Search Results - "Ekulu, Pepe M."
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APOL1 Risk Genotypes Are Associated With Early Kidney Damage in Children in Sub-Saharan Africa
Published in Kidney international reports (01-07-2019)“…Apolipoprotein-L1 ( ) risk variants G1 and G2 increase the risk of chronic kidney disease (CKD), including HIV-related CKD, among African Americans. However,…”
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Novel Human Podocyte Cell Model Carrying G2/G2 APOL1 High-Risk Genotype
Published in Cells (Basel, Switzerland) (28-07-2021)“…Apolipoprotein L1 (APOL1) high-risk genotypes (HRG), G1 and G2, increase the risk of various non-diabetic kidney diseases in the African population. To date,…”
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HIV-associated nephropathy in children: challenges in a resource-limited setting
Published in Pediatric nephrology (Berlin, West) (01-08-2023)“…HIV infection remains one of the leading causes of morbidity and mortality worldwide, especially in children living in resource-limited settings. Although the…”
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Relevance of repeated analyses of albuminuria and glomerular filtration rate in African children with sickle cell anaemia
Published in British journal of haematology (01-09-2024)“…Glomerular hyperfiltration and albuminuria are frequent kidney abnormalities in children with sickle cell anaemia (SCA). However, little is known about their…”
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A promising pediatric peritoneal dialysis experience in a resource-limited setting with the support of saving young lives program
Published in Peritoneal dialysis international (01-09-2020)“…In the Democratic Republic of Congo (DRC), acute kidney injury (AKI) contributes to the high rate of child mortality owing to the conjunction of poverty,…”
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A focus on the association of Apol1 with kidney disease in children
Published in Pediatric nephrology (Berlin, West) (01-04-2021)“…Individuals of African origin have an increased risk of developing various progressive chronic kidney diseases (CKD). This risk has been attributed to genetic…”
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Acute renal failure in Congolese children: a tertiary institution experience
Published in Acta Paediatrica (01-11-2012)“…Aim: Published data on acute renal failure in children from the Democratic Republic of Congo are rare. The objective of this study was to review clinical…”
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Microalbuminuria among HIV-infected antiretroviral therapy-naive children in the Democratic Republic of Congo
Published in Pediatric nephrology (Berlin, West) (01-05-2016)“…Background To determine the prevalence of microalbuminuria and associated factors among Congolese human immunodeficiency virus (HIV)-infected children. Methods…”
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Depression in children suffering from sickle cell anemia
Published in Journal of pediatric hematology/oncology (01-01-2015)“…Sickle cell anemia is a chronic illness associated with important nonmedical complications. The prevalence of depression and its clinical profile among…”
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Prevalence and determinants of microalbuminuria in children suffering from sickle cell anemia in steady state
Published in Clinical kidney journal (01-08-2017)“…BackgroundSickle cell anemia (SCA) is considered a major risk factor for renal complications. The main goal of this study was to determine the frequency of…”
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Albuminuria, serum antioxidant enzyme levels and markers of hemolysis and inflammation in steady state children with sickle cell anemia
Published in BMC nephrology (17-11-2016)“…Oxidative stress is thought to be involved in the pathogenesis of microalbuminuria in Sickle cell anemia (SCA). Antioxidant enzymes such as glutathione…”
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Nocturnal enuresis in children in Kinshasa, Democratic Republic of Congo
Published in Acta Paediatrica (01-10-2012)“…Aim: To determine the prevalence of nocturnal enuresis in children of Kinshasa in Democratic Republic of Congo. Methods: In all, 506 questionnaires were sent…”
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Prevalence of Sickle Cell Disease in a Pediatric Population Suffering From Severe Infections: A Congolese Experience
Published in Hemoglobin (01-01-2014)“…Abstract Neonatal screening for sickle cell anemia is not a common practice in the Democratic Republic of Congo (DRC). Children with sickle cell disease are…”
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A rare occurrence of hairy cell leukemia in a congolese child: a presentation and challenge of diagnosis in low resource settings
Published in Journal of pediatric hematology/oncology (01-11-2013)“…Hairy cell leukemia is a rare form of leukemia and has been rarely reported in African and pediatric population. We are reporting a 4-year-old child who was…”
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Prevalence and Determinants of Sickle Cell Nephropathy in Children Living in a Low-Resource Setting: PO2355
Published in Journal of the American Society of Nephrology (01-10-2020)Get full text
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Molecular and Functional Characterization of Human Urinary APOL1 G2/G2 High-Risk Genotype Podocyte: PO1668
Published in Journal of the American Society of Nephrology (01-10-2021)Get full text
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