Search Results - "Ekwudo, Millicent"
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The microbiota-gut-brain axis in Huntington's disease: pathogenic mechanisms and therapeutic targets
Published in The FEBS journal (01-03-2024)“…Huntington's disease (HD) is a currently incurable neurogenerative disorder and is typically characterized by progressive movement disorder (including chorea),…”
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Bacteroidota inhibit microglia clearance of amyloid-beta and promote plaque deposition in Alzheimer’s disease mouse models
Published in Nature communications (08-05-2024)“…The gut microbiota and microglia play critical roles in Alzheimer’s disease (AD), and elevated Bacteroides is correlated with cerebrospinal fluid amyloid-β…”
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Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice
Published in International journal of molecular sciences (29-08-2024)“…Cosmic radiation experienced during space travel may increase the risk of cognitive impairment. While simulated galactic cosmic radiation (GCRsim) has led to…”
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4
The interplay between prior selection, mild intermittent exposure, and acute severe exposure in phenotypic and transcriptional response to hypoxia
Published in Ecology and evolution (01-10-2022)“…Hypoxia has profound and diverse effects on aerobic organisms, disrupting oxidative phosphorylation and activating several protective pathways. Predictions…”
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Lack of age-related respiratory changes in Daphnia
Published in Biogerontology (Dordrecht) (01-02-2022)“…Aging is a multifaceted process of accumulation of damage and waste in cells and tissues; age-related changes in mitochondria and in respiratory metabolism…”
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The emerging role of the microbiome in Alzheimer's disease
Published in International review of neurobiology (2022)“…Alzheimer's disease (AD) is the most prevalent form of dementia and can be influenced by genetic and environmental factors. Recent studies suggest that the…”
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High-salt diet induces microbiome dysregulation, neuroinflammation and anxiety in the chronic period after mild repetitive closed head injury in adolescent mice
Published in Brain communications (2024)“…Abstract The associations between human concussions and subsequent sequelae of chronic neuropsychiatric and cardiovascular diseases such as hypertension have…”
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Stool GFAP Is Elevated in Progressive MS, Is Associated with Disability, and Predicts Disease Worsening (S42.004)
Published in Neurology (09-04-2024)“…Abstract only…”
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Identification of environmental factors that promote intestinal inflammation
Published in Nature (London) (24-11-2022)“…Genome-wide association studies have identified risk loci linked to inflammatory bowel disease (IBD) 1 —a complex chronic inflammatory disorder of the…”
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Salt diet Induces Neuroinflammatory Response, Microbiome Dysregulation and Associated with Long-term Anxiety Following Repetitive Closed Head Injury. (S28.003)
Published in Neurology (25-04-2023)“…Abstract only…”
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Effects of Respiratory Perturbations on Aging and Healthspan in Daphnia Magna
Published 01-01-2021“…Aging is a degenerative process characterized by a decline in physiological functions and cellular activities. Environmental and pharmacological interventions…”
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Dissertation