Search Results - "Ekstrom, Lena"

A supraphysiological dose of testosterone induces nitric oxide production and oxidative stress by Skogastierna, Cristine, Hotzen, Maja, Rane, Anders, Ekström, Lena

“…Background Accumulating evidence indicates that abuse of anabolic androgenic steroids may cause cardiovascular adverse side-effects, including endothelial…”
Get full text

Doping Test Results Dependent on Genotype of Uridine Diphospho-Glucuronosyl Transferase 2B17, the Major Enzyme for Testosterone Glucuronidation by Schulze, Jenny Jakobsson, Lundmark, Jonas, Garle, Mats, Skilving, Ilona, Ekström, Lena, Rane, Anders

“…Context: Testosterone abuse is conventionally assessed by the urinary testosterone/epitestosterone (T/E) ratio, levels above 4.0 being considered suspicious…”
Get full text

Effect of UGT1A4, UGT2B7, UGT2B15, UGT2B17 and ABC1B polymorphisms on lamotrigine metabolism in Danish patients by Petrenaite, Vaiva, Öhman, Inger, Jantzen, Frederik Peter Thal, Ekström, Lena

“…To evaluate the impact of genetic polymorphisms of UGT enzymes (UGT1A4, UGT2B7, UGT2B15 and UGT 2B17) and the transporter protein ABCB1 on Lamotrigine (LTG)…”
Get full text

Serum androgen profile and physical performance in women Olympic athletes by Eklund, Emma, Berglund, Bo, Labrie, Fernand, Carlström, Kjell, Ekström, Lena, Hirschberg, Angelica Lindén

“…The role of endogenous androgens for body composition and physical performance in women athletes is still not elucidated. To examine the serum androgen profile…”
Get more information

Disposition of Urinary and Serum Steroid Metabolites in Response to Testosterone Administration in Healthy Women by Elings Knutsson, Jona, Andersson, Alexander, Baekken, Lasse Vestli, Pohanka, Anton, Ekström, Lena, Hirschberg, Angelica Lindén

“…Abstract Context Little is known about how exogenous testosterone (T) affects the steroid profile in women. More knowledge would give the antidoping community…”
Get full text

Androgens and doping tests: genetic variation and pit‐falls by Rane, Anders, Ekström, Lena

“…The large variation in disposition known for most drugs is also true for anabolic androgenic steroids. Genetic factors are probably the single most important…”
Get full text

Digit Ratio (2D:4D) and Physical Performance in Female Olympic Athletes by Eklund, Emma, Ekström, Lena, Thörngren, John-Olof, Ericsson, Magnus, Berglund, Bo, Hirschberg, Angelica Lindén

“…Background: The second to fourth digit ratio (2D:4D ratio) is suggested to be a negative correlate of prenatal testosterone. Little is known about the role of…”
Get full text

Lived experiences of closeness to a person using Anabolic androgenic steroids a next of kin perspective by Börjesson, Annica, Ekebergh, Margaretha, Dahl, Marja-Liisa, Ekström, Lena, Lehtihet, Mikael, Vicente, Veronica

“…Anabolic androgenic steroids (AAS) are used for their aesthetic and performance-enhancing effects and are associated with physical and psychological side…”
Get full text

Variations in biomarkers of dyslipidemia and dysbiosis during the menstrual cycle: a pilot study in healthy volunteers by Bergström, Helena, Ekström, Lena, Warnqvist, Anna, Bergman, Peter, Björkhem-Bergman, Linda

“…Dyslipidemia in metabolic syndrome may introduce an underestimation of the risk for cardiovascular disease (CVD) using Low-Density Lipoprotein-Cholesterol…”
Get full text

Optimizing detection of erythropoietin receptor agonists from dried blood spots for anti‐doping application by Heiland, Carmel E., Ericsson, Magnus, Pohanka, Anton, Ekström, Lena, Marchand, Alexandre

“…The World Anti‐Doping Agency (WADA) has recently implemented dried blood spots (DBSs) as a matrix for doping control. However, specifications regarding the…”
Get full text

