for HPLC analysis of pharmaceuticals and biomolecules
Published in Biomedical chromatography (01-07-2024)“…Palladium‐catalyzed coupling reactions are versatile and powerful tools for the construction of carbon–carbon bonds in organic synthesis. Although these…”
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Synchronous fluorescence spectrofluorimetric method for the simultaneous determination of metoprolol and felodipine in combined pharmaceutical preparation
Published in BMC chemistry (07-11-2011)“…A rapid, simple and sensitive synchronous specrtofluorimetric method has been developed for the simultaneous analysis of binary mixture of metoprolol (MTP) and…”
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Scaffold Repurposing Reveals New Nanomolar Phosphodiesterase Type 5 (PDE5) Inhibitors Based on Pyridopyrazinone Scaffold: Investigation of In Vitro and In Silico Properties
Published in Pharmaceutics (01-09-2022)“…Inhibition of PDE5 results in elevation of cGMP leading to vascular relaxation and reduction in the systemic blood pressure. Therefore, PDE5 inhibitors are…”
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Detection of hydrogen sulfide in water samples with 2-(4-hydroxyphenyl)-4,5-di(2-pyridyl)imidazole-copper(II) complex using environmentally green microplate fluorescence assay method
Published in Analytica chimica acta (30-05-2019)“…Hydrogen sulfide (H2S) is a colorless toxic gas which can be found as HS− in rivers and waste waters especially in the occupational susceptible environment…”
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A sensitive chemiluminescence detection approach for determination of 2,4-dinitrophenylhydrazine derivatized aldehydes using online UV irradiation – luminol CL reaction. Application to the HPLC analysis of aldehydes in oil samples
Published in Talanta (Oxford) (01-10-2021)“…Aldehydes are toxic carbonyl compounds that are identified in various matrices surrounding us. For instance, aldehydes could be formed during the cooking and…”
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Development of a Selective Assay of Tyrosine and Its Producing and Metabolizing Enzymes Utilizing Pulse-UV Irradiation-Induced Chemiluminescence
Published in Analytical chemistry (Washington) (23-08-2022)“…A new pulse UV irradiation-induced chemiluminescence (CL) determination method was developed for l-tyrosine using the luminol derivative L-012. The proposed…”
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Aromatic aldehydes as selective fluorogenic derivatizing agents for α‐dicarbonyl compounds. Application to HPLC analysis of some advanced glycation end products and oxidative stress biomarkers in human serum
Published in Journal of pharmaceutical and biomedical analysis (05-09-2018)“…[Display omitted] •A novel approach for fluorogenic derivatization of α-dicarbonyls was developed.•Ammonium acetate and aromatic aldehydes are used as one-pot…”
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Inclusive study of peanut shells derived activated carbon as an adsorbent for removal of lead and methylene blue from water
Published in Scientific reports (12-06-2024)“…Green and efficient agro-waste-based activated carbon has been prepared utilizing peanut shells for adsorptive elimination of an industrial dye, methylene…”
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A Comparative Study on the Reduction Modes for Quinone to Determine Ubiquinone by HPLC with Luminol Chemiluminescence Detection Based on the Redox Reaction
Published in Molecules (Basel, Switzerland) (22-12-2022)“…Ubiquinone (UQ) is considered one of the important biologically active molecules in the human body. Ubiquinone determination in human plasma is important for…”
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