UGT polymorphisms and lamotrigine clearance during pregnancy by Petrenaite, Vaiva, Öhman, Inger, Ekström, Lena, Sæbye, Ditte, Hansen, Thomas Folkmann, Tomson, Torbjörn, Sabers, Anne

“…•Genetic polymorphism of UGT1A4 T142G and UGT2B7 C802T influences LTG clearance changes during pregnancy and post-partum.•Homozygous carriers of UGT2B7 C802T…”
Get full text

Tissue distribution and relative gene expression of UDP-glucuronosyltransferases (2B7, 2B15, 2B17) in the human fetus by Ekström, Lena, Johansson, Maria, Rane, Anders

“…UDP-glucuronosyltransferases (UGTs) catalyze phase II conjugation reactions and play an important role in the inactivation and elimination of several drugs. It…”
Get full text

Detection of anabolic agents including selective androgen receptor modulators in samples outside of sport by Bohlin, Kim Petterson, Pohanka, Anton, Andersson, Alexander, Villén, Tomas, Ekström, Lena

“…Selective androgen receptor modulators (SARMs) are prohibited by the World Anti‐Doping Agency (WADA) since 2008. Similarly, to anabolic androgenic steroids…”
Get full text

Urinary steroid profile in relation to the menstrual cycle by Schulze, Jenny, Suominen, Tina, Bergström, Helena, Ericsson, Magnus, Björkhem Bergman, Linda, Ekström, Lena

“…The interpretation of the steroidal module of the Athlete Biological Passport (ABP) in female athletes is complex due to the large variation of the endogenous…”
Get full text

Expression of CYP3A4 and CYP3A7 in Human Foetal Tissues and its Correlation with Nuclear Receptors by Betts, Stina, Björkhem‐Bergman, Linda, Rane, Anders, Ekström, Lena

“…Previous reports have suggested that the nuclear receptors vitamin D receptor (VDR), peroxisome proliferator‐activated receptor α (PPARα), pregnane X receptor…”
Get full text

Supra‐physiological doses of anabolic androgenic steroids impact erythropoietin and blood parameters by Heiland, Carmel E., Schickel, Yasmin, Lehtihet, Mikael, Börjesson, Annica, Ekström, Lena

“…Hematological parameters and erythropoiesis are known to be influenced by anabolic androgenic steroid (AAS) use. However, little is known in relation to…”
Get full text

Detection of anabolic androgenic steroids in serum samples by Makvandi, Bahare, Pohanka, Anton, Bergström, Mats, Börjesson, Annica, Lehtihet, Mikael, Ekström, Lena, Zheng, Yufang

“…When testing for anabolic androgenic steroids (AAS) outside sports communities, for example, in healthcare and forensic medicine, urine is the matrix of…”
Get full text

Disposition of serum steroids in response to combined oral contraceptives and menstrual cycle phases: A double‐blind, randomized, placebo‐controlled study by Knutsson, Jona Elings, Ekström, Lena, Hirschberg, Angelica Lindén

“…To analyze doping control samples from female athletes demands understanding of non‐doping factors that affect the steroid profile. These could be…”
Get full text

Intra‐individual stability of longitudinal urinary steroid profiles in Swedish athletes by Ekström, Lena, Mous, Dinah, Heiland, Vincent, Heiland, Emerald G., Schulze, Jenny

“…The steroid module of the athlete biological passport (ABP) aims to detect doping with endogenous steroids by longitudinally monitoring epitestosterone (E),…”
Get full text

Vitamin D3 supplementation in patients with frequent respiratory tract infections: a randomised and double-blind intervention study by Bergman, Peter, Norlin, Anna-Carin, Hansen, Susanne, Rekha, Rokeya Sultana, Agerberth, Birgitta, Björkhem-Bergman, Linda, Ekström, Lena, Lindh, Jonatan D, Andersson, Jan

“…Background Low serum levels of 25-hydroxyvitamin D3 are associated with an increased risk of respiratory tract infections (RTIs). Clinical trials with vitamin…”
Get full